Tranylcypromine Hemisulfate
- CAS No.
- 13492-01-8
- Chemical Name:
- Tranylcypromine Hemisulfate
- Synonyms
- parnate;tranylcyprominesulfate;tranylcyprominesulphate;phenylcycloprominesulfate;TRANYLCYPROMINE HEMISULFATE;TRANYLCYPROMINE HEMISULFATE SALT;Tranylcypromine Sulfate (125 mg);Tranylcypromine Sulfate (1672905);1-amino-2-phenylcyclopropanesulfate;trans,d,l-2-phenylcyclopropylaminesulfate
- CBNumber:
- CB2314310
- Molecular Formula:
- C9H13NO4S
- Molecular Weight:
- 231.27
- MOL File:
- 13492-01-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/7 19:09:42
| storage temp. | 15-25°C |
|---|---|
| solubility | Soluble in water; very slightly soluble in ethanol (96%) and in ether . |
| form | White solid. |
| color | White |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 3 months. |
| InChIKey | BKPRVQDIOGQWTG-FKXFVUDVSA-N |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300-H311+H331 |
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311 |
| Hazard Codes | T |
| Risk Statements | 23/24/25 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | GZ2625000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2921490002 |
Tranylcypromine Hemisulfate price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | PHR3427 | Tranylcypromine Sulfate pharmaceutical secondary standard, certified reference material | 13492-01-8 | 250MG | ₹20643.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P1761 | trans-2-Phenylcyclopropylamine hemisulfate salt | 13492-01-8 | 25G | ₹61345.28 | 2022-06-14 | Buy |
Tranylcypromine Hemisulfate Chemical Properties,Uses,Production
Chemical Properties
A white or almost white, crystalline powder.
Uses
Monoamine oxidase inhibitor; antidepressant.
General Description
Tranylcypromine sulfate, (±)-trans-2-phenylcyclopropylaminesulfate (Parnate), was synthesized to be an amphetamineanalog (visualize the α-methyl of amphetaminecondensed onto the β-carbon atom).It does have someamphetamine-like properties, which may be why it has moreimmediate CNS-stimulant effects than agents that act byMAO inhibition alone. For MAO inhibition, there may betwo components to the action of this agent. One is thoughtto arise because tranylcypromine has structural features (thebasic nitrogen and the quasi-π character of the α- andβ-cyclopropane carbon atoms) that approximate the transitionstate in a route of metabolism of β-arylamines. As α-and β-hydrogen atoms are removed from the normal substrateof the enzyme, the quasi-π character develops over theα,β-carbon system. Duplication of the transition state permitsextremely strong, but reversible, attachment to the enzyme.Additionally, tranylcypromine is a mechanism-based inactivator.It is metabolized by MAO, with one electron of the nitrogenpair lost to flavin. This, in turn, produces homolyticfission of a carbon–carbon bond of cyclopropane, with oneelectron from the fission pairing with the remaining lone nitrogenelectron to generate an imine (protonated) and with theother residing on a methylene carbon. Thus, a free radical isformed that reacts to form a covalent bond with the enzymeor with reduced flavin to inactivate the enzyme.
Tranylcypromine Hemisulfate Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Sekhment pharmaventures | +91-9030088669 +91-9030088669 | Mumbai, India | 105 | 58 | Inquiry |
| Centaur Pharmaceuticals Pvt Ltd | +912266499100 | Mumbai, India | 33 | 58 | Inquiry |
| Nuray Chemicals Pvt Ltd | +91-4066616700 +91-8220444745 | Tamil Nadu, India | 49 | 58 | Inquiry |
| CENTAUR PHARMACEUTICALS PRIVATE LTD | +91 22 – 66499100 | New Delhi, India | 17 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
| Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 | China | 1003 | 58 | Inquiry |
| HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 | China | 931 | 58 | Inquiry |