MIBEFRADIL DIHYDROCHLORIDE

CAS No.: 116644-53-2

Chemical Name:: MIBEFRADIL DIHYDROCHLORIDE

Synonyms: C07222;RO 40-5967;MIBEFRADIL DIHYDROCHLORIDE;(1S,2S)-2-[2-[[3-(2-Benzimidazolyl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate;[(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate;(1S,2S)-2-[2[[3-(2-BENZIMIDAZOLYLPROPYL]METHYLAMINO]ETHYL]-6-FLUORO-1,2,3,4-TETRAHYDRO-1-ISOPROPYL-2-NAPHTHYL METHOXYACETATE DIHYDROCHLORIDE;Methoxyacetic acid [[(1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropylnaphthalen]-2-yl] ester;Acetic acid, methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester;Acetic acid, Methoxy-, 2-[2-[[3-(1H-benziMidazol-2-yl)propyl]MethylaMino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-Methylethyl)-2-naphthalenylester, (1S-cis)-;(1S,2S)-2-[2-[[3-(1H-Benzimidazol-2yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenylmethoxyacetoacetatedihydrochloride

CBNumber:: CB2399511

Molecular Formula:: C29H38FN3O3

Molecular Weight:: 495.63

MOL File:: 116644-53-2.mol

Modify Date:: 2023/5/18 11:31:06

Request For Quotation

MIBEFRADIL DIHYDROCHLORIDE Properties

Melting point	125 - 130°C
Boiling point	647.6±55.0 °C(Predicted)
Density	1.18±0.1 g/cm3(Predicted)
storage temp.	Desiccate at RT
solubility	DMSO (Slightly), Methanol (Slightly)
pka	11.93±0.10(Predicted)
form	Solid
color	Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

MIBEFRADIL DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

Vasodilator.

Biological Activity

Ca 2+ channel blocker with moderate selectivity for T-type Ca 2+ channels displaying IC 50 values of 2.7 μ M and 18.6 μ M for T-type and L-type channels respectively. Antihypertensive agent.

MIBEFRADIL DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

(S)-6-FLUORO-1-ISOPROPYL-3,4-DIHYDRO-1H-NAPHTHALEN-2-ONE Methoxyacetyl chloride Sodium bis(2-methoxyethoxy)aluminiumhydride

Preparation Products

MIBEFRADIL DIHYDROCHLORIDE Suppliers

Global( 52)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharma Affiliates	172-5066494	Haryana, India	6761	58	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9322	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
LEAP CHEM CO., LTD.	+86-852-30606658	China	24738	58	Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	China	8474	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Raw material medicin reagent co.,Ltd		China	4533	58	Inquiry
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810	China	3750	55	Inquiry
Chengdu Dianchun Technology Co., Ltd	400-1166-196 18502815961	China	14623	60	Inquiry

Supplier	Advantage
Pharma Affiliates	58
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Baoji Guokang Bio-Technology Co., Ltd.	58
InvivoChem	58
LEAP CHEM CO., LTD.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Amadis Chemical Company Limited	58
Raw material medicin reagent co.,Ltd	58
Nanjing Sunlida Biological Technology Co., Ltd.	55
Chengdu Dianchun Technology Co., Ltd	60

MIBEFRADIL DIHYDROCHLORIDE Spectrum

MIBEFRADIL DIHYDROCHLORIDE(116644-53-2)MS

116644-53-2(MIBEFRADIL DIHYDROCHLORIDE)Related Search:

CLONIDINE Mecamylamine hydrochloride Methyldopa Loperamide Carbenoxolone disodium

Miglitol Amlodipine Lercanidipine Itraconazole Diltiazem

MIBEFRADIL DIMETHYL PHENYL ETHYL CARBINYL ACETATE BETA PHENYL ETHYL METHYL ETHYL CARBINYL ACETATE Dimethylbenzylcarbinyl acetate 6-FLUORO-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-OL

MIBEFRADIL DIHYDROCHLORIDE 3-(1H-IMIDAZOL-2-YL)PROPAN-1-AMINE 1-(4-FLUORO-PHENYL)-2-METHYL-PROPAN-2-OL

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C07222 (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenylmethoxyacetoacetatedihydrochloride Acetic acid, Methoxy-, 2-[2-[[3-(1H-benziMidazol-2-yl)propyl]MethylaMino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-Methylethyl)-2-naphthalenylester, (1S-cis)- (1S,2S)-2-[2-[[3-(2-Benzimidazolyl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate (1S,2S)-2-[2-[[3-(1H-BENZIMIDAZOL-2YL)PROPYL]METHYLAMINO]ETHYL]-6-FLUORO-1,2,3,4-TETRAHYDRO-1-(1-METHYLETHYL)-2-NAPHTHALENYL METHOXYACETOACETATE DIHYDROCHLORIDE (1S,2S)-2-[2[[3-(2-BENZIMIDAZOLYLPROPYL]METHYLAMINO]ETHYL]-6-FLUORO-1,2,3,4-TETRAHYDRO-1-ISOPROPYL-2-NAPHTHYL METHOXYACETATE DIHYDROCHLORIDE RO 40-5967 MIBEFRADIL DIHYDROCHLORIDE Methoxyacetic acid [[(1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropylnaphthalen]-2-yl] ester [(1S,2S)-2-[2-[3-(1H-benzimidazol-2-yl)propyl-methylamino]ethyl]-6-fluoro-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl] 2-methoxyacetate Acetic acid, methoxy-, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester 116644-53-2 C29H38FN3O3