Arteether
- CAS No.
- 75887-54-6
- Chemical Name:
- Arteether
- Synonyms
- SM-22;SM-227;Areether;Arteethe;Arteether;Artemotil;ARPRINOCID;NSC 665971;aArteether;Beta-Arteether
- CBNumber:
- CB11012009
- Molecular Formula:
- C17H28O5
- Molecular Weight:
- 312.4
- MOL File:
- 75887-54-6.mol
- Modify Date:
- 2023/5/18 11:31:12
| Melting point | 80-820C |
|---|---|
| alpha | D21 +154.5° (c = 1.0 in CHCl3) |
| Boiling point | 372.4±42.0 °C(Predicted) |
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| form | Solid |
| color | White |
| CAS DataBase Reference | 75887-54-6 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311+H331-H226 |
| Precautionary statements | P501-P261-P270-P240-P210-P233-P243-P241-P242-P271-P264-P280-P370+P378-P361+P364-P303+P361+P353-P301+P310+P330-P304+P340+P311-P403+P233-P403+P235-P405 |
Arteether Chemical Properties,Uses,Production
Description
Arteether reached the market in the Netherlands as a solution in sesame oil, administered by i.m. injection, for the treatment of severe malaria infections in children and adolescents. Artheether, a sesquiterpene acetal with an endoperoxide bridge, is an ether derivative of the naturally occuring compound artemisinin, the active component of Chinese herbal remedies. As the other structural analogs of artemisinin, such as artesunate or artemether, it acts rapidly against Plasmodium, the parasite responsible for the disease, during the early blood stage of its development. It also exhibits a gametocytocidal activity against Plasmodium falciparum, reducing its potential for transmission. Because the only controlled clinical studies had been performed in children and adolescents, this new antimalarial drug was only approved for young patients. Further studies in adults treated with 150 mg i.m. artemotil, once daily for three consecutive days, indicated that the drug was efficient, rapidly acting (parasite clearance time meanly 38 h) and well tolerated. A new promising achievement in the regression of malaria is the combination of artemisinin derivatives with other long-lived antimalarials as mefloquine or pyrimethamine/sulfa.
Chemical Properties
White Crystalline Solid
Uses
Derivative of Artemisinin. Antimalarial
Arteether Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Jigs Chemical ltd | +919099003427 | Gujarat, India | 239 | 58 | Inquiry |
| Micro Orgo Chem | +91-91-022-24969510 +91-9082984052 | Mumbai, India | 66 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Ipca Laboratories Ltd | +91-2262105000 +91-2262105000 | Maharashtra, India | 61 | 58 | Inquiry |
| Micron Pharmaceuticals | 91-22-24969511 | Maharashtra, India | 43 | 58 | Inquiry |
| AKASH PHARMA EXPORTS | +91-9388123451 +91-9846039283 | Kerela, India | 470 | 58 | Inquiry |
| Calyx Chemicals & Pharmaceuticals Pvt. Ltd | +91-22-285-75-037 | New Delhi, India | 61 | 30 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Jigs Chemical ltd | 58 |
| Micro Orgo Chem | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| Ralington Pharma | 58 |
| Ipca Laboratories Ltd | 58 |
| Micron Pharmaceuticals | 58 |
| AKASH PHARMA EXPORTS | 58 |
| Calyx Chemicals & Pharmaceuticals Pvt. Ltd | 30 |
| Medilink Pharmachem | 50 |
| A.J Chemicals | 58 |
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