Vonoprazan
- CAS No.
- 881681-00-1
- Chemical Name:
- Vonoprazan
- Synonyms
- 1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;Vonoprazan;Vonoprazan-025;TAK-438 (free base);Vonoprazan USP/EP/BP;TAK438 Intermediate 6;Vonoprazan Impurity 133;Vonoprazan Impurity 132;Vonoprazan Impurity 134;Vonoprazan Impurity 135
- CBNumber:
- CB22716734
- Molecular Formula:
- C17H16FN3O2S
- Molecular Weight:
- 345.39
- MOL File:
- 881681-00-1.mol
- Modify Date:
- 2023/9/15 18:01:53
| Boiling point | 530.3±60.0 °C(Predicted) |
|---|---|
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 9.06±0.10(Predicted) |
| form | Solid |
| color | Pale Yellow to Light Yellow |
| Stability | Hygroscopic |
| InChI | InChI=1S/C17H16FN3O2S/c1-19-10-13-9-17(15-6-2-3-7-16(15)18)21(12-13)24(22,23)14-5-4-8-20-11-14/h2-9,11-12,19H,10H2,1H3 |
| InChIKey | BFDBKMOZYNOTPK-UHFFFAOYSA-N |
| SMILES | N1(S(C2=CC=CN=C2)(=O)=O)C(C2=CC=CC=C2F)=CC(CNC)=C1 |
| CAS DataBase Reference | 881681-00-1 |
Vonoprazan Chemical Properties,Uses,Production
Uses
Vonoprazan is used to treat an infection caused by the bacteria H. pylori. This bacteria can cause stomach/intestinal ulcers and irritation/swelling of the lining of the stomach. It may also increase the risk of stomach cancer. Treating the infection will help the ulcers get better and reduces the risk of serious damage to the lining of the stomach/intestines (such as bleeding, tearing).Vonoprazan is an acid blocker. It works by blocking acid production in the stomach. Decreasing excess stomach acid can help ulcers heal. Amoxicillin is an antibiotic used to treat a wide variety of bacterial infections (including H. pylori). Treating the infection helps the ulcers heal and reduces the risk of ulcers returning. Amoxicillin is a penicillin-type antibiotic. It works by stopping the growth of bacteria. Amoxicillin treats only bacterial infections. It will not work for viral infections (such as common cold, flu).
Side effects
Vonoprazan may cause any of the following side effects: diarrhoea, constipation, nausea, stomach discomfort, bloatedness, changes in taste, and rash. Some side effects may need immediate medical help.
Vonoprazan Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Honour Lab Limited | +919845977466 | Telangana, India | 164 | 58 | Inquiry |
| Anlon Healthcare Pvt Ltd | +91-2812562538 +91-7069690081 | Gujarat, India | 54 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Senova Technology Co. Ltd. | +86-0755-86703119 +8618503098836 | China | 350 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| SHANDONG BOYUAN PHARMACEUTICAL CO., LTD. | +86-0531-69954981 +8615666777973 | China | 211 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21676 | 55 | Inquiry |
Related articles
- Uses and Mechanism of Vonoprazan
- Vonoprazan (trade name Takecab) is a first-in-class potassium-competitive acid blocker. It was approved in the Japanese market....
- May 10，2022
881681-00-1(Vonoprazan)Related Search:
1of4
chevron_right