Olopatadine
- CAS No.
- 113806-05-6
- Chemical Name:
- Olopatadine
- Synonyms
- (Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid;KW 4679;OLOPATADINE;propylidene);Olopatatadine;Olopatadine(W.S);Olopatadine 13CD3;Olopatadine HCl API;a-Hydroxy-Olopatadine;Olopatadine Impurity E
- CBNumber:
- CB0689142
- Molecular Formula:
- C21H23NO3
- Molecular Weight:
- 337.41
- MOL File:
- 113806-05-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/7 16:07:22
| Melting point | 188-189.5° |
|---|---|
| Boiling point | 523.0±50.0 °C(Predicted) |
| Density | 1?+-.0.06 g/cm3(Predicted) |
| storage temp. | Amber Vial, Refrigerator |
| solubility | Chloroform (Slightly, Heated), DMSO (Slightly) |
| form | Solid |
| pka | 4.29±0.10(Predicted) |
| color | Pale Yellow to Pale Beige |
| Stability | Light Sensitive |
| CAS DataBase Reference | 113806-05-6(CAS DataBase Reference) |
Olopatadine Chemical Properties,Uses,Production
Description
Olopatadine belongs to a kind of antihistamine reagent. It is a relatively selective H1-receptor antagonist and can inhibit the histamine release process from the mast cell, subsequently leading to temporary relief on the negative symptoms associated with histamine. It is devoid of effects on alpha-adrenergic, dopamine and muscarinic type I and II receptors. Its 0.1% solution can be used for topical administration to the eyes. It is indicated for the treatment of itching associated with allergic conjunctivitis.
Uses
Olopatadine is a dual acting histamine H1-receptor antagonist and mast cell stabilizer. Antiallergic; antihistaminic.
References
https://www.drugbank.ca/drugs/DB00768
http://www.rxlist.com/patanol-drug/clinical-pharmacology.htm
https://en.wikipedia.org/wiki/Olopatadine
Olopatadine Preparation Products And Raw materials
Raw materials
n-Butyllithium
Trifluoroacetic anhydride
1,2-Dibromoethane
4-Hydroxyphenylacetic acid
Boron trifluoride diethyl etherate
SODIUM PERMANGANATE
Phosphorus oxychloride
Phthalide
3-Chloro-1-(N,N-dimethyl)propylamine
Methyltriphenylphosphonium bromide
METHYL 2-(4-((2-BROMOBENZYL)OXY)PHENYL)ACETATE
Benzeneacetic acid, 4-[(2-bromophenyl)methoxy]-3-iodo-, methyl ester
Benzeneacetic acid, 4-[(2-bromophenyl)methoxy]-3-(4-hydroxy-1-butyn-1-yl)-, methyl ester
Dibenz[b,e]oxepin-2-acetamide, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-, 4-methylbenzenesulfonate (1:1)
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Global( 156)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| PANCHSHEEL ORGANICS LTD | +91-9821053955 +91-9324201019 | Mumbai, India | 82 | 58 | Inquiry |
| Glenmark Pharmaceuticals Limited | +912240189999 | Maharashtra, India | 93 | 58 | Inquiry |
| Alfa Omega Pharma | +91-8050045945 +91-9972665399 | Maharashtra, India | 126 | 58 | Inquiry |
| Bioaltus Laboratories Pvt Ltd | +91-2249744539 +91-9820139885 | Maharashtra, India | 34 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| Luna Chemical Industries Private Limited | 08048372754Ext 585 | Vadodara, India | 22 | 58 | Inquiry |
| Avyukta Pharmachem | 08048372406Ext 416 | Maharashtra, India | 1 | 58 | Inquiry |
| Uni Trade Agencies | 08068442234Ext 578 | Mumbai, India | 10 | 58 | Inquiry |
113806-05-6(Olopatadine)Related Search:
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11-((z)-3-(dimethyl-amino)propylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid
Olopatatadine
KW 4679
Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-
Olopatadine & Olopatadine Hydrochloride
a-Hydroxy-Olopatadine
OLOPATADINE
-2-(11-(3-(Dimethylamino)
-6,11-dihydrodibenzo[b,e]oxepin-2-yl)
propylidene)
{(11Z)-11-[3-(diMethylaMino)propylidene]-6,11-
dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
Olopatadine(W.S)
Olopatadine Impurity E
2-[(11E)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid
Olopatadine USP/EP/BP
OlopatadineQ: What is
Olopatadine Q: What is the CAS Number of
Olopatadine Q: What is the storage condition of
Olopatadine
Olopatadine 13CD3
Olopatadine HCl API
2-Methyl-99-nitrobenzyl&chloride
(Z)-2-(11-(3-(Dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid
113806-05-6
C21H23NO3
API
Olopatadine