n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
- CAS No.
- 7084-11-9
- Chemical Name:
- n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride
- Synonyms
- EDCI;EDCL;EDAC;EDCI HCL;1-ETHYL-3-(3-DIMETHYLAMINOPROPYL)CARBODIIMIDE HYDROCHLORIDE;EDC HYDROCHLORIDE;EPCI;3-(3-DIMETHYLAMINOPROPYL)-1-ETHYLCARBODIIMIDE HYDROCHLORIDE;WSC HCL;1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE HCL
- CBNumber:
- CB0443054
- Molecular Formula:
- C8H18ClN3
- Molecular Weight:
- 191.7
- MOL File:
- 7084-11-9.mol
- Modify Date:
- 2023/11/23 17:25:00
Melting point | 110-115 °C(lit.) |
---|---|
storage temp. | Inert atmosphere,Room Temperature |
CAS DataBase Reference | 7084-11-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xi |
Risk Statements | 37/38-41 |
Safety Statements | 26-36/37/39 |
WGK Germany | 3 |
RTECS | FF2200000 |
F | 3-10-21 |
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Chemical Properties,Uses,Production
Description
Among the carbodiimides available, n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide (EDC) hydrochlorideis commonly used because it is available as an HCl salt, is easy to handle, and the urea by-product, N-(3-dimethylaminopropyl)-N' -ethylurea (EDU), is soluble in water and can easily be removed[1].
Uses
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide (EDC) is a carbodiimide coupling reagent commonly used for the preparation of amides from carboxylic acids and amines[1].
Toxicology
N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) was considered to be potentially genotoxic; however, later studies determined that EDC is not genotoxic. 4 in vitro Ames bacterial mutagenicity tests indicated EDC is genotoxic, but the reagent is not genotoxic in vivo when administered to rats orally. When administered orally, EDC is hydrolyzed to EDU, which is not genotoxic[1].
References
[1] Kai Cao, Samuel J. Bonacorsi Jr, John A. Brailsford. “Synthesis of stable-isotope-labeled N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide and N-(3-dimethylaminopropyl)-N′-ethylurea.” Journal of labelled compounds & radiopharmaceuticals 63 13 (2020): 526–530.
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Honour Lab Limited | +919845977466 | Telangana, India | 164 | 58 | Inquiry |
S S Arofine | +91-9975111566 +91-7020384585 | Maharashtra, India | 30 | 58 | Inquiry |
Noble Molecular Research | +91 9717706044 | Uttar Pradesh, India | 85 | 58 | Inquiry |
Alphahex Lifescience Pvt., Ltd. ALPL | +91-9022098162 +91-9022098162 | Maharashtra, India | 1 | 58 | Inquiry |
Greenwave Pharmaceuticals | +91-7416336643 +91-7416336643 | Telangana, India | 11 | 58 | Inquiry |
Tosco Pharmachem Pvt Ltd | +91-9573336677 +91-9573336677 | Telangana, India | 49 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Globe Chemie | 08048372441Ext 581 | Pune, India | 101 | 58 | Inquiry |
Supplier | Advantage |
---|---|
Honour Lab Limited | 58 |
S S Arofine | 58 |
Noble Molecular Research | 58 |
Alphahex Lifescience Pvt., Ltd. ALPL | 58 |
Greenwave Pharmaceuticals | 58 |
Tosco Pharmachem Pvt Ltd | 58 |
Ralington Pharma | 58 |
OCEAN TRADING CORPORATION | 58 |
A.J Chemicals | 58 |
Globe Chemie | 58 |
7084-11-9(n-(3-dimethylaminopropyl)-n'-ethylcarbodiimide hydrochloride)Related Search:
1of4
chevron_right