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Methyl 3-amino-4-methylthiophene-2-carboxylate

CAS No.: 85006-31-1

Chemical Name:: Methyl 3-amino-4-methylthiophene-2-carboxylate

Synonyms: 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER;3-Amino Articaine;3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER;M3A4MT2C;Articaine-002;Articaine Impurity I;Articaine Impurity 9;LABOTEST-BB LT00453517;Articaine EP Impurity I;Articaine intermediate E

CBNumber:: CB0189112

Molecular Formula:: C7H9NO2S

Molecular Weight:: 171.22

MOL File:: 85006-31-1.mol

MSDS File:: SDS

Modify Date:: 2024/5/29 17:03:55

Request For Quotation

Methyl 3-amino-4-methylthiophene-2-carboxylate Properties

Melting point	85-88 °C (lit.)
Boiling point	318.6±37.0 °C(Predicted)
Density	1.264±0.06 g/cm3(Predicted)
Flash point	>100°C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	1.71±0.10(Predicted)
form	Solid
color	Pale Yellow
Water Solubility	1g/L at 35℃
BRN	973196
InChIKey	YICRPERKKBDRSP-UHFFFAOYSA-N
LogP	1.28
CAS DataBase Reference	85006-31-1(CAS DataBase Reference)
NIST Chemistry Reference	Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-24/25-22

WGK Germany

Hazard Note

Irritant

HS Code

29349990

NFPA 704

	1
2		0

Methyl 3-amino-4-methylthiophene-2-carboxylate price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	546658	Methyl 3-amino-4-methylthiophene-2-carboxylate 97%	85006-31-1	5G	₹5823.85	2022-06-14	Buy
Sigma-Aldrich(India)	546658	Methyl 3-amino-4-methylthiophene-2-carboxylate 97%	85006-31-1	25G	₹14873.55	2022-06-14	Buy
ALFA India	ALF-A10115-22	Methyl 3-amino-4-methylthiophene-2-carboxylate, 98%	85006-31-1	100g	₹35985	2022-05-26	Buy
TCI Chemicals (India)	M1772	Methyl 3-Amino-4-methylthiophene-2-carboxylate min. 98.0 %	85006-31-1	5G	₹3900	2022-05-26	Buy
TCI Chemicals (India)	M1772	Methyl 3-Amino-4-methylthiophene-2-carboxylate min. 98.0 %	85006-31-1	25G	₹10300	2022-05-26	Buy

Product number	Packaging	Price	Buy
546658	5G	₹5823.85	Buy
546658	25G	₹14873.55	Buy
ALF-A10115-22	100g	₹35985	Buy
M1772	5G	₹3900	Buy
M1772	25G	₹10300	Buy

Methyl 3-amino-4-methylthiophene-2-carboxylate Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

Methyl 3-Amino-4-methylthiophene-2-carboxylate is a versatile reactant used in various syntheses. It is used in the preparation of (oxalylamino)benzoic acids and (carboxyheteroarylamino)oxalic acids as selective and orally bioavailable nonpeptide inhibitors of protein-tyrosine phosphatase 1B.

Application

methyl 3-amino-4-methylthiophene-2-carboxylate is the starting material used in the synthesis of the local anesthetic articaine.
7-Methylthieno[3,2-d]pyrimidin-4(3H)-one was prepared using methyl 3-amino-4-methylthiophene-2-carboxylate.
The reaction of 4-bromotoluene (0.171 g, 1 mmol), methyl 3-amino-4-methylthiophene-2-carboxylate(0.342 g, 2 mmol) and KOAc (0.196 g, 2 mmol) in the presence of PdCl(C3H5)(dppb) (12.2 mg, 0.02mmol) in DMAc at 120 °C affords the corresponding Methyl 3-amino-4-methyl-5-p-tolylthiophene-2-carboxylate in 81% (0.212 g) isolated yield.

Methyl 3-amino-4-methylthiophene-2-carboxylate Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Sodium hydride Ethanol Hydroxylamine hydrochloride Methyl methacrylate

Methyl 2-Methyl-3-Oxo-Tetrahydrothiophene-2-Carbonate 4-METHYL-3-AMINO-2-(METHOXYCARBONYL)-4,5-DIHYDROTHIOPHENE

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Preparation Products

Thieno[3,2-d]pyrimidine-7-carboxylic acid, 4-chloro- METHYL 3-CHLORO-4-METHYLTHIOPHENE-2-CARBOXYLATE Methyl 3-dimethylamino-4-methylthiophene-2-carboxylate, 97% Thieno[3,2-d]pyriMidine, 2-chloro-7-Methyl-4-(4-Morpholinyl)- 7-(BROMOMETHYL)-2-CHLOROTHIENO[3,2-D]PYRIMIDINE

