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DL-Mandelic acid

DL-Mandelic acid Structure
CAS No.
611-72-3
Chemical Name:
DL-Mandelic acid
Synonyms
DL-Mandelic acid;DL-AMYGDALIC ACID;DL-MANDELSAEURE S;MANDELIC ACID, DL-;MANDELIC(D,L-) ACID;(R)(S)-MANDELICACID;TIMTEC-BB SBB007730;RARECHEM AL BO 1098;PHENYLGLYCOLIC ACID;PHENYLGLYCOLLIC ACID
CBNumber:
CB0287470
Molecular Formula:
C8H8O3
Molecular Weight:
152.15
MOL File:
611-72-3.mol
Modify Date:
2024/7/29 15:17:36

DL-Mandelic acid Properties

Melting point 119-121 °C(lit.)
Boiling point 234.6°C (rough estimate)
Density 1.2890
refractive index 1.4945 (estimate)
pka 3.85(at 25℃)
Water Solubility 172.5g/L(24 ºC)
CAS DataBase Reference 611-72-3(CAS DataBase Reference)
NIST Chemistry Reference Benzeneacetic acid, «alpha»-hydroxy-, (.+/-.)-(611-72-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS05
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P264-P270-P301+P312-P330-P501-P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
Risk Statements  21/22
Safety Statements  22-24/25
WGK Germany  3
RTECS  OO6300000
HS Code  29181980

DL-Mandelic acid Chemical Properties,Uses,Production

Chemical Properties

Mandelic acid turns brown when exposed to light. It can be esterified easily with alcohols in the presence of hydrogen chloride.

Physical properties

(R,S)-Mandelic acid (a-hydroxyphenylacetic acid, phenylglycolic acid), C6H5CH(OH)COOH, C8H8O3, Mr 152.15, mp 118 – 121℃, is a colorless crystalline powder. It is readily soluble in ethanol and diethyl ether, less soluble in chloroform, and insoluble in petroleum ether. Its water solubility is 15 g per 100 mL of water. In alkaline solution, mandelic acid dissolves to form salts.

Production Methods

(R,S)-mandelic acid is produced by hydrolysis of mandelic acid nitrile [532-28-5] (mp 10℃) with hydrochloric acid. Mandelic acid nitrile is obtained by the conversion of benzaldehyde [100-52-7] and hydrogen cyanide in the nascent state (NaCN + HCl) under refrigeration. Another method of producing mandelic acid is the hydrolysis of a,a-dichloroacetophenone with alkali.

DL-Mandelic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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MANDELIC(D,L-) ACID MANDELIC ACID, DL- DL-MANDELICACID(MANDELICAEIC) DL-AMYGDALIC ACID DL-ALPHA-HYDROXYPHENYLACETIC ACID DL-O-HYDROXYPHENYLACETIC ACID DL-PHENYLGLYCOLIC ACID DL-A-HYDROXYPHENYLACETIC ACID DL-2-hydroxy-2-phenylacetic acid A-HYDROXYBENZENE ACETIC ALPHA-HYDROPHENYLACETIC ACID ALPHA-HYDROXY-ALPHA-TOLUIC ACID Benzeneacetic acid, alpha-hydroxy-, (± a-Hydroxyphenylacetic acid DL-Mandelic acid ,98% rac-(R*)-Hydroxyphenylacetic acid 2-hydroxy-2-phenyl-ethanoic acid Benzeneaceticacid,alpha-hydroxy-,(+-)- dl-mandelic acid free acid DL-Mandelic acid/(+/-)-alpha-Hydroxyphenylacetic acid DL-MANDELSAEURE S DL-Mandelic acid (AMygdalic acid) (+/-)-alpha-Hydroxyphenylacetic acid DL-Mandelic acid DL-MANDELIC ACID 99+% DL-MANDELICACID,REAGENT DL-MANDELIC ACID/CYCLANDELATE,PEMOLINE DL-mandelic acid(mandelic acid) (R)(S)-MANDELICACID TIMTEC-BB SBB007730 RARECHEM AL BO 1098 PHENYLHYDROXYACETIC ACID PHENYLGLYCOLIC ACID PHENYLGLYCOLLIC ACID amygdalic acid、 mandelic acid Big Discount Purity 99% Dl-Mandelic Acid CAS?90-64-2?with Best Quality Pregabalin EP Impurity C (Glycopyrronium Bromide EP Impurity C) 611-72-3 General Use Puriss p.a. Organic Building Blocks Analytical Reagents Building Blocks Analytical Chromatography Product Catalog Carbonyl Compounds Carboxylic Acids C8 FINE Chemical & INTERMEDIATES 611-72-3