ChemicalBook > Product Catalog >API >Hormones and the Endocrine System >Pancreatic hormone and blood sugar regulation >Mitiglinide calcium dihydrate
Mitiglinide calcium dihydrate
- CAS No.
- 207844-01-7
- Chemical Name:
- Mitiglinide calcium dihydrate
- Synonyms
- Mitiglinide calcium;KAD-1229 Calcium Hydrate;Mitig;MitigL;inide caL;KAD-1229 calcium salt;Miglinide Calcium API;S-21403 calcium hydrate;Mitiglinide CalciuM dihydrate;3006 MITIGLINIDE CALCIUM HYDRATE
- CBNumber:
- CB2336628
- Molecular Formula:
- C38H52CaN2O8
- Molecular Weight:
- 704.91
- MOL File:
- 207844-01-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/9/14 16:39:35
| Melting point | 179-185°C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Methanol (Slightly) |
| form | Solid |
| color | White |
| InChIKey | QEVLNUAVAONTEW-HNIWBTCONA-L |
| SMILES | N1(C[C@]2([H])CCCC[C@]2([H])C1)C(=O)C[C@H](CC1=CC=CC=C1)C(=O)O[Ca]OC(=O)[C@@H](CC1=CC=CC=C1)CC(=O)N1C[C@@]2([H])CCCC[C@@]2([H])C1.O.O |&1:2,8,14,29,42,48,r| |
| CAS DataBase Reference | 207844-01-7(CAS DataBase Reference) |
Mitiglinide calcium dihydrate Chemical Properties,Uses,Production
Description
Mitiglinide calcium hydrate (KAD-1229) is an insulinotropic agent. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Chemical Properties
White Solid
Uses
KAD-1229 Calcium Hydrate (Mitiglinide calcium dihydrate) could binds to sulfonylurea receptors and inhibits the activity of ATP-sensitive K+ channel in MIN 6 cells. Antidiabetic.
Mechanism of action
Mitiglinide is thought to stimulate insulin secretion by closing the ATP-sensitive K(+) (K(ATP)) channels in pancreatic beta-cells, and its early insulin release and short duration of action would be effective in improving postprandial hyperglycemia.
Mitiglinide calcium dihydrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 250)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| SHANDONG BOYUAN PHARMACEUTICAL CO., LTD. | +86-0531-69954981 +8615666777973 | China | 211 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21663 | 55 | Inquiry |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | China | 1807 | 55 | Inquiry |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9262 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29899 | 58 | Inquiry |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | China | 8819 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| Jinan Honest Pharm Co., Ltd | +8615318812076 | China | 286 | 58 | Inquiry |
207844-01-7(Mitiglinide calcium dihydrate)Related Search:
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