ChemicalBook > Product Catalog >API >Fluid, Electrolyte, and Acid-Base Balance >Electrolyte Balance Pharmacology >Etidronate disodium
Etidronate disodium
- CAS No.
- 7414-83-7
- Chemical Name:
- Etidronate disodium
- Synonyms
- Etidron;sm-5600;Calcimux;Didronel;didronelr;BA 49280E;ETIDRONATE;Sodium etidronate;sodiumethidronate;sodiumethydronate
- CBNumber:
- CB0207300
- Molecular Formula:
- C2H9NaO7P2
- Molecular Weight:
- 230.02
- MOL File:
- 7414-83-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/26 15:15:06
| Melting point | >300 °C |
|---|---|
| storage temp. | 15-25°C |
| solubility | H2O: 26 mg/mL |
| form | solid |
| color | white |
| Water Solubility | Soluble in water (26 mg/ml). |
| Merck | 14,3863 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 7414-83-7 |
| EPA Substance Registry System | Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt (7414-83-7) |
Etidronate disodium price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P5248 | Etidronate disodium hydrate ≥97% (NMR), solid | 7414-83-7 | 10MG | ₹13044.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P5248 | Etidronate disodium hydrate ≥97% (NMR), solid | 7414-83-7 | 100MG | ₹54666.25 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D4159 | Disodium Etidronate Hydrate | 7414-83-7 | 5G | ₹8100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D4159 | Disodium Etidronate Hydrate | 7414-83-7 | 25G | ₹14800 | 2022-05-26 | Buy |
Etidronate disodium Chemical Properties,Uses,Production
Description
Agents in the first generation (e.g., etidronate disodium and tiludronate) that were dosed continuously produced poorly mineralized bone, because there was no interval for appropriate bone mineralization to occur. Subsequent studies that used a cyclic dosing schedule (400 mg/day for 2 weeks, followed by 2.5 months of calcium supplementation only) showed improvement in bone mineralization. Etidronate has been approved for treatment of Paget's disease of the bone but not for treatment of osteoporosis. Tiludronate is approximately 10-fold more potent than etidronate and, when given orally for 6 months (200, 400, or 800 mg/day), increases BMD by 2%. No further bone loss was detected in patients 6 months after cessation of therapy.
Chemical Properties
White Crystalline Solid
Uses
Etidronate disodium is a bisphosphonate antiresorptive agent,it is used as a calcium regulator.
Definition
ChEBI: An organic sodium salt resulting from the replacement of two protons from etidronic acid (one from from each of the phosphonic acid groups) by sodium ions.
Safety Profile
Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of POx, and Na2O.
Etidronate disodium Preparation Products And Raw materials
Global( 357)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| New Alliance Dye Chem Pvt Ltd | +91-9820112338 +91-9820112338 | Maharashtra, India | 104 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Bhakti Chemicals Pvt Ltd | +91-9820076785 +91-9819969093 | Mumbai, India | 18 | 58 | Inquiry |
| Aquapharm Chemical Private Limited | +91-8308831947 +91-9372435961 | Maharashtra, India | 7 | 58 | Inquiry |
