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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Neuronal Signaling >Histamine Receptor Inhibitors >Rupatadine

Rupatadine

Rupatadine Structure
CAS No.
158876-82-5
Chemical Name:
Rupatadine
Synonyms
Rupax;Rupafi;Rupafin;Pafinur;Rinialer;UR-12592;RUPATADINE;ROPATADINE;Rupatidine;Alergoliber
CBNumber:
CB1346639
Molecular Formula:
C26H26ClN3
Molecular Weight:
415.96
MOL File:
158876-82-5.mol
Modify Date:
2023/8/14 13:33:12
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Rupatadine Properties

Melting point 58-61°C
Boiling point 586.4±50.0 °C(Predicted)
Density 1.233±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Dichloromethane; Ethyl Acetate
form Oil
pka 6.95±0.20(Predicted)
CAS DataBase Reference 158876-82-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H413
Precautionary statements  P301+P312+P330

Rupatadine Chemical Properties,Uses,Production

Chemical Properties

Rupatadine is off white to pinkish crystalline powder. It is soluble in methanol and ethanol slightly soluble in Chloroform and insoluble inwater.

Uses

Rupatadine Fumarate is a dual antagonist of histamine H1 and platelet-activating factor receptors. Rupatadine fumarate has been approved for the treatment of allergic rhinitis and chronic urticaria in adults and children over 12 years.

Mode of action

Rupatadine is a second generation, non-sedating, long-acting histamine antagonist with selective peripheral H1receptor antagonist activity. It further blocks the receptors of the platelet-activating factor (PAF) according to in vitro and in vivo studies.
Rupatadine possesses anti-allergic properties such as the inhibition of the degranulation of mast cells induced by immunological and non-immunological stimuli, and inhibition of the release of cytokines, particularly of the tumor necrosis factors (TNF) in human mast cells and monocytes.

Rupatadine Preparation Products And Raw materials

Raw materials

Preparation Products

Rupatadine Suppliers

Global( 164)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TAGOOR LABORATORIES PVT LTD +919700187008 AndhraPradesh, India 93 58 Inquiry
PANCHSHEEL ORGANICS LTD +91-9821053955 +91-9324201019 Mumbai, India 82 58 Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd. +91-26463395 +91-7926462688 Gujarat, India 1615 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Vasudha Pharma Chem Limited 08048372444Ext 196 Andhra Pradesh, India 32 58 Inquiry
Tagoor Chemicals 09989311222 Hyderabad, India 4 58 Inquiry
Clinse Labs Private Limited. +091-40-23778611 New Delhi, India 372 30 Inquiry
TYCHE INDUSTRIES LIMITED 91-40-2354-1688 New Delhi, India 4 58 Inquiry
CADILA PHARMACEUTICALS LIMITED +91 2718 225001 New Delhi, India 13 58 Inquiry
Supplier Advantage
TAGOOR LABORATORIES PVT LTD 58
PANCHSHEEL ORGANICS LTD 58
Rivashaa Agrotech Biopharma Pvt. Ltd. 58
Ralington Pharma 58
SynZeal Research Pvt Ltd 58
Vasudha Pharma Chem Limited 58
Tagoor Chemicals 58
Clinse Labs Private Limited. 30
TYCHE INDUSTRIES LIMITED 58
CADILA PHARMACEUTICALS LIMITED 58

158876-82-5(Rupatadine)Related Search:

Ketotifen fumarate 4-Methylpyridine Stavudine Thiophanate-methyl 2,4,6-Collidine
Olopatadine 2,5-Dimethylpyridine 2-Chloro-5-chloromethylpyridine 2,6-Lutidine METSULFURON METHYL
Kresoxim-methyl Dimethyl fumarate Methylparaben Bensulfuron methyl Betahistine dihydrochloride
Methyl salicylate Ferrous fumarate 2,2,6,6-Tetramethyl-4-piperidinol
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8-chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridyl)methyl]-4-piperidylidene]-5h-benzo[5,6]cyclohepta[1,2-b]pyridine 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]- 5H-benzo[5,6]cyclohepta[1,2-b]pyridine (2E)-2-Butenedioate Rupafi RUPATADINEFUMARATE(FORR&DONLY) RUPATADINE FREE BASE 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]- 5H-benzo[5,6]cyclohepta[1,2-β]pyridine (2E)-2-Butenedioate Rupafin Rupatadine fumarate 5H-Benzo(5,6)cyclohepta(1,2-B)pyridine, 8-chloro-6,11-dihydro-11-(1-((5-methyl-3-pyridinyl)methyl)-4-piperidinylidene)- Unii-2ae8m83G3e Rupatidine FuMerate Alergoliber Pafinur Rinialer Rupax 8-Chloro-11-(1-((5-methylpyridin-3-yl)methyl)piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclo Rupatadine fuMerate 8-Chloro-11-(1-((5-Methylpyridin-3-yl)Methyl)piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine UR-12592 8-Chloro-11-(1-((5-methylpyridin-3-yl)methyl)piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cy RUPATADINE 8-chloro-11-[1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene]-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine 8-Chloro-6,11-dihydro-11-[1-[(5-methyl-3-pyridinyl)methyl]-4-piperidinylidene]-5H-benzo[5,6]cyclohepta[1,2-b]pyridine ROPATADINE Rupatidine Rupatadine (UR-12592) Lupatadine in methanol 158876-82-5 C30H30ClN3O4 C26H26ClN3C4H4O4 API Heterocyclic Compounds Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Rupatadine Pharmaceutical material and intermeidates APIs