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ChemicalBook > Product Catalogue >Biochemical Engineering >Inhibitors >Cell Cycle >CDK inhibitors >PD0332991 Isethionate

PD0332991 Isethionate

PD0332991 Isethionate Structure
  • ₹12297.2 - ₹50076.45
  • Product name: PD0332991 Isethionate
  • CAS: 827022-33-3
  • MF: C26H35N7O6S
  • MW: 573.67
  • EINECS:804-556-2
  • MDL Number:MFCD22666589
  • Synonyms:PD0332991 Isethionate;Palbociclib (PD0332991) Isethionate;Palbociclib (isethionate);PD 0332991-0054;PF 00080665-73;Ethanesulfonic acid, 2-hydroxy-, compd. with 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one (1:1);PD0332991 Isethiote;6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one 2-hydroxyethanesulfonate
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberPZ0199
  • Product descriptionPD 0332991 isethionate ≥98% (HPLC)
  • Packaging5MG
  • Price₹12297.2
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberPZ0199
  • Product descriptionPD 0332991 isethionate ≥98% (HPLC)
  • Packaging25MG
  • Price₹50076.45
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) PZ0199 PD 0332991 isethionate ≥98% (HPLC) 5MG ₹12297.2 2022-06-14 Buy
Sigma-Aldrich(India) PZ0199 PD 0332991 isethionate ≥98% (HPLC) 25MG ₹50076.45 2022-06-14 Buy

Properties

storage temp. :room temp
solubility :≥28.7 mg/mL in DMSO; insoluble in EtOH; ≥26.8 mg/mL in H2O
form :powder
color :white to beige
CAS DataBase Reference :827022-33-3

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

PD 0332991 isethionate has been used:
  • to incubate MCF10A cells to verify cyclin D1 inhibition of autophagy involved cyclin-dependent kinase activity
  • as a cyclin dependent kinase 4 (CDK4) inhibitor to study its anticonvulsive property in Drosophila
  • to mimic the inhibitory effect of 5α-dihydrotestosterone (DHT) on HPr-1AR cell cycle progression and growth


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