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Ilomastat

Ilomastat Structure
CAS No.
142880-36-2
Chemical Name:
Ilomastat
Synonyms
CS-1405;SANTACRUZ;IlloMastat;sc-203979A;galardin tm;Ilomastat, >=98%;GM 6001 Ilomastat;Ilomastat (GM 6001);Galardin CS 610;IloMastat (GM6001, Galardin)
CBNumber:
CB11178927
Molecular Formula:
C20H28N4O4
Molecular Weight:
388.46
MOL File:
142880-36-2.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

Ilomastat Properties

Density 1.228±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO, and 100% ethanol.
pka 9.16±0.20(Predicted)
form Off-white solid
color White
Sensitive Moisture Sensitive
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey NITYDPDXAAFEIT-DYVFJYSZSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319
Precautionary statements  P501-P261-P270-P271-P264-P280-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
Safety Statements  22-24/25
WGK Germany  3
HS Code  29339900

Ilomastat price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 364205 GM 6001 - CAS 142880-36-2 - Calbiochem GM 6001, CAS 142880-36-2, is a potent, cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases. 142880-36-2 1MG ₹10670 2022-06-14 Buy
Sigma-Aldrich(India) M5939 (R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide >95% (HPLC) 142880-36-2 5MG ₹59569.98 2022-06-14 Buy
Sigma-Aldrich(India) 364205 GM 6001 - CAS 142880-36-2 - Calbiochem GM 6001, CAS 142880-36-2, is a potent, cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases. 142880-36-2 5MG ₹37040 2022-06-14 Buy
Product number Packaging Price Buy
364205 1MG ₹10670 Buy
M5939 5MG ₹59569.98 Buy
364205 5MG ₹37040 Buy

Ilomastat Chemical Properties,Uses,Production

Uses

Ilomastat is a metalloprotease inhibitor.

General Description

A cell-permeable, potent broad-spectrum hydroxamic acid inhibitor of matrix metalloproteinases (MMPs). [Ki = 0.4 nM for skin fibroblast collagenase (MMP-1); Ki = 0.5 nM for gelatinase A (MMP-2); Ki = 27 nM for stromelysin (MMP-3); Ki = 0.1 nM for neutrophil collagenase (MMP-8); and Ki = 0.2 nM for gelatinase B (MMP-9)]. Also prevents the release of TNF-α in vivo and in vitro and abrogates endotoxin-induced lethality in mice.

Biochem/physiol Actions

GM6001 promotes cardiovascular and hepatocellular function.

Ilomastat Preparation Products And Raw materials

Raw materials

Preparation Products

Ilomastat Suppliers

Global( 132)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Alpha Biopharmaceuticals Co., Ltd +86-15542445688 China 888 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Alfa Chemistry United States 24072 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Alpha Biopharmaceuticals Co., Ltd 58
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Zhejiang J&C Biological Technology Co.,Limited 58
Nextpeptide Inc 58
Alfa Chemistry 58
InvivoChem 58

Ilomastat Spectrum

Ilomastat(142880-36-2)1HNMR

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(2R)-N4-Hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-butanediamide Ilomastat (GM6001, Galardin) Galardin CS 610 Ilomastat, >=98% (r)-n4-hydroxy-n1-[(s)-2-(1h-indol-3-yl)-1-methylcarbamoly-ethyl]-2-isobutyl-succinamide galardin tm (R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide Galardin, GM6001, Ilomastat SANTACRUZ sc-203979A IlloMastat (R)-N1-((S)-3-(1H-Indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinami IloMastat (GM6001, Galardin) (2R)-N4-Hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-butanediamide Butanediamide, N4-hydroxy-N1-[(1S)-1-(1H-indol-3-ylmethyl)-2-(methylamino)-2-oxoethyl]-2-(2-methylpropyl)-, (2R)- GM 6001 - CAS 142880-36-2 - Calbiochem GALARDIN; ILOMASTAT; GM 6001; GM-6001 GM6001 (galardin, ilomastat) CS-1405 GM 6001 Ilomastat Ilomastat (GM 6001) (R)-N1-((S)-3-(1H-Indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide Ilomastat,GM 6001,inhibit,Matrix metalloproteinases,GM-6001,MMP,Inhibitor 142880-36-2 Inhibitors