| Titan Pharma India Private Limited | -67856931 | Mumbai, India | 84 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| SPIC Pharma | +91 44 22350278 | Tamil Nadu, India | 4 | 58 | Inquiry |
| Ultratech India Limited | 07588106518 | Mumbai, India | 29 | 58 | Inquiry |
| U.P. Chemicals | 09988600471 | Punjab, India | 88 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| New Alliance Dye Chem Pvt Ltd | 58 |
| Ralington Pharma | 58 |
| Bhakti Chemicals Pvt Ltd | 58 |
| Aquapharm Chemical Private Limited | 58 |
| Titan Pharma India Private Limited | 58 |
| Maas Pharma Chemicals | 58 |
| SPIC Pharma | 58 |
| Ultratech India Limited | 58 |
| U.P. Chemicals | 58 |
| Pharma Affiliates | 58 |
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Sodium etidronate
didronelr
disodium(1-hydroxyethylidene)diphosphonate
disodium1-hydroxyethylidenephosphonate
disodiumdihydrogen(1-hydroxyethylidene)diphosphonate
disodiumethanol-1,1-diphosphonate
disodiumethydronate
1-Hydroxyethylidone-1,1-diphosphonicaciddisodiumsalt
1-Hydroxyethylidone-1,1-diphosphonicacidpentasodiumsalt
Pentasodiumetidronate
1-Hydroxyethylidone-1,1-diphosphonicacid
1-Hydroxyethylidone-1,1-diphosphonicacidtrisodiumsalt
Calcimux
Etidron
DIPHOSPHONICACID,(1-HYDROXYETHYLENE)-,DISODIUMSALT
DIPHOSPHONICACID,(1-HYDROXYETHYLIDENE)-,DISODIUMSALT
etidronate disodium，ETD
Dinatriumdihydrogen(1-hydroxyethyliden)bisphosphonat
1-Hydroxyethylidene-1,1-bis-(phosphonic acid) disodium salt
Phosphonicacid, P,P'-(1-hydroxyethylidene)bis-, sodiuM salt (1:2)
DisodiuM of 1-Hydroxy Ethylidene-1,1-Diphosphonic Acid (HEDPNa2)
Etidronate Disodium (200 mg)
(1-Hydroxyethane-1,1-diyl)diphosphonic acid disodi
Didronel
disodium hydroxy-[1-hydroxy-1-[hydroxy(oxidanidyl)phosphoryl]ethyl]phosphinate
disodium hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate
DisodiuM Etidronate Hydrate
1-Hydroxyethane-1,1-diphosphonic Acid DisodiuM Salt
BA 49280E
DisodiuM (1-Hydroxyethylidene)-1,1-bisphosphonate
P,P'-(1-Hydroxyethylidene)bisphosphonic Acid SodiuM Salt
Disodium 1-Hydroxyethane-1,1-diphosphonate
1-Hydroxyethane-1,1-diphosphonic Acid Disodium Salt
Etidronic Acid Disodium Salt
Etidronate disodiuM hydrate
DIHYDROGEN (1-HYDROXYETHYLIDENE)BISPHOSPHONATE DISODIUM
DISODIUM ETIDRONATE
hedp disodium salt
ETIDRONATE
ETIDRONATE DISODIUM
Etidronic acid disodium salt
ETRIDRONIC ACID, DISODIUM SALT
1-HYDROXYETHYLIDENE-1,1-DIPHOSPHONIC ACID DISODIUM SALT
(1-HYDROXYETHYLIDENE)BISPHONIC ACID
(1-HYDROXYETHYLIDENE)BISPHOSPHONIC ACID
(1-hydroxyethane-1,1-diyl)diphosphonicaciddisodiumsalt
(1-hydroxyethane-1,1-diyl)di-phosphonicacidisodiumsalt
(1-hydroxyethylidene)bis-phosphonicacidisodiumsalt
(1-hydroxyethylidene)diphosphonicacid,disodiumsalt
(1-hydroxyethylidene)di-phosphonicacidisodiumsalt
ethane-1-hydroxy-1,1-diphosphonicacid,disodiumsalt
Phosphonicacid,(1-hydroxyethylidene)bis-,disodiumsalt
sm-5600
sodiumethidronate
sodiumethydronate
ethydronate disodium
ETIDRONATE DISODIUM (1-HYDROXYETHYLIDONE-1,1-DIPHOSPHONIC ACID DISODIUM SALT)
ETIDRONATE DISODIUM USP(CRM STANDARD)
Dihydrogen (1-hydroxyethylidene)bisphosphonate disodium hydrate
disodium dihydrogen (1-hydroxyethylidene)bisphosphonate