Doripenem hydrate
- CAS No.
- 364622-82-2
- Chemical Name:
- Doripenem hydrate
- Synonyms
- Finibax;2H5]-Doripenem;DoripeneM Crude;doripenem hydrate;S 4661 monohydrate;Doripenem Hydrate (S 4661);Doripenem hydrate USP/EP/BP;Doripenem monohydrate, >=99%;DORIPENEM MONOHYDRATE STERILE;Doripenem Hydrate/Doribax/S-4661/Finibax
- CBNumber:
- CB0511313
- Molecular Formula:
- C15H26N4O7S2
- Molecular Weight:
- 438.51
- MOL File:
- 364622-82-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 17:06:34
| Melting point | 173°C(dec.)(lit.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: soluble5mg/mL, clear (warmed) |
| form | powder |
| color | white to beige |
| PH | Dissolve 0.3g of Doripenem Hydrate in 30mL of water: the pH of the solution is between 4.5 and 6.0. |
| BRN | 15340136 |
| InChIKey | NTUBEBXBDGKBTJ-WGLOMNHJSA-N |
| CAS DataBase Reference | 364622-82-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H341 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
| WGK Germany | 3 |
| HS Code | 2935.90.9500 |
Doripenem hydrate price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1220 | Doripenem hydrate ≥98% (HPLC) | 364622-82-2 | 10MG | ₹10825 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1220 | Doripenem hydrate ≥98% (HPLC) | 364622-82-2 | 50MG | ₹43613.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 32138 | Doripenem monohydrate VETRANAL?, analytical standard | 364622-82-2 | 25MG | ₹15241.6 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D5249 | Doripenem Monohydrate | 364622-82-2 | 50MG | ₹11800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5249 | Doripenem Monohydrate | 364622-82-2 | 250MG | ₹28800 | 2022-05-26 | Buy |
Doripenem hydrate Chemical Properties,Uses,Production
Description
Doripenem hydrate is a carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.
Doripenem hydrate was first approved by Pharmaceuticals and Medical Devices Agency of Japan (PMDA) on July 25, 2005, then approved by the U.S. Food and Drug Administration (FDA) on Oct 12, 2007, and approved by European Medicines Agency (EMA) on July 25, 2008. It was developed by Shionogi and Janssen, then marketed as Finibax® in Japan and as Doribax® in the US by Shionogi and as Doribax® by Janssen in BE.
Chemical Properties
Doripenem Hydrate occurs as a white to pale yellow-brown-white crystalline powder. It is sparingly soluble in water, slightly soluble in methanol, and practically insoluble in ethanol (99.5). It is gradually colored to pale yellow-brown-white by light.
Uses
Doripenem (doripenem monohydrate) is an ultra-broad spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It is particularly active against Pseudomonas aeruginosa
Biochem/physiol Actions
Doripenem is an ultra-broad spectrum carbopenem antibiotic. Doripenem is active against both gram-positive and gram-negative bacteria.
Doripenem hydrate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BDR Pharmaceuticals International Pvt Ltd | +91-2240560560 +91-7718884418 | Maharashtra, India | 206 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Manus Aktteva | +91 (79) 6512-3395 | New Delhi, India | 581 | 34 | Inquiry |
| UNIMARK REMEDIES LTD | +91-022-67304000 | New Delhi, India | 37 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
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