6-Aminofluorescein
- CAS No.
- 51649-83-3
- Chemical Name:
- 6-Aminofluorescein
- Synonyms
- 6-AF;6-AFM;(isoMer II);6-AMINOFLUORESCEIN;6-AMinofluorescein 6-Aminofluorescein (6-AF);AMINOFLUORESCEIN ISOMER II;FLUORESCEINAMINE, ISOMER 2;FLUORESCEINMINE, ISOMER 2,;FLUORESCEINAMINE, ISOMER II
- CBNumber:
- CB2300526
- Molecular Formula:
- C20H13NO5
- Molecular Weight:
- 347.32
- MOL File:
- 51649-83-3.mol
- Modify Date:
- 2024/4/24 17:21:45
| Melting point | 285 °C (dec.)(lit.) |
|---|---|
| Boiling point | 481.89°C (rough estimate) |
| Density | 1.3724 (rough estimate) |
| refractive index | 1.5180 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: soluble1mg/mL, clear, yellow to very dark yellow-orange |
| pka | 9.34±0.20(Predicted) |
| form | Solid |
| color | Yellow to Orange |
| BRN | 51708 |
| Stability | Light and Moisture Sensitive |
| InChI | InChI=1S/C20H13NO5/c21-10-1-4-13-16(7-10)20(26-19(13)24)14-5-2-11(22)8-17(14)25-18-9-12(23)3-6-15(18)20/h1-9,22-23H,21H2 |
| InChIKey | YOAWSYSKQHLFPM-UHFFFAOYSA-N |
| SMILES | C12(C3=C(C=C(O)C=C3)OC3=C1C=CC(O)=C3)C1=C(C=CC(N)=C1)C(=O)O2 |
| CAS DataBase Reference | 51649-83-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-23 | |||||||||
| HS Code | 29329990 | |||||||||
| NFPA 704 |
|
6-Aminofluorescein price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 201634 | 6-Aminofluorescein | 51649-83-3 | 250MG | ₹17271.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 201634 | 6-Aminofluorescein | 51649-83-3 | 1G | ₹44289 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 07985 | 6-Aminofluorescein suitable for fluorescence, BioReagent, ~95% (HPLC) | 51649-83-3 | 1G | ₹17082.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 07985 | 6-Aminofluorescein suitable for fluorescence, BioReagent, ~95% (HPLC) | 51649-83-3 | 5G | ₹60162 | 2022-06-14 | Buy |
| TCI Chemicals (India) | A0864 | 6-Aminofluorescein (isomer II) | 51649-83-3 | 1G | ₹15000 | 2022-05-26 | Buy |
6-Aminofluorescein Chemical Properties,Uses,Production
Description
6-Aminofluorescein (6-AF) is a new fluorescence dye with bright colors and high fluorescence intensity. Its chemical structure history contains a nitrogen group and a fluorescent group. The presence of the fluorescent component enables 6-Aminofluorescein to emit a distinct fluorescent signal when excited, making it valuable for fluorescent labeling and imaging. It is widely used in biological science research, chemical analysis and fluorescence microscopy.
Chemical Properties
Yellow Solid
Uses
Fluorescent labeling reagent for proteins. Glycosaminoglycuronans react with 6-aminofluorescein to yield fluorescent derivatives. Used in the fluorescent antibody technique for rapid identification of pathogens.
Biological Functions
6-Aminofluorescein has been demonstrated to be useful fluorescent labeling reagent for fullerene-based liposome nanostructures termed "buckysomes". 6-aminofluorescein dissolved in 0.1 N NaOH can be quantified from a maximum absorbance at 490 nm. Decarboxylated 6-aminofluorescein dissolved 6 N HCl (prepare by constant boiling at 110° C for 24 h) can be quantified from a maximum absorbance at 454 nm. Aldehyde groups are formed by oxidateive damage to proteins, which can be detected by conjugation to decarboxylated 6-aminofluorescein. 6-Aminofluorescein has been used to determine its ability to potentiate the antiviral activity of poly r (A-U).
References
[1] BHARATE G Y, QIN H, FANG J. Poly(Styrene-Co-Maleic Acid)-Conjugated 6-Aminofluorescein and Rhodamine Micelle as Macromolecular Fluorescent Probes for Micro-Tumors Detection and Imaging[J]. Journal of Personalized Medicine, 2022, 12. DOI:10.3390/jpm12101650.
[2] Müller, Werner EG, and Heinz Christoph Schr?der, eds. Biological Response Modifiers—Interferons, Double-Stranded RNA and 2′, 5′-Oligoadenylates. Vol. 14. Springer Science & Business Media, 2012.
6-Aminofluorescein Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Hongxiong | +undefined18915499068 | China | 120 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12459 | 58 | Inquiry |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +86-86177 | China | 2952 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8828 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Xi'an Yutbon Pharmaceutical Technology Co., Ltd | 029-81140587 +8618717328141 | China | 453 | 58 | Inquiry |