tranylcypromine

tranylcypromine  Structure
CAS No.
155-09-9
Chemical Name:
tranylcypromine
Synonyms
C07155;SKF-385;Tranyl cipromine;dl-Tranylcypromine;(RS)-TranylcyproMine;(rel)-Tranylcypromine;Tranylcypromine (GMP);Transamine【thymoleptic】;rac-trans-TranylcyproMine;(1R,2S)-rel-2-Phenylcyclopropanamine
CBNumber:
CB8926373
Molecular Formula:
C9H11N
Molecular Weight:
133.19
MOL File:
155-09-9.mol
Modify Date:
2024/3/27 14:23:05

tranylcypromine Properties

Melting point 28 °C
Boiling point bp1.5-1.6 79-80°
Density 1.065±0.06 g/cm3(Predicted)
pka 8.24±0.10(Predicted)
EPA Substance Registry System Cyclopropanamine, 2-phenyl-, (1R,2S)-rel- (155-09-9)

tranylcypromine Chemical Properties,Uses,Production

World Health Organization (WHO)

Tranylcypromine, a monoamine oxidase inhibitor (MAOI), was introduced in 1961 for the treatment of depressive illness. By 1964 its use had been associated with transient hypertensive crises and other adverse effects when taken together with certain cheeses and other foods containing tyramine. This led to the withdrawal of the drug in several countries and the suspension of marketing on a worldwide basis by the major manufacturer pending review of these adverse reactions. Subsequently, in response to requests from the medical profession, tranylcypromine was resubmitted for registration with appropriate warnings in the product information and it is now marketed in more than 30 countries.

tranylcypromine Preparation Products And Raw materials

Raw materials

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Preparation Products

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tranylcypromine Spectrum

Tranyl cipromine (1R,2S)-rel-2-Phenylcyclopropanamine Cyclopropanamine, 2-phenyl-, (1R,2S)-rel- Tranylcypromine (base and/or unspecified salts) dl-Tranylcypromine SKF-385 Transamine【thymoleptic】 C07155 (RS)-TranylcyproMine rac-trans-TranylcyproMine (1R,2S)‐rel-2‐phenylcyclopropan‐1‐amine (rel)-Tranylcypromine Ticagrelor Impurity 240 (Tranylcypromine) Tranylcypromine (GMP) (1R,2S)-2-phenylcyclopropane-1-amine 155-09-9