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PD0332991 Isethionate

CAS No.: 827022-33-3

Chemical Name:: PD0332991 Isethionate

Synonyms: CS-1265;PD332991;PD 332991;PD-332991;PF 00080665-73;PD 0332991-0054;PD0332991 Isethiote;Palbociclib-019-Salt;PD0332991 Isethionate;Palbociclib (isethionate)

CBNumber:: CB02663078

Molecular Formula:: C26H35N7O6S

Molecular Weight:: 573.67

MOL File:: 827022-33-3.mol

MSDS File:: SDS

Modify Date:: 2024/6/4 15:29:52

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PD0332991 Isethionate Properties

storage temp.	room temp
solubility	≥28.7 mg/mL in DMSO; insoluble in EtOH; ≥26.8 mg/mL in H2O
form	powder
color	white to beige
CAS DataBase Reference	827022-33-3

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301+P310
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

PD0332991 Isethionate price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	PZ0199	PD 0332991 isethionate ≥98% (HPLC)	827022-33-3	5MG	₹12297.2	2022-06-14	Buy
Sigma-Aldrich(India)	PZ0199	PD 0332991 isethionate ≥98% (HPLC)	827022-33-3	25MG	₹50076.45	2022-06-14	Buy

Product number	Packaging	Price	Buy
PZ0199	5MG	₹12297.2	Buy
PZ0199	25MG	₹50076.45	Buy

PD0332991 Isethionate Chemical Properties,Uses,Production

Uses

PD 0332991 isethionate has been used:

to incubate MCF10A cells to verify cyclin D1 inhibition of autophagy involved cyclin-dependent kinase activity
as a cyclin dependent kinase 4 (CDK4) inhibitor to study its anticonvulsive property in Drosophila
to mimic the inhibitory effect of 5α-dihydrotestosterone (DHT) on HPr-1AR cell cycle progression and growth

Biochem/physiol Actions

PD 0332991 is a potent selective inhibitor of cyclin dependent kinases CDK4 and CDK6 with in vitro IC50 = 11 nM (CDK4) and 16 nM (CDK6). PD 0332991 induces G1 arrest in retinoblastoma (Rb)-positive tumor cells.

PD0332991 Isethionate Preparation Products And Raw materials

Raw materials

Preparation Products

PD0332991 Isethionate Suppliers

Global( 175)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9337	55	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29898	58	Inquiry
BOC Sciences	+1-631-485-4226	United States	19553	58	Inquiry
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	China	23556	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	25247	58	Inquiry
Finetech Industry Limited	+86-27-87465837 +8618971612321	China	9624	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
Wuhan Godbullraw Chemical Co.,ltd	+undefined18986288449	China	560	58	Inquiry

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
BOC Sciences	58
ANHUI WITOP BIOTECH CO., LTD	58
Dideu Industries Group Limited	58
Finetech Industry Limited	58
InvivoChem	58
Wuhan Godbullraw Chemical Co.,ltd	58

PD0332991 Isethionate Spectrum

PD0332991 Isethionate(827022-33-3)¹HNMR

827022-33-3(PD0332991 Isethionate)Related Search:

4-[6-(6-BROMO-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDRO-PYRIDO[2,3-D]PYRIMIDIN-2-YLAMINO)-PYRIDIN-3-YL]-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER Vonoprazan FuMarate Paroxetine Vonoprazan fumarate Vonoprazan

paroxetine Mesylate Rivaroxaban Potassium pyrophosphate MK-2206 2HCl Ribociclib

Trametinib ABT 263 Abemaciclib mesylate (LY2835219) Olaparib Roscovitine

tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate PD 0332991 HCl BML-259

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PD0332991 Isethionate Palbociclib (PD0332991) Isethionate Palbociclib (isethionate) PD 0332991-0054 PF 00080665-73 Ethanesulfonic acid, 2-hydroxy-, compd. with 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one (1:1) PD0332991 Isethiote 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxyethanesulfonate Ethanesulfonic acid, 2-hydroxy-, compd. with 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidi palbociclib Isethionate 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one mono-isethionate salt Palbociclib-019-Salt Palbociclib Isethionate(PD0332991) 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one,2-hydroxyethanesulfonic acid Palbociclib Isethionate, brand name: Ibrance PD 0332991; PD-0332991; PD0332991; PD0332991; PD332991; PD-332991; PD 332991; PALBOCICLIB ISETHIONATE, BRAND NAME: IBRANCE PD 332991 PD332991 PD-332991 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one isethionate salt CS-1265 Palbociclib-isethionate, PD0332991 isethionate Palbociclib impurity 20/Palbociclib Isethionate/6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one,2-hydroxyethanesulfonic acid PD 0332991 (Palbociclib) Isethionate PD 0332991 Isethionate x PD0332991 Isethionate USP/EP/BP PD 0332991 Isethionate DISCONTINUED Palbociclib (PD0332991) Isethionate|||PD 0332991 isethionate 827022-33-3 C26H35N7O6S C24H29N7O2C2H6O4S Inhibitors APIs