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Vatalanib base

Vatalanib base Structure
CAS No.
212141-54-3
Chemical Name:
Vatalanib base
Synonyms
VataL;VATALANIB;PTK787 2HCl;VATALANIB BASE;Vatalanib 2HCL;PTK787 free base;PTK/ZK free base;Vatalanib (PTK787);anib (PTK787) 2HCL;CGP-79787 free base
CBNumber:
CB2173616
Molecular Formula:
C20H15ClN4
Molecular Weight:
346.81
MOL File:
212141-54-3.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:03
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Vatalanib base Properties

Melting point 209-212°
Boiling point 587.8±50.0 °C(Predicted)
Density 1.330±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic
form solid
pka 5.46±0.10(Predicted)
color Light yellow to yellow

SAFETY

Risk and Safety Statements

HS Code  2933399990

Vatalanib base Chemical Properties,Uses,Production

Uses

Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.

Definition

ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.

Vatalanib base Preparation Products And Raw materials

Raw materials

Pyridine, 4-(bromomethyl)- (9CI) 4-(Chloromethyl)pyridine 1-CHLORO-4-(4-PYRIDINYLMETHYL)PHTHALAZINE 4-(4-PYRIDYLMETHYL)-1(2H)-PHTALAZINONE 3-HYDROXY-2-PYRIDIN-4-YL-INDEN-1-ONE
Phthalide 1-Chloro-4-iodobenzene 4-Chlorobenzenamine hydrochloride Phthalonitrile 4-Chloroaniline
4-Bromochlorobenzene
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Preparation Products

Vatalanib base Suppliers

Global( 116)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
KKyemistry (India) Pvt. Ltd. +91 (40) 2351-0950 New Delhi, India 197 50 Inquiry
Trignokem International +91 (40) 2717-0709 New Delhi, India 380 50 Inquiry
Manus Aktteva +91 (79) 6512-3395 New Delhi, India 581 34 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Supplier Advantage
KKyemistry (India) Pvt. Ltd. 50
Trignokem International 50
Manus Aktteva 34
CLEARSYNTH LABS LTD. 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Capot Chemical Co.,Ltd. 60
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
CONIER CHEM AND PHARMA LIMITED 58
career henan chemical co 58

Vatalanib base Spectrum

Vatalanib base(212141-54-3)1HNMR

212141-54-3(Vatalanib base)Related Search:

Chlorodimethylphenylsilane Trimethylphenylammonium chloride 4-Methylpyridine 2,6-Lutidine 2-Chloro-5-chloromethylpyridine
Triethanolamine Dibenzylamine Bis(2-ethylhexyl)amine 2,4,6-Collidine Triallylamine
Azamethiphos Vatalanib Dihydrochloride 4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID AMIDE 4-(4-AMINOPHENOXY)PYRIDINE Sorafenib
4-(4-Aminophenoxy)-N-methylpicolinamide Vatalanib base
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N-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine N-(4-Chlorophenyl)-4-(4-pyridinylmethyl)- 1-Phthalazinamine 1-PhthalazinaMine, N-(4-chlorophenyl)-4-(4-pyridinylMethyl)- Vatalanib (PTK787) Dihydrochloride Base Pynasunate, ZK222584, CGP-79787, PTK 787 (4-Chloro-phenyl)-(4-pyridin-4-ylmethyl-phthalazin-1-yl)-amine Vatalanib (free base) VATALANIB SORAFENIB BASE VATALANIB Vatalanib 2HCL VATALANIB BASE Vatalanib free base (PTK787 free base PTK787 free base PTK787 FREE BASE; PTK/ZK FREE BASE; CGP-79787 FREE BASE; ZK-222584 FREE BASE CGP-79787 free base PTK/ZK free base ZK-222584 free base) PTK787 2HCl ZK 222584 (CPG-79787) 2HCL;PTK787 2HCL Vatalanib (PTK787) anib (PTK787) 2HCL VataL 212141-54-3 Antineoplastic