Nitrendipine
- CAS No.
- 39562-70-4
- Chemical Name:
- Nitrendipine
- Synonyms
- Nitrendipin;3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;Deiten;nidrel;Nitrepin;baye5009;baypress;bayotensin;Bylotensin;NITRENDIPINE
- CBNumber:
- CB2395104
- Molecular Formula:
- C18H20N2O6
- Molecular Weight:
- 360.36
- MOL File:
- 39562-70-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/6 14:33:24
| Melting point | 1580C |
|---|---|
| Boiling point | 492.4°C (rough estimate) |
| Density | 1.3595 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | 2-8°C |
| solubility | methanol: 15 mg/mL |
| form | powder |
| pka | 2.79±0.70(Predicted) |
| color | yellow to green |
| Water Solubility | Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water. |
| Stability | Stable for 1 year from date of purchase as supplied. Protect from light. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 week. |
| CAS DataBase Reference | 39562-70-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Nitrendipine(39562-70-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H312-H332 | |||||||||
| Precautionary statements | P261-P280h-P301+P312a-P304+P340-P321-P501a | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | US5653000 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 39, 12.6 i.v.; 2540, >10000 orally (Hoffmann) | |||||||||
| NFPA 704 |
|
Nitrendipine price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | N144 | Nitrendipine >95%, powder | 39562-70-4 | 25MG | ₹7945.55 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N144 | Nitrendipine >95%, powder | 39562-70-4 | 100MG | ₹28913.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | N144 | Nitrendipine >95%, powder | 39562-70-4 | 500MG | ₹93885.23 | 2022-06-14 | Buy |
Nitrendipine Chemical Properties,Uses,Production
Description
Nitrendipine is a vasodilating, dihydropyridine calcium antagonist. Its prolonged therapeutic effect in comparison to nifedipine makes it useful in the once to twice daily treatment of hypertension.
Chemical Properties
Crystalline Solid
Uses
Nitrendipine is a dihydropyridine calcium channel blocker. Nitrendipine is used in the treatment of primary (essential) hypertension to decrease blood pressure. Antihypertensive.
Definition
ChEBI: A dihydropyridine that is 1,4-dihydropyridine substituted by methyl groups at positions 2 and 6, a 3-nitrophenyl group at position 4, a ethoxycarbonyl group at position 3 and a methoxycarbonyl group at position 5. It is a calcium-channel blocker used in t e treatment of hypertension.
General Description
Nitrendipine, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ethylester (Baypress), is a second-generation dihydropyridinechannel blocker of the nifedipine type. It is more selectivefor vascular smooth muscle than for myocardial tissue andserves as an effective vasodilator. The drug is used in thetreatment of mild-to-moderate essential hypertension.
Biological Activity
L-type calcium channel blocker.
Nitrendipine Preparation Products And Raw materials
Global( 428)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Vivimed Labs Ltd | +914066086608 | Telangana, India | 61 | 58 | Inquiry |
| Concept Pharmaceuticals Ltd | +91-2242418888 +91-2242418888 | Maharashtra, India | 19 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 | China | 2141 | 58 | Inquiry |
39562-70-4(Nitrendipine)Related Search:
NITRENDIPINE
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylicacidethy
baye5009
bayotensin
baypress
ethylmethyl1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxy
2，6-Dimethyl-4-(3-nitrophenyl)-1，4-dihydro-3，5-pyridinedicarboxylic acid methyl ethyl ester
Bylotensin
Deiten
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester (9CI)
Nitrepin
Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 5-ethyl 3-methyl ester
4-(3-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl 5-methyl ester
3-ethyl 5-Methyl (4R)-2,6-diMethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Lercanidipine Ethyl Methyl Ester IMpurity (IMpurity 5)
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
Nitrendipine for peak identification
(RS)-Methylethyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
lmethylester
nidrel
ylmethylester
ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate
1,4-DIHYDRO-2,6-DIMETHYL-4-(3'-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID ETHYL METHYL ESTER
1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)-3,5-PYRIDINEDICARBOXYLIC ACID ETHYL METHYL ESTER
NITRENDIPINE >95% CA2+ CHANNEL BLOCKER,
NITRENDIPINE EPN(CRM STANDARD)
(NITROPHENYLPYRIDINE ANALOGUE) EPN(CRM STANDARD)
NITRENDIPINE IMPURITY AETHYL METHYL-2,6-DIMETHYL-4-(3-NITROPHENYL) PYRIDINE-3,5-DICARBOXYLATE
NITRENDIPINE MM(CRM STANDARD)
Nitrendipine, ≥95.0%
Group horizon
Nitrendipine for system suitability CRS
Nitrendipine CRS
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-ethyl 5-methyl ester
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate Ethyl Methyl Ester
Ethyl Methyl 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
Nitrendipine USP/EP/BP
Nitrendipiner
Nitrendipine, Pharma
Lercanidipine methyl ethyl ester imp
Nitrendipine (BAY-E-5009)
Nitrendipine Impurity1218
Lercanidipine Ethyl Methyl Ester Impurity
Nitrendipine D5Q: What is
Nitrendipine D5 Q: What is the CAS Number of
Nitrendipine D5 Q: What is the storage condition of
Nitrendipine D5
NitrendipineQ: What is
Nitrendipine Q: What is the CAS Number of
Nitrendipine Q: What is the storage condition of
Nitrendipine Q: What are the applications of
Nitrendipine
Nitrendipin
3-ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Group of horizon
39562-70-4
C18H20N2O6
36036
Calcium Channel Modulators
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Ion Channels
Inhibitors and Activators