Entecavir
- CAS No.
- 142217-69-4
- Chemical Name:
- Entecavir
- Synonyms
- Etv;Baraclude;entikawei;2-amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one;CS-863;CS-1236;Entecavi;SQ 34676;Enticavir;ENTECAVIR
- CBNumber:
- CB0506719
- Molecular Formula:
- C12H15N5O3
- Molecular Weight:
- 277.28
- MOL File:
- 142217-69-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/5 9:46:16
| Melting point | 249-252°C |
|---|---|
| Boiling point | 661.4±65.0 °C(Predicted) |
| Density | 1.81±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly), Methanol (Sparingly) |
| pka | 14.22±0.60(Predicted) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D +25 to +40°, c = 0.2 in H2O |
| Stability | Hygroscopic |
| CAS DataBase Reference | 142217-69-4(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H320-H335 |
| Precautionary statements | P264-P270-P301+P312-P330 |
| Safety Statements | 24/25 |
| WGK Germany | 3 |
| HS Code | 29339900 |
Entecavir price More Price(2)
Entecavir Chemical Properties,Uses,Production
Chemical Properties
White to Off-White/Yellow Crystalline Powder
Definition
ChEBI: Guanine substituted at the 9 position by a 4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl group. A synthetic analogue of 2'-deoxyguanosine, it is a nucleoside reverse transcriptase inhibitor with selective antiviral activity against hepatitis B virus Entecavir is phosphorylated intracellularly to the active triphosphate form, which competes with deoxyguanosine triphosphate, the natural substrate of hepatitis B virus reverse transcriptase, inhibiting every stage of the enzyme's activity, although it ha no activity against HIV. It is used for the treatment of chronic hepatitis B.
Trade name
Baraclude (BMS)
Entecavir Preparation Products And Raw materials
Global( 509)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SEUTIC | +91-8309787199 +91-8309787199 | Hyderabad, India | 124 | 58 | Inquiry |
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| Sun Pharmaceutical Industries Ltd | +91-2242244224 +91-2243244324 | Maharashtra, India | 108 | 58 | Inquiry |
| HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
| Laurus Labs Ltd | +91-4066594333 +91-4039804333 | Telangana, India | 50 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Sumar Biotech LLP | +91-7984183709 +91-9824575381 | Gujarat, India | 22 | 58 | Inquiry |
| Aspen Biopharma Labs Pvt Ltd | +91-9248058660 +91-9248058662 | Telangana, India | 234 | 58 | Inquiry |
| Raks Pharma Pvt Ltd | +91-8924671555 +91-8924671555 | AndhraPradesh, India | 31 | 58 | Inquiry |
| Triveni Interchem Private Limited | +91-02606618618 +91-7574814001 | Gujarat, India | 42 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| SEUTIC | 58 |
| Varanous Labs Pvt Ltd | 58 |
| Sun Pharmaceutical Industries Ltd | 58 |
| HRV Global Life Sciences | 58 |
| Laurus Labs Ltd | 58 |
| Ralington Pharma | 58 |
| Sumar Biotech LLP | 58 |
| Aspen Biopharma Labs Pvt Ltd | 58 |
| Raks Pharma Pvt Ltd | 58 |
| Triveni Interchem Private Limited | 58 |
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2-Amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-3H-purin-6(9H)-one ,99.7%
(1S,3R,4S)-9-[4-Hydroxy-3-(hydroxyMethyl)-2-Methylenecyclopentyl]guanine
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Entecavir (as hydrate)
Entecavir,99%e.e.
Entecavi
ENTECAVIR, 98-102%
entecavir Baraclude
2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one, Baraclude
ENTECAVIR
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
2-Amino-9-[4-hydroxy-3-(hydroxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one
SQ 34676
6-H-Purin-6-one-,2-amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]
Entecavir USP Impurity B
2-amino-9-[(1R,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-3H-purin-6-one hydrate
CS-863
CS-1236
Entecavir, BMS200475
Entecavir（SQ 34676
Entecavir/Entecavir Monohydrate
Entecavir USP/EP/BP
2-Amino-9-(4-hydroxy-3-hydroxymethyl-2-methylene-cyclopentyl)-3,9-dihydro-purin-6-one
Etv
2-amino-9-((1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
Baraclude
entikawei
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylidenecyclopentyl]-1,9-dihydro-6H-purin-6-one
2-amino-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylene-cyclopentyl]-1H-purin-6-one
142217-69-4
209216-23-6
12477-69-4
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142217-69-4