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Cefozopran

CAS No.: 113359-04-9

Chemical Name:: Cefozopran

Synonyms: D01052;Firstci;sce2787;SCE-1787;Firstcin);CEFOZOPRAN;Cefozopran (inn);SCE2787;SCE 2787;SCE-2787：Fastocin;Cefozopran(SCE 2787)

CBNumber:: CB2198495

Molecular Formula:: C19H17N9O5S2

Molecular Weight:: 515.52

MOL File:: 113359-04-9.mol

MSDS File:: SDS

Modify Date:: 2023/5/21 10:59:17

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Cefozopran Properties

Melting point	>300°C
storage temp.	Store at -20°C
solubility	Soluble in DMSO
CAS DataBase Reference	113359-04-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H334-H317
Precautionary statements	P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501

Cefozopran Chemical Properties,Uses,Production

Chemical Properties

White To Pale-Yellow Powder

Uses

Antibacterial

Antimicrobial activity

An aminothiazole cephalosporin formulated as the hydrochloride. Activity is similar to that of ceftazidime, but it is more active against methicillin-susceptible staphylococci (MIC 1 mg/L). Representative MICs against Gram-negative species are: Esch coli 0.25 mg/L; K. pneumoniae 1 mg/L; Ps. aeruginosa 1–8 mg/L. Activity against Acinetobacter spp., Sten. maltophilia and B. fragilis group is poor.
A 20-min infusion of 1.5 g achieved a plasma concentration of around 125 mg/L at the end of infusion. Almost 90% of the dose was excreted in the urine over 24 h. The mean terminal half-life was around 2 h. Adverse reactions appear to be typical of those of other group 6 cephalosporins.
It is available in Japan.

Cefozopran Preparation Products And Raw materials

Raw materials

2-Mercapto-5-methyl-1,3,4-thiadiazole Hexane Potassium iodide 2-Butanone Trifluoroacetic acid

Pyridazine Phosphorus pentachloride Ethyl acetate Dichloromethane Formamide

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Preparation Products

Cefozopran Suppliers

Global( 115)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Venkatasai Life Sciences	+91-9908134868 +91-8008303069	Hyderabad, India	186	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
SIMAGCHEM CORP	+86-13806087780	China	17367	58	Inquiry
Hubei Ipure Biology Co., Ltd	+8613367258412	China	10326	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	China	9030	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418684 +8618949823763	China	25363	58	Inquiry

Supplier	Advantage
Venkatasai Life Sciences	58
SynZeal Research Pvt Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
SIMAGCHEM CORP	58
Hubei Ipure Biology Co., Ltd	58
Career Henan Chemica Co	58
Shaanxi Dideu Medichem Co. Ltd	58
BOC Sciences	58
Zhejiang J&C Biological Technology Co.,Limited	58
Hefei TNJ Chemical Industry Co.,Ltd.	58

113359-04-9(Cefozopran)Related Search:

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Tris(hydroxymethyl)aminomethane DIACETAMIDE Cefazolin 2,1,3-Benzothiadiazole Acetaminophen

2-Mercapto-5-methyl-1,3,4-thiadiazole Cefotetan 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-quinolinium inner salt

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CEFOZOPRAN sce2787 1-[[(6R,7R)-7-[[(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-imidazo[1,2-b]pyridazinium hydroxide inner salt 1-[[(6R,7R)-7-[[2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]imidazo[1,2-b]pyridazinium Inner Salt Firstci SCE-1787 Cefozopran (inn) D01052 Firstcin) SCE-2787：Fastocin (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Parent nucleus of Cefozopran SCE2787;SCE 2787 Cefozopran(SCE 2787) Cefozopran USP/EP/BP 113359-04-9 C19H17N9O5S2 C19H18ClN9O5S2 Antibacterial Intermediates & Fine Chemicals Pharmaceuticals Cefozopran Hydrochloride and its intermediates