N,N-Dimethylpiperidin-4-amine
- CAS No.
- 50533-97-6
- Chemical Name:
- N,N-Dimethylpiperidin-4-amine
- Synonyms
- DIMETHYL-PIPERIDIN-4-YL-AMINE;EOS-60858;AKOS BB-9178;CHEMBRDG-BB 4018153;4-DIMETHYLAMINO-PIPERIDINE;N,N-Dimethylpiperidin-4-amin;N,N-DIMETHYLPIPERIDIN-4-AMINE;N,N-Dimethyl-4-piperidinamine;N,N''-DIMETHYLAMINOPIPERIDINE;4-DIMETHYLAMINO-PIPERIDINE 98%
- CBNumber:
- CB0394628
- Molecular Formula:
- C7H16N2
- Molecular Weight:
- 128.22
- MOL File:
- 50533-97-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/16 10:09:33
| Boiling point | 187°C |
|---|---|
| Density | 1.09g/ml |
| Flash point | 187°C |
| refractive index | 1.4760 |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | liquid |
| pka | 10.10±0.10(Predicted) |
| color | Clear, colourless |
| BRN | 1190 |
| CAS DataBase Reference | 50533-97-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H318 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 10-34-22 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | 2734 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
N,N-Dimethylpiperidin-4-amine Chemical Properties,Uses,Production
Uses
4-(Dimethylamino)piperidine is having molecular features associated with polyamine modulation of N-methyl-D-aspartate receptors. It is utilized as a mechanism for reducing the effects of alcohol dependence.
Synthesis
1-(tert-Butoxycarbonyl)-4-piperidone (998 mg, 4.75 mmol) in methanol (15 mL) was treated with dimethylamine hydrochloride (800 mg, 9.8 mmol) and sodium cyanoborohydride (270 mg, 4.3 mmol) at rt. After 4 days, concentrated HCl (10 mL) was added and the reaction was reduced in vacuo. The resulting residue was dissolved in H2O (30 mL) and treated with 2M NaOH solution to achieve a pH of 10. The aqueous solution was extracted with methylene chloride (3×20 mL) and the combined organics were dried over Na2SO4 and removed in vacuo. The resulting product is N,N-Dimethylpiperidin-4-amine (169 mg).
storage
Incompatible with air, water, oxidizing agents and heat.
N,N-Dimethylpiperidin-4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
| GOALSY PHARMA | +91-8247562464 +91-9885583385 | Hyderabad, India | 479 | 58 | Inquiry |
| Allchem Lifescience Pvt. Ltd | +919867655500 | Gujarat, India | 971 | 58 | Inquiry |
| Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | China | 138 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9332 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29892 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| BTC pharm India | 58 |
| GOALSY PHARMA | 58 |
| Allchem Lifescience Pvt. Ltd | 58 |
| Sri Neelima Laboratories | 58 |
| A.J Chemicals | 58 |
| Shanghai Boc Chemical Co., Ltd. | 58 |
| Capot Chemical Co.,Ltd. | 60 |
| Hangzhou FandaChem Co.,Ltd. | 55 |
| ATK CHEMICAL COMPANY LIMITED | 60 |
| career henan chemical co | 58 |