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TYRPHOSTIN B7

TYRPHOSTIN B7 Structure
CAS No.
134036-53-6
Chemical Name:
TYRPHOSTIN B7
Synonyms
AG 370;TYRPHOSTIN B7;TYRPHOSTIN AG 370;TYROPHOSTIN AG 370;2-AMINO-4-(1H-INDOL-5-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE;2-AMINO-4-(1H-INDO-5'-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE;3-AMINO-4-(1H-INDOL-5-YLMETHYLENE)-2-PENTENETRICARBONITRILE;2-Pentenetricarbonitrile, 3-amino-4-(1H-indol-5-ylmethylene)-;2-Amino-4-(1H-indo-5μ-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7
CBNumber:
CB2288901
Molecular Formula:
C15H9N5
Molecular Weight:
259.27
MOL File:
134036-53-6.mol
Modify Date:
2023/5/18 11:31:14
Request For Quotation

TYRPHOSTIN B7 Properties

Boiling point 714.1±60.0 °C(Predicted)
Density 1.396±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO: soluble
form Yellow solid.
pka 15.95±0.30(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

TYRPHOSTIN B7 Chemical Properties,Uses,Production

Description

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which selectively inhibit PTKs of key growth factors such as epidermal growth factor (EGF) or platelet-derived growth factor (PDGF) by blocking the phosphorylation of specific tyrosine residues. AG-370 is a selective inhibitor of PDGF receptor kinase with an IC50 value of 20 μM in human bone marrow fibroblasts. It displays comparatively weak inhibition of the EGF receptor (IC50 = 820 μM).

TYRPHOSTIN B7 Preparation Products And Raw materials

Raw materials

Preparation Products

TYRPHOSTIN B7 Suppliers

Global( 36)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9806 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24647 58 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
Spectrum Chemicals & Laboratory Products 310 516 8000 United States 6706 77 Inquiry
MP Biomedicals, Inc. 949 833 2500 United States 6566 81 Inquiry
BIOMOL INTERNATIONAL, LP (800) 942-0430 United States 1503 77 Inquiry
Alexis Corporation +41 61 926 8989 Switzerland 3599 74 Inquiry
A.G. Scientific, Inc. 858 452 9925 United States 1066 71 Inquiry
Fluorochem Ltd (01457) 868921 (4 lines) United Kingdom 6383 65 Inquiry
Supplier Advantage
Aladdin Scientific 58
Shanghai EFE Biological Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
VWR International 82
Spectrum Chemicals & Laboratory Products 77
MP Biomedicals, Inc. 81
BIOMOL INTERNATIONAL, LP 77
Alexis Corporation 74
A.G. Scientific, Inc. 71
Fluorochem Ltd 65

134036-53-6(TYRPHOSTIN B7)Related Search:

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AG 370 2-Amino-4-(1H-indo-5μ-yl)-1,1,3-tricyanobuta-1,3-diene, Tyrphostin B7 TYROPHOSTIN AG 370 TYRPHOSTIN B7 TYRPHOSTIN AG 370 3-AMINO-4-(1H-INDOL-5-YLMETHYLENE)-2-PENTENETRICARBONITRILE 2-AMINO-4-(1H-INDO-5'-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE 2-AMINO-4-(1H-INDOL-5-YL)-1,1,3-TRICYANOBUTA-1,3-DIENE 2-Pentenetricarbonitrile, 3-amino-4-(1H-indol-5-ylmethylene)- 134036-53-6 Platelet Derived Growth Factor Receptor (PDGFR) Receptor Tyrosine Kinase Inhibitors Kinase/Phosphatase Biology Cell Signaling and Neuroscience Cell Biology BioChemical