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Ethyl bromodifluoroacetate

Ethyl bromodifluoroacetate Structure
CAS No.
667-27-6
Chemical Name:
Ethyl bromodifluoroacetate
Synonyms
2-broMo-2,2-difluoroacetate;EBDA;2-Bromo-2,2-difluoroacetic acid ethyl ester;EBFA;bromodifL;Ethyl bromodifluoroa;Ethylbromdifluoracetat;Twoethyl broMidefluoride;ETHYL BROMODIFLUOROACETATE;difluorobromo ethyl acetate
CBNumber:
CB2238865
Molecular Formula:
C4H5BrF2O2
Molecular Weight:
202.98
MOL File:
667-27-6.mol
MSDS File:
SDS
Modify Date:
2024/8/24 19:19:26

Ethyl bromodifluoroacetate Properties

Boiling point 112 °C/700 mmHg (lit.)
Density 1.583 g/mL at 25 °C (lit.)
refractive index n20/D 1.387(lit.)
Flash point 70 °F
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Soluble in most organic solvents.
form Liquid
Specific Gravity 1.583
color Clear colorless to slightly yellow
BRN 1906095
InChI InChI=1S/C4H5BrF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
InChIKey IRSJDVYTJUCXRV-UHFFFAOYSA-N
SMILES C(OCC)(=O)C(Br)(F)F
CAS DataBase Reference 667-27-6(CAS DataBase Reference)
NIST Chemistry Reference Ethyl bromodifluoroacetate(667-27-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS05
Signal word  Danger
Hazard statements  H225-H314
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  C,F,Xi
Risk Statements  10-34-36
Safety Statements  26-36/37/39-45-16-27
RIDADR  UN 2924 3/PG 2
WGK Germany  3
Hazard Note  Irritant/Flammable
TSCA  No
HazardClass  3
PackingGroup  II
HS Code  29159000
NFPA 704
3
3 0

Ethyl bromodifluoroacetate price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 295795 Ethyl bromodifluoroacetate 98% 667-27-6 5G ₹5044.45 2022-06-14 Buy
TCI Chemicals (India) B1463 Ethyl Bromodifluoroacetate min. 98.0 % 667-27-6 5G ₹3400 2022-05-26 Buy
TCI Chemicals (India) B1463 Ethyl Bromodifluoroacetate min. 98.0 % 667-27-6 25G ₹9400 2022-05-26 Buy
TCI Chemicals (India) B1463 Ethyl Bromodifluoroacetate min. 98.0 % 667-27-6 250G ₹23400 2022-05-26 Buy
Product number Packaging Price Buy
295795 5G ₹5044.45 Buy
B1463 5G ₹3400 Buy
B1463 25G ₹9400 Buy
B1463 250G ₹23400 Buy

Ethyl bromodifluoroacetate Chemical Properties,Uses,Production

Description

Ethyl bromodifluoroacetate, a clear to yellow liquid, is an ester of bromodifluoroacetic acid and ethyl alcohol. It is an ester that can be used to introduce the CF2 group when synthesizing chemical compounds. Ethyl bromdifluoroacetate is considered to be a good compound in the generation of compounds and for testing with other organic compounds like lactones, imines, and other amino acids.

Chemical Properties

clear colorless to slightly yellow liquid

Uses

Ethyl bromodifluoroacetate is usually used in the preparation of substituted ethyl 2′-pyridyldifluoroacetates,4-alkoxymethyl- and 4-aryloxymethyl-3,3-difluoropiperidines,α,α-difluoro-β-lactams,mono- and difluoromethylated phenanthridine derivatives.

Preparation

Difluorobromoacetonitrile is taken as a raw material, and prepared through a one-pot method and subjected to alcoholysis and esterification in ethanol aqueous solution to obtain ethyl bromodifluoroacetate.Reaction equation is:
BrF2CCN→BrF2CCOOH→BrF2CCOOC2H5

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TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
ETHYL BROMODIFLUOROACETATE BROMODIFLUOROACETIC ACID ETHYL ESTER Difluorobromoacetic acid ethyl ester Ethyl 2,2-Difluoro-2-Bromoac Ethyl bromodifluoroa 2-Bromo-2,2-difluoro-1-ethoxyethan-1-one, 2-Bromo-2,2-difluoro-1-ethoxy-1-oxoethane Ethyl broModifluoroacetate, 98% 5GR 2-Bromo-2,2-difluoro-1-ethoxyethan-1-one, 2-Bromo-2,2-difluoro-1-ethoxy-1-oxoethane, Bromo(difluoro)acetic acid ethyl ester Twoethyl broMidefluoride Ethyl broMoacetatetwo fluorine Acetic acid, bromodifluoro-, ethyl ester 2,2-difluoro-2-bromoacetate ethyl Ethyl bromodifluoroacetate 98% difluorobromo ethyl acetate Ethylbromodifluoroacetate98% Acetic acid, 2-bromo-2,2-difluoro-, ethyl ester Ethyl 2,2-difluoro-2-bromoacetate Ethylbromdifluoracetat Ethyl Bromodifluoroacetate > Ethyl Bromodifluoroacetate,99% bromodifL TIANFU CHEM---Ethyl bromodifluoroacetate 2-Bromo-2,2-difluoroacetic acid ethyl ester 2-broMo-2,2-difluoroacetate EBDA Ethyl bromoacetate difluoro EBFA 667-27-6 C4H5BrF2O2 BrCF2COOCH2CH3 BrCF2CO2CH2CH3 Esters Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Organic Building Blocks Building Blocks C2 to C5 Carbonyl Compounds Fluorinated Building Blocks Alkyl Fluorinated Building Blocks Building Blocks C2 to C5 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks C2 to C5 Carbonyl Compounds Esters API intermediates Fluorinated Building Blocks Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds Synthetic Organic Chemistry Fluoro series Pharmaceutical Intermediates Fluoro-containing compounds