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Cloxacillin benzathine

CAS No.: 23736-58-5

Chemical Name:: Cloxacillin benzathine

Synonyms: Benzathine cloxacillin;microsterile;Unii-ac79L7pv2g;Benzathine salt;Einecs 245-855-2;Clozoprim penicillin;CLOXACILLIN BENZATHINE;Cloxacillin Bensathine;Phenylbutazone Impurity 32;Benzathine and Cloxacillin

CBNumber:: CB1400386

Molecular Formula:: C35H38ClN5O5S

Molecular Weight:: 676.23

MOL File:: 23736-58-5.mol

MSDS File:: SDS

Modify Date:: 2024/8/14 18:30:21

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Cloxacillin benzathine Properties

Melting point	>145°C (dec.)
storage temp.	Refrigerator
solubility	Methanol (Slightly, Sonicated), Water (Slightly)
form	Solid
color	White to Off-White
InChIKey	OUMOALQYXBRQFX-UDEWTJSRNA-N
SMILES	N([C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@]12[H])C(C1=C(ON=C1C1C=CC=CC=1Cl)C)=O.C(C1C=CC=CC=1)NCCNCC1C=CC=CC=1 \|&1:1,5,13,r\|
CAS DataBase Reference	23736-58-5

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H317-H334
Precautionary statements	P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
HS Code	2941106000

Cloxacillin benzathine Chemical Properties,Uses,Production

Description

Cloxacillin benzathine is a valuable half-synthesized antibiotic used in veterinary medicine to treat infections caused by Gram positive and Gram negative bacteria. Given its high bioactivity, this compound is generally used to prevent infection and treat bovine mastitis, one of the most common diseases in dairy animals. This chemical compound was usually crystallized by precipitation from solutions after the reaction of two raw materials. The SEM photos indicate that the products are general needle-like crystals with some aggregates among them[1-2].
Cloxacillin benzathine

Uses

Cloxacillin Benzathine is a salt of Cloxacillin is an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.

References

[1] J. Li, J. Wang, Y. Bao. “Effects of Sonocrystallization on the Crystal Size Distribution of Cloxacillin Benzathine Crystals.” Chemical Engineering Technology 36 8 (2013): 1341–1346.
[2] R. S. Araújo. “Cloxacillin benzathine-loaded polymeric nanocapsules: Physicochemical characterization, cell uptake, and intramammary antimicrobial effect.” Materials science engineering. C, Materials for biological applications 134 1 (2019): 110006.

Cloxacillin benzathine Preparation Products And Raw materials

Raw materials

Preparation Products

Cloxacillin benzathine Suppliers

Global( 115)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Aurobindo Pharma Limited	+914066725000	Telangana, India	112	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
OCEAN TRADING CORPORATION	+91(22) 24921669	New Delhi, India	6211	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	China	12584	58	Inquiry
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	China	5894	58	Inquiry
Henan Suikang Pharmaceutical Co.,Ltd.	+86-18239973690 +86-18239973690	China	311	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21661	55	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29899	58	Inquiry

Supplier	Advantage
Aurobindo Pharma Limited	58
CLEARSYNTH LABS LTD.	58
OCEAN TRADING CORPORATION	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Pharma Affiliates	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Henan Suikang Pharmaceutical Co.,Ltd.	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58

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CLOXACILLIN BENZATHINE 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2alpha,5alpha,6beta)]-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1) microsterile 4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 6-3-(2-chlorophenyl)-5-methyl-4-isoxazolylcarbonylamino-3,3-dimethyl-7-oxo-, (2S,5R,6R)-, compd. with N,N-bis(phenylmethyl)-1,2-ethanediamine (2:1) (2S-(2alpha,5alpha,6beta))-6-(((3-(2-Chlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1) 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((3-(2-chlorophenyl)-5-methyl-4-isoxazolyl)carbonyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta))-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1) Cloxacillin, N,N'-dibenzylethylendiamin-salz Einecs 245-855-2 Unii-ac79L7pv2g Cloxacillin Benzathine (200 mg) Cloxacillin Bensathine Benzathine salt 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-(2-chlorophenyl)-5-methyl-4-isoxazolyl]carbonyl]amino]-3,3-dimethyl-7-oxo-, [2S-(2α,5α,6β)]-, compd. with N,N'-bis(phenylmethyl)-1,2-ethanediamine (2:1) Cloxacillin Benzathine (2:1) Cloxacillin benzathine USP/EP/BP Cloxacillin benzathine Vet pharma use 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[3-... Cloxacillin Benzathine (1141909) Benzathine cloxacillin Clozoprim penicillin Phenylbutazone Impurity 32 Benzathine and Cloxacillin Chloramphenicol penicillin 23736-58-5 23736-58-8 2C19H18ClN3O5SC16H20N2 C19H17ClN3O5SC16H20N2Na C54H56Cl2N8O10S2 API