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ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Gliquidone

Gliquidone

Gliquidone Structure
CAS No.
33342-05-1
Chemical Name:
Gliquidone
Synonyms
ardf26;ardf26se;Glurenorm;GLIQUIDONE;Gliquidone>Gliquidone D6;GLIQUIDONE 99%;Gliquidone powder;Gliquidone Tablets;Gliquidone USP/EP/BP
CBNumber:
CB1183076
Molecular Formula:
C27H33N3O6S
Molecular Weight:
527.63
MOL File:
33342-05-1.mol
Modify Date:
2025/1/27 9:38:02
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Gliquidone Properties

Melting point 179 °C
Density 1.34±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility ≥22.4 mg/mL in DMSO; insoluble in H2O; ≥2.455 mg/mL in EtOH with gentle warming and ultrasonic
form powder to crystal
pka 5.12±0.10(Predicted)
color White to Almost white
Merck 14,4443
CAS DataBase Reference 33342-05-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Safety Statements  24/25
RTECS  DB1584250
HS Code  29147000

Gliquidone price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) CDS021537 Gliquidone 33342-05-1 100MG ₹3702.15 2022-06-14 Buy
TCI Chemicals (India) G0332 Gliquidone 33342-05-1 1G ₹3900 2022-05-26 Buy
TCI Chemicals (India) G0332 Gliquidone 33342-05-1 5G ₹8200 2022-05-26 Buy
Product number Packaging Price Buy
CDS021537 100MG ₹3702.15 Buy
G0332 1G ₹3900 Buy
G0332 5G ₹8200 Buy

Gliquidone Chemical Properties,Uses,Production

Description

Gliquidone is a second generation sulfonylurea that selectively inhibits ATP-sensitive potassium channel currents (IKATP) in pancreatic β-cells (IC50s = 0.45, 119.1, and 149.7 μM for HIT-T15 cells, cardiomyocytes, and vascular smooth muscle cells, respectively). It is also a peroxisome proliferator-activated receptor γ (PPARγ) agonist (EC50 = 10 μM in a transactivation assay). Gliquidone (0.2 nmol/g) decreases plasma levels of D-glucose and stimulates insulin release in anesthetized rats. It decreases blood glucose levels, serum alkaline phosphatase (ALP), aspartate aminotransferase (AST), and alanine aminotransferase (ALT) activities, and hepatic lipid peroxidation and increases hepatic glutathione (GSH) levels in a rat model of diabetes induced by streptozotocin (STZ; ) when administered at a dose of 10 mg/kg.

Uses

Gliquidone is an anti diabetic agent used in the treatment of hypoglycemia which leads to an increased risk in diabetic cardiovascular disease. Also used in the treatment diabetic nephropathy.

Hazard

Low toxicity by ingestion. A reproductive hazard.

Gliquidone Preparation Products And Raw materials

Raw materials

Isocyanatocyclohexane 6-bromo-1,2,3,4-tetrahydro-4,4-dimethylquinoline hydrochloride Bis(4-hydroxyphenyl) Sulfone Potassium T-Butylate p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]benzenesulphonamide

Preparation Products

Gliquidone Suppliers

Global( 282)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6768 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6754 58 Inquiry
Sign Pharma Trade Services Pvt., Ltd.(SPTS) 91-22-23481235 Mumbai, India 160 58 Inquiry
Shivam Pharma Chemicals 91-22-26403900 Maharashtra, India 656 58 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3887 58 Inquiry
Hebei Chuanghai Biotechnology Co,.LTD +86-13131129325 China 5868 58 Inquiry
Capot Chemical Co.,Ltd. +86-（0）57185586718 +86-13336195806 China 29730 60 Inquiry
Supplier Advantage
A.J Chemicals 58
CLEARSYNTH LABS LTD. 58
TCI Chemicals (India) Pvt. Ltd. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
Sign Pharma Trade Services Pvt., Ltd.(SPTS) 58
Shivam Pharma Chemicals 58
Clearsynth Labs 58
Hebei Chuanghai Biotechnology Co,.LTD 58
Capot Chemical Co.,Ltd. 60

Gliquidone Spectrum

Gliquidone(33342-05-1)1HNMR

33342-05-1(Gliquidone)Related Search:

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ETHANE Methoxydiethylborane Dimethyl sulfate (Trifluoromethoxy)benzene Dimethyl fumarate
m-Anisyl alcohol Dimethyl phthalate Dimethyl ether
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,4-dimethyl-1,3-dioxo-2(1h)-isoquinolinyl)ethyl)- ardf26 ardf26se benzenesulfonamide,n-((cyclohexylamino)carbonyl)-4-(2-(3,4-dihydro-7-methoxy-4 GLIQUIDONE 99% GLIQUIDONE Gliquidone Tablets Glurenorm N-[(Cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2(1H)-yl)ethyl]benzenesulfonamide 3-Cyclohexyl-1-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-isoquinolin-2-yl)ethyl]phenyl]sulfonyl-urea Benzenesulfonamide, N-[(cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]- Gliquidone, 98%, an anti-diabetic compound Gliquidone 33342-05-1 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea Gliquidone, 98%, anti-diabetic compound 1-cyclohexyl-3-[4-[2-(7-methoxy-4,4-dimethyl-1,3-dioxo-2-isoquinolinyl)ethyl]phenyl]sulfonylurea Gliquidone> Gliquidone Gliquidone Gliquidone Suphonamide Gliquidone USP/EP/BP Gliquidone powder Gliquidone (AR-DF26) Gliquidone D6 GliquidoneQ: What is Gliquidone Q: What is the CAS Number of Gliquidone Q: What is the storage condition of Gliquidone Gliquidone reference 3-dioxoisoquinolin-2-yl)ethyl]phenyl]sulfonylurea N-[(cyclohexylamino)carbonyl]-4-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolinyl)ethyl]-benzenesulfonamide N-(Cyclohexylcarbamoyl)-4-(2-(7-methoxy-4,4-dimethyl-1,3-dioxo-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)benzenesulfonamide C14026000 Gliquidone Gliquidone, 10 mM in DMSO 33342-05-1 3342-05-1 C27H33N3O6S Glurenorm API Active Pharmaceutical Ingredients