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1-Butanesulfonyl chloride

1-Butanesulfonyl chloride Structure
CAS No.
2386-60-9
Chemical Name:
1-Butanesulfonyl chloride
Synonyms
Butane-1-sulfonyl chloride;1-ButanesuL;Butylsulfonyl;Butylsulfonylchloride;BUTANESULFONYLCHLORIDE;Butylsulfonyl chloride;1-Butylsulfonyl chloride;Butanesulphonyl chloride;N-BUTYLSULFONYL CHLORIDE;1-BUTANESULFONYL CHLORIDE
CBNumber:
CB1139240
Molecular Formula:
C4H9ClO2S
Molecular Weight:
156.63
MOL File:
2386-60-9.mol
Modify Date:
2024/6/6 17:55:34

1-Butanesulfonyl chloride Properties

Melting point -29°C
Boiling point 80-81 °C/9 mmHg (lit.)
Density 1.208 g/mL at 25 °C (lit.)
vapor pressure 0.5 mm Hg ( 20 °C)
refractive index n20/D 1.454(lit.)
Flash point 175 °F
form Liquid
color Clear colorless to light yellow or light orange
Water Solubility DECOMPOSES
Sensitive Moisture Sensitive
BRN 1748742
InChIKey WEDIIKBPDQQQJU-UHFFFAOYSA-N
CAS DataBase Reference 2386-60-9(CAS DataBase Reference)
NIST Chemistry Reference 1-Butanesulfonyl chloride(2386-60-9)
EPA Substance Registry System 1-Butanesulfonyl chloride (2386-60-9)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS05,GHS08
Signal word  Danger
Hazard statements  H227-H290-H341-H314-H335-H318
Precautionary statements  P261-P280-P305+P351+P338-P310-P210e-P260h-P303+P361+P353-P501a-P201-P202-P210-P234-P260-P264-P301+P330+P331+P310-P303+P361+P353+P310+P363-P304+P340+P310-P305+P351+P338+P310-P308+P313-P370+P378-P390-P403+P235-P405-P406-P501
Hazard Codes  C
Risk Statements  34-36/37
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
RTECS  EK5950000
10-19-21
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29049090
Toxicity mouse,LD50,intraperitoneal,> 100mg/kg (100mg/kg),Nature. Vol. 174, Pg. 737, 1954.
NFPA 704
1
3 0

1-Butanesulfonyl chloride price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) B0866 1-Butanesulfonyl Chloride 2386-60-9 25G ₹5300 2022-05-26 Buy
TCI Chemicals (India) B0866 1-Butanesulfonyl Chloride 2386-60-9 500G ₹35200 2022-05-26 Buy
ottokemi B 2284a 1-Butanesulphonyl chloride 98% 2386-60-9 25gm ₹6309 2022-05-26 Buy
Product number Packaging Price Buy
B0866 25G ₹5300 Buy
B0866 500G ₹35200 Buy
B 2284a 25gm ₹6309 Buy

1-Butanesulfonyl chloride Chemical Properties,Uses,Production

Description

1-Butanesulfonyl chloride is an antimicrobial agent that inhibits the production of inflammatory substances. It has been shown to inhibit acetylcholinesterase activity and the growth of cancer cells in vitro. 1-Butanesulfonyl chloride is a cross-linking agent that can be used to produce amides, which are used as pharmaceutical preparations for treating inflammatory diseases.

Chemical Properties

clear colourless to light yellow liquid

Uses

1-Butanesulfonyl chloride has been used in the preparation of:

  • ethyl 2-(1-butanesulfonamido)pent-4-yn-l-oate
  • 1-butanesulfonamid-N,N′-1,2-ethanediylbis
  • 1-butanesulfonamide-N,N′-1,3-propanediylbis

Purification Methods

It has a pungent odour and is LACHRYMATORY. If IR shows OH bands, then dissolve in Et2O, wash with cold saturated aqueous NaHCO3 (care since CO2 will be generated) then H2O, dry it over solid Na2SO4, filter, evaporate and distil the residue twice. Characterise it by shaking a solution in Et2O or *C6H6 with aqueous NH3, collect the solid 1-butanesulfonamide with m 48o after recrystallisation from CHCl3, CCl4 or Et2O/pet ether. [Douglass & Johnson J Am Chem Soc 60 1488 1938, Lee & Dougherty J Org Chem 5 83 1940, Beilstein 4 IV 45.]

1-Butanesulfonyl chloride Preparation Products And Raw materials

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ORGANO FINE CHEMICALS +91-91-22-42128300 +91-2242128300 Mumbai, India 258 58 Inquiry
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TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
BUTANESULFONYLCHLORIDE 1-Butanesulfonyl Chloride, 98.0%(T) 1-Butanesulfonic acid chloride Butane-1-sulfonic acid chloride 1-Butanesulfonyl chloride,99% 1-(Chlorosulphonyl)butane Butanesulphonyl chloride 1-Butanesulfonyl chloride, 99% 25GR 1-BUTANESULFONYL CHLORIDE 1-BUTANESULPHONYL CHLORIDE 1-Butylsulfonyl chloride butane-1-sulfonylchloride Butylsulfonyl chloride Butylsulfonylchloride n-butanesulphonylchloride 1-ButanesulphonylChloride99% 1-Butanesulphonyl Chloride 99% 1-Butanesulphonylchloride,98% 1-BUTANESULFONYL CHLORIDE 99% N-BUTYLSULFONYL CHLORIDE butane-1-sulphonyl chloride Butylsulfonyl 1-ButanesuL 1-Butanesulfonyl Chloride > Butane-1-sulfonyl chloride Sodium L-pyroglutamate 28874-51-3 2386-60-9 C4H9ClO2S CH3CH23SO2Cl Building Blocks Sulfonyl Halides Sulfur Compounds Organic Building Blocks SULFONYL CHLORIDE Pharmaceutical Intermediates Sulfonyl Halides Sulfur Compounds Organic Building Blocks