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Olopatadine

CAS No.: 113806-05-6

Chemical Name:: Olopatadine

Synonyms: (Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid;KW 4679;OLOPATADINE;propylidene);Olopatatadine;Olopatadine(W.S);Olopatadine 13CD3;Olopatadine HCl API;a-Hydroxy-Olopatadine;Olopatadine Impurity E

CBNumber:: CB0689142

Molecular Formula:: C21H23NO3

Molecular Weight:: 337.41

MOL File:: 113806-05-6.mol

MSDS File:: SDS

Modify Date:: 2024/6/7 16:07:22

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Olopatadine Properties

Melting point	188-189.5°
Boiling point	523.0±50.0 °C(Predicted)
Density	1?+-.0.06 g/cm3(Predicted)
storage temp.	Amber Vial, Refrigerator
solubility	Chloroform (Slightly, Heated), DMSO (Slightly)
form	Solid
pka	4.29±0.10(Predicted)
color	Pale Yellow to Pale Beige
Stability	Light Sensitive
CAS DataBase Reference	113806-05-6(CAS DataBase Reference)

Olopatadine Chemical Properties,Uses,Production

Description

Olopatadine belongs to a kind of antihistamine reagent. It is a relatively selective H1-receptor antagonist and can inhibit the histamine release process from the mast cell, subsequently leading to temporary relief on the negative symptoms associated with histamine. It is devoid of effects on alpha-adrenergic, dopamine and muscarinic type I and II receptors. Its 0.1% solution can be used for topical administration to the eyes. It is indicated for the treatment of itching associated with allergic conjunctivitis.

Uses

Olopatadine is a dual acting histamine H1-receptor antagonist and mast cell stabilizer. Antiallergic; antihistaminic.

References

https://www.drugbank.ca/drugs/DB00768
http://www.rxlist.com/patanol-drug/clinical-pharmacology.htm
https://en.wikipedia.org/wiki/Olopatadine

Olopatadine Preparation Products And Raw materials

Raw materials

n-Butyllithium Trifluoroacetic anhydride 1,2-Dibromoethane 4-Hydroxyphenylacetic acid Boron trifluoride diethyl etherate

SODIUM PERMANGANATE Phosphorus oxychloride Phthalide 3-Chloro-1-(N,N-dimethyl)propylamine Methyltriphenylphosphonium bromide

METHYL 2-(4-((2-BROMOBENZYL)OXY)PHENYL)ACETATE Benzeneacetic acid, 4-[(2-bromophenyl)methoxy]-3-iodo-, methyl ester Benzeneacetic acid, 4-[(2-bromophenyl)methoxy]-3-(4-hydroxy-1-butyn-1-yl)-, methyl ester Dibenz[b,e]oxepin-2-acetamide, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-, 4-methylbenzenesulfonate (1:1) UGDFSHGFPJSALM-OCKHKDLRSA-N

Isoxepac (Z)-11-(3-dimethylaminopropylidene)-6,11-dihydro-dibenz-[b,e]oxepine-2-acetic acid hydrobromide

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Preparation Products

Olopatadine Suppliers

Global( 147)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
PANCHSHEEL ORGANICS LTD	+91-9821053955 +91-9324201019	Mumbai, India	82	58	Inquiry
Glenmark Pharmaceuticals Limited	+912240189999	Maharashtra, India	93	58	Inquiry
Alfa Omega Pharma	+91-8050045945 +91-9972665399	Maharashtra, India	126	58	Inquiry
Bioaltus Laboratories Pvt Ltd	+91-2249744539 +91-9820139885	Maharashtra, India	34	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Manus Aktteva	+91 (79) 6512-3395	New Delhi, India	581	34	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Luna Chemical Industries Private Limited	08048372754Ext 585	Vadodara, India	22	58	Inquiry
Avyukta Pharmachem	08048372406Ext 416	Maharashtra, India	1	58	Inquiry

Supplier	Advantage
PANCHSHEEL ORGANICS LTD	58
Glenmark Pharmaceuticals Limited	58
Alfa Omega Pharma	58
Bioaltus Laboratories Pvt Ltd	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Manus Aktteva	34
CHEMSWORTH	30
CLEARSYNTH LABS LTD.	58
Luna Chemical Industries Private Limited	58
Avyukta Pharmachem	58

113806-05-6(Olopatadine)Related Search:

Dimethyl sulfoxide ETHANE Dimethyl carbonate Dimethyl disulfide Dimethyl sulfate

Dimethyl phthalate Dacthal Dimethyl fumarate 1-AdaMantanethylaMine Dimethyl ether

Betahistine dihydrochloride N,N-Dimethylformamide Olopatadine HCl Loratadine Tramadol hydrochloride

Sibutramine hydrochloride DOXEPIN 4-BENZYLOXYPHENYLACETIC ACID

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11-((z)-3-(dimethyl-amino)propylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid Olopatatadine KW 4679 Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)- Olopatadine & Olopatadine Hydrochloride a-Hydroxy-Olopatadine OLOPATADINE -2-(11-(3-(Dimethylamino) -6,11-dihydrodibenzo[b,e]oxepin-2-yl) propylidene) {(11Z)-11-[3-(diMethylaMino)propylidene]-6,11- dihydrodibenzo[b,e]oxepin-2-yl}acetic acid Olopatadine(W.S) Olopatadine Impurity E 2-[(11E)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid Olopatadine USP/EP/BP OlopatadineQ: What is Olopatadine Q: What is the CAS Number of Olopatadine Q: What is the storage condition of Olopatadine Olopatadine 13CD3 Olopatadine HCl API 2-Methyl-99-nitrobenzyl&chloride (Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid 113806-05-6 C21H23NO3 API Olopatadine