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Meropenem

Meropenem Structure
CAS No.
96036-03-2
Chemical Name:
Meropenem
Synonyms
MEROPENAM;MeropeneM Crude;Meropenem hydrate;(4r,5s,6s)-3-[[(3s,5s)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;STERILE MEROPENEM;Merrem;4R,5S,6S)-3-[[(3S,5S)-5-[(Dimeth-ylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;SM 7338;Meronem;Meropen
CBNumber:
CB7459533
Molecular Formula:
C17H25N3O5S
Molecular Weight:
383.46
MOL File:
96036-03-2.mol
MSDS File:
SDS
Modify Date:
2024/8/21 22:41:43
Request For Quotation

Meropenem Properties

Boiling point 627.4±55.0 °C(Predicted)
Density 1.42±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility insoluble in EtOH; ≥19.15 mg/mL in DMSO; ≥9.88 mg/mL in H2O with ultrasonic
form solid
pka 4.27±0.60(Predicted)
color White to off-white
InChI InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1
InChIKey DMJNNHOOLUXYBV-PQTSNVLCSA-N
SMILES N12[C@@]([H])([C@@H]([C@H](O)C)C1=O)[C@@H](C)C(S[C@H]1C[C@@H](C(N(C)C)=O)NC1)=C2C(O)=O
CAS DataBase Reference 96036-03-2(CAS DataBase Reference)
EPA Substance Registry System Meropenem (96036-03-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
HS Code  29419000

Meropenem Chemical Properties,Uses,Production

Description

Meropenem is a new carbapenem antibiotic introduced to market for the i.v. treatment of a wide variety of hospital infections such as lower respiratory tract, urinary tract, intraabdominal, gynecological and polymicrobial infections. Meropenem has a broad spectrum of antibacterial activity against most clinically important Gram-positive and Gramnegative aerobic and anaerobic bacteria with especially high potency against multiresistant Enterobacteriaceae and Pseudornonas aeruginosa. Compared with imipenem, the only other available carbapenem antibiotic, meropenem has the advantage of being dehydropeptidase 1 (DHP-1) stable and therefore does not need to be administered in conjunction with the DHP-1 inhibitor cilastatin. Meropenem is also being evaluated for treatment of resistant pseudomonal infections in cystic fibrosis patients.

Chemical Properties

1KG;

Uses

Meropenem, is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia.

Clinical Use

Meropenem is a synthetic carbapenem possessing a complex side chain at C-3. It also has a chiral methyl group at C-4. This methyl group conveys intrinsic resistance to hydrolysis by dehydropeptidase-1. As a consequence, it can be administered as a single agent for the treatment of severe bacterial infections.

Meropenem Preparation Products And Raw materials

Raw materials

DIETHYLALUMINUM CHLORIDE Hydrogen Methanesulfonyl chloride Ethyl chloroformate Triethylamine
N,N-Diisopropylethylamine Thioacetic acid tert-Butyldimethylsilyl chloride Palladium hydroxide ZINC
benzyl 2-bromopropanoate
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Preparation Products

Meropenem Suppliers

Global( 438)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Honour Lab Limited +919845977466 Telangana, India 164 58 Inquiry
HRV Global Life Sciences +91-9820219686 +91-9820219686 Telangana, India 379 58 Inquiry
PROTECH TELELINKS +91-8571891912 +91-9855060837 Himachal Pradesh, India 62 58 Inquiry
Aspen Biopharma Labs Pvt Ltd +91-9248058660 +91-9248058662 Telangana, India 234 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Triveni Interchem Private Limited (Group Of Triveni... 08046042087 Gujarat, India 497 58 Inquiry
Kotalwar Agencies 08046037040 Maharashtra, India 2 58 Inquiry
United Speciality Pharma 08046072091 Mumbai, India 5 58 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
Supplier Advantage
Honour Lab Limited 58
HRV Global Life Sciences 58
PROTECH TELELINKS 58
Aspen Biopharma Labs Pvt Ltd 58
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
Triveni Interchem Private Limited (Group Of Triveni... 58
Kotalwar Agencies 58
United Speciality Pharma 58
OCEAN TRADING CORPORATION 58

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Meropenem Spectrum

Meropenem(96036-03-2)1HNMR

96036-03-2(Meropenem)Related Search:

N-Vinyl-2-pyrrolidone N-Methyl-2-pyrrolidone Pyrrolidine Thioacetic acid Polyvinylpyrrolidone
Thioacetamide Sodium thiosulfate pentahydrate Meropenem Trihydrate MAP/MVP-INTERMEDIATE OF MEROPENEM Zinc Dialkyl Dithio Phosphate(ZDDP)
Side chain for meropenem 3-(2-Bromo-1-oxopropyl)-spiro[2H-1,3-benzoxazine-2,1'-cyclohexan]-4(3H)-one 5) PROTECTED MEROPENEM,PROTECTED MEROPENEM intermediates of Meropenem 4BMA,Intermediate of Meropenem intermediates of Meropenem
Meropenem BenzylFormimidate-Hydrochloride,IntermediateOfImipenem,Meropenem,(CarbopenemDrug) desmethyl meropenem
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(4r,5s,6s)-3-[[(3s,5s)-5-dimethylcarbamoylpyrrolidin-3- )-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-,(4r-(3(s*,5s*),4-al 5-beta,6-beta(r*)))-ph antibioticsm7338 ici194660 MEROPENEM, USP STANDARD MEROPENEM, USP Meropenemanhydrous MEROPENEM(PATENTED) MEROPENEM FOR INJECTION STERILE MIXTURE OF MEROPENEM AND SODIUM CARBONATE 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)- (9CI) 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-, [4R-[3(3S*,5S*),4a,5b,6b(R*)]]- SM 7338 Meropenem MERONEM MEROPEN MEROPENEM MERREM Meronem Meropen (4R,5S,6S)-3-[[(3S,5S)-5-[(Dimethylamino)carbonyl]pyrrolidin-3-yl]thio]-6-[(R)-1-hydroxyethyl]-4α-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4R,5β)-3-[[(3S)-5β-[[(Dimethylamino)carbonyl]]pyrrolidin-3-yl]thio]-6β-[(R)-1-hydroxyethyl]-4α-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid MeropeneM API (4R,5S,6S)-3-[[(3S,5Ss)-5-(diMethylcarbaMoyl)pyrrolidin-3-yl]thio]-6-[(1r)-1-hydroxyethyl]-4-Methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid crude grade meropenem Meropenem, >=98.5% MERREM; MERONEM 1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (4R,5S,6S)- Meropenem USP/EP/BP Meropenem 10.26 Meropenem Crude/ Meropenem Mixture sterile/Pure sterile Meropenem CAS 96036-03-2 Meropenem (SM 7338) Meropenem (Secondary Standard)Q: What is Meropenem (Secondary Standard) Q: What is the CAS Number of Meropenem (Secondary Standard) (4r,5s,6s)-3-[[(3s,5s)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid MEROPENAM STERILE MEROPENEM Merrem 4R,5S,6S)-3-[[(3S,5S)-5-[(Dimeth-ylamino)carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid MeropeneM Crude Meropenem hydrate Meropenem Powder USP Standard 96036-03-2 C17H25N3O5S Active Pharmaceutical Ingredients ARAVA pharmaceutical intermediates Antibacterial Cnbio APIs 96036-03-2