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Tetrakis(hydroxymethyl)phosphonium chloride

Tetrakis(hydroxymethyl)phosphonium chloride  Structure
CAS No.
124-64-1
Chemical Name:
Tetrakis(hydroxymethyl)phosphonium chloride
Synonyms
THPC;SQJGLHL;THPS-UPC;meso-THPC;pyrosettkc;nci-c55061;AURORA KA-1157;HISHICOLIN THPC;tetramethylolphosphonium chloride;tetrakis(hydroxymethyl)phosphonium
CBNumber:
CB2166508
Molecular Formula:
C4H12ClO4P
Molecular Weight:
190.56
MOL File:
124-64-1.mol
MSDS File:
SDS
Modify Date:
2024/7/29 18:03:56

Tetrakis(hydroxymethyl)phosphonium chloride Properties

Melting point 154°C
Boiling point 115°C/760mmHg
Density 1.341 g/mL at 25 °C
vapor pressure 0Pa at 25℃
refractive index n20/D 1.512
pka 6.05[at 20 ℃]
form Solution
color Clear light pink or yellow-green
Water Solubility >=10 g/100 mL at 20 ºC
BRN 3631669
InChI InChI=1S/C4H12O4P.ClH/c5-1-9(2-6,3-7)4-8;/h5-8H,1-4H2;1H/q+1;/p-1
InChIKey AKXUUJCMWZFYMV-UHFFFAOYSA-M
SMILES [P+](CO)(CO)(CO)CO.[Cl-]
LogP -9.8
CAS DataBase Reference 124-64-1(CAS DataBase Reference)
EPA Substance Registry System Tetrakis(hydroxymethyl)phosphonium chloride (124-64-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H290-H301+H311-H314-H317-H360FD-H410
Precautionary statements  P201-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  T,N
Risk Statements  21-25-38-41-42/43-51/53
Safety Statements  22-26-36/37/39-45-60-61-23
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
RTECS  TA2450000
HazardClass  8
PackingGroup  III
HS Code  29319019
Toxicity mammal (species unspecified),LD50,oral,400mg/kg (400mg/kg),Kobunshi. High Polymers. Vol. 24, Pg. 788, 1975.
NFPA 704
1
3 0

Tetrakis(hydroxymethyl)phosphonium chloride price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 404861 Tetrakis(hydroxymethyl)phosphonium chloride solution 80% in H2O 124-64-1 100ML ₹7923.9 2022-06-14 Buy
Sigma-Aldrich(India) 404861 Tetrakis(hydroxymethyl)phosphonium chloride solution 80% in H2O 124-64-1 500ML ₹14916.85 2022-06-14 Buy
Product number Packaging Price Buy
404861 100ML ₹7923.9 Buy
404861 500ML ₹14916.85 Buy

Tetrakis(hydroxymethyl)phosphonium chloride Chemical Properties,Uses,Production

Chemical Properties

Clear light pink or yellow-green solution

Uses

Tetrakis(hydroxymethyl)phosphonium chloride solution (80% in H2O) has been used as a reducing agent and stabilizing ligand for the synthesis of gold nanoparticles (AuNPs) from gold(III) chloride trihydrate (HAuCl4.3H2O). It is a tetra-functional, amine-reactive, aqueous crosslinker that can be used for tuning the properties of protein-based hydrogels for 3D cell encapsulation applications.

Definition

A crystalline compound made by the reaction of phosphine, formaldehyde, and hydrochloric acid.

General Description

Clear slightly viscous,colorless to yellow liquid (20% H2O solution).

Air & Water Reactions

Hygroscopic. Water soluble.

Reactivity Profile

Tetrakis(hydroxymethyl)phosphonium chloride reacts vigorously with oxidizers and alkalis. Reacts with cellulose.

Health Hazard

ACUTE/CHRONIC HAZARDS: Tetrakis(hydroxymethyl)phosphonium chloride may be corrosive. When heated to decomposition, it may emit very toxic fumes of POx, hydrogen chloride and bis(chloromethyl)ether. Decomposition of Tetrakis(hydroxymethyl)phosphonium chloride in an aqueous environment may produce phosphine, formaldehyde and hydrogen chloride.

Fire Hazard

Tetrakis(hydroxymethyl)phosphonium chloride is probably combustible.

Purification Methods

Crystallise it from AcOH and dry it at 100o in a vacuum. An 80% w/v aqueous solution has d4 1.33 [Reeves J Am Chem Soc 77 3923 1955]. [Beilstein 1 IV 3062.]

Tetrakis(hydroxymethyl)phosphonium chloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 255)Suppliers
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GLR Innovations +91 9891111994 New Delhi, India 4542 58 Inquiry
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