7-Methylthieno[3,2-d]pyrimidine-2,4-diol tert-butyl 4-methylthiophen-3-ylcarbamate 5-Chlorothieno[3,2-b]pyridine-3-carboxylic acid

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Methyl 3-amino-4-methylthiophene-2-carboxylate Suppliers

Global( 406)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SYNOVA CHEMICALS	+91-9920741772 +91-9920741772	Mumbai, India	428	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
Valeshvar Biotech	+91-9979864728 +91-9979864728	Gujarat, India	4	58	Inquiry
CHEMAZON LABORATORIES	+91 9848551964	Hyderabad, India	1320	58	Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd.	+91-26463395 +91-7926462688	Gujarat, India	1615	58	Inquiry
Denisco Chemicals Pvt Ltd	+91-9989050751	Telangana, India	249	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6913	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Denisco Chemicals Pvt., Ltd.	91-40-23552990	Hyderabad, India	174	58	Inquiry

Supplier	Advantage
SYNOVA CHEMICALS	58
JSK Chemicals	58
Valeshvar Biotech	58
CHEMAZON LABORATORIES	58
Rivashaa Agrotech Biopharma Pvt. Ltd.	58
Denisco Chemicals Pvt Ltd	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Denisco Chemicals Pvt., Ltd.	58

Methyl 3-amino-4-methylthiophene-2-carboxylate Spectrum

Methyl 3-amino-4-methylthiophene-2-carboxylate(85006-31-1)IR

85006-31-1(Methyl 3-amino-4-methylthiophene-2-carboxylate)Related Search:

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Methyl carbamate Methyl METHYL 3-AMINO-4-CYANOTHIOPHENE-2-CARBOXYLATE

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M3A4MT2C METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLATE Methyl 3-amino-4-methyl-2-thenoate METHYL 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLATE LABOTEST-BB LT00453517 3-AMINO-4-METHYLTHIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Methyl 3-Amino-4-Methylthiophen-2-Carboxylate METHYL 3-AMINO-4-METHYLTHIOPHENE-2-CARBO 3-Amino-4-Methyl-2-ThiophenecarboxylicMethylester Articaine intermediate E 3-Amino-2-methoxycarbonyl-4-methylthiophene 3-Amino-2-carbomethoxy-4-methylthiophen 3-Amino-4-methylthiophene-2-carboxylic 2-Thiophenecarboxylic acid, 3-amino-4-methyl-, methyl ester 4-Methyl-3-aminothiophene-2-carboxylic acid methyl ester Methyl 3-amino-4-methylthiophene-2-carboxylate ,99% 3-AMino-4-Methyl-2-thiophene carboxylic acid ester 3-Amino-2-(methoxycarbonyl)-4-methylthiophene, Methyl 3-amino-4-methyl-2-thenoate Articaine IMpurity I (Methyl 3-AMino-4-Methylthiophene-2-Carboxylate) Methyl 3-AMino-4-Methylthiophene-2-carboxylate , 98.0%(GC) Methyl3-amino-4-methylthiophene-2-carboxylate,98% Methyl 3-amino-4-methylthiophene-2-carboxylate(Articaine Intermediates) 3-AMINO 4-METHYL-2-THIOPHENE CARBOXYLICACID METHYL ESTER IMPORTED VIDE B/E 3189721/ 06.11.2015][CLEAR AGAINST ADVANCE L Articaine Impurity 9(Articaine EP Impurity I） Articaine EP Impurity I Methyl3-Amino-4-methylthiophene-2-carboxylate> Articaine-002 Articaine Impurity I 3- amino-4-methyl thiophene - 2-carboxylate, methyl ester Methyl 3-amino-4-methylthiophene-2-carboxylate ISO 9001：2015 REACH Articaine Impurities1819 Articaine Impurity 9 3-AMINO-4-METHYL-2-THIOPHENECARBOXYLIC ACID METHYL ESTER 3-AMINO-4-METHYLTHIOPHENECARBOXYLIC ACID METHYL ESTER 3-Amino Articaine Articaine Hydrochloride EP Impurity I 85006-31-1 C7H9SNO2 Heterocyclic Building Blocks Thiophenes Building Blocks Thiophenes & Benzothiophenes Building Blocks C7 to C9 Chemical Synthesis Heterocyclic Building Blocks Thiophenes Thiophen Esters Thiophenes & Benzothiophenes Thiophene&Benzothiophene Organic acids API intermediates 1 ADVANCED INT.