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3-CYANO-7-ETHOXYCOUMARIN

3-CYANO-7-ETHOXYCOUMARIN Structure
CAS No.
117620-77-6
Chemical Name:
3-CYANO-7-ETHOXYCOUMARIN
Synonyms
3-CETC;3-CYANO-7-ETHOXYCOUMARIN;CEC [3-Cyano-7-ethoxycoumarin;7-ETHOXYCOUMARIN-3-CARBONITRILE;7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile;3-CYANO-7-ETHOXYCOUMARIN ISO 9001:2015 REACH;7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile;2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo-;CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6*;2H-1-Benzopyran-3-carbonitrile,7-ethoxy-2-oxo-(9CI)
CBNumber:
CB2732282
Molecular Formula:
C12H9NO3
Molecular Weight:
215.2
MOL File:
117620-77-6.mol
MSDS File:
SDS
Modify Date:
2023/7/12 17:07:10

3-CYANO-7-ETHOXYCOUMARIN Properties

Melting point 210-212°C
Boiling point 396.8±42.0 °C(Predicted)
Density 1.29±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: soluble
form Solid
color yellow to orange
λmax 356 nm (Buffer pH7); 355 nm(MeOH)
Biological Applications As a substrate for measuring cytochrome P450 enzymes activity; cytochrome P450 inhibition assays; drug design; drug metabolism; treating viral or parasite infections.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38
Safety Statements  26-36
WGK Germany  3
NFPA 704
0
3 0

3-CYANO-7-ETHOXYCOUMARIN price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) UC455 3-Cyano-7-ethoxycoumarin ≥97% (HPLC) 117620-77-6 5MG ₹26695.5 2022-06-14 Buy
Sigma-Aldrich(India) UC455 3-Cyano-7-ethoxycoumarin ≥97% (HPLC) 117620-77-6 10MG ₹48040.8 2022-06-14 Buy
Product number Packaging Price Buy
UC455 5MG ₹26695.5 Buy
UC455 10MG ₹48040.8 Buy

3-CYANO-7-ETHOXYCOUMARIN Chemical Properties,Uses,Production

Uses

3-Cyano-7-ethoxycoumarin has been used as a substrate in cytochrome P (CYP) inhibition for fluorescence measurement.

General Description

3-Cyano-7-ethoxycoumarin is a fluorescent substrate for Cytochrome P450 1A1 (CYP1A1), Cytochrome P450 1A2 (CYP1A2), Cytochrome P450 2C9 (CYP2C9) and Cytochrome P450 2C19 (CYP2C19).

Biochem/physiol Actions

Fluorescent probe useful in microsomal dealkylase studies. Typical drug-drug interactions resulting from enzyme inhibition.

3-CYANO-7-ETHOXYCOUMARIN Preparation Products And Raw materials

Raw materials

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Preparation Products

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7-Ethoxy-2-oxo-2H-chroMene-3-carbonitrile 7-ETHOXYCOUMARIN-3-CARBONITRILE 3-CYANO-7-ETHOXYCOUMARIN 2H-1-Benzopyran-3-carbonitrile,7-ethoxy-2-oxo-(9CI) 3-Cyano-7-ethoxycoumarin [7-Ethoxycoumarin-3-carbonitrile] *Cytochrome P450 Substrate* 7-Ethoxy-2-oxo-2H-1-benzopyran-3-carbonitrile CEC [3-Cyano-7-ethoxycoumarin] *CAS 117620-77-6* CEC [3-Cyano-7-ethoxycoumarin 2H-1-Benzopyran-3-carbonitrile, 7-ethoxy-2-oxo- 3-CYANO-7-ETHOXYCOUMARIN ISO 9001:2015 REACH 3-CETC 117620-77-6 11620-77-6 BioChemical Biochemicals and Reagents Luminescent Compounds/Detection Other luminescent compounds ETHOXY Coumarins Detection and Quantitation Reagents Multi-Drug Resistance and Drug Metabolism Drug and Xenobiotic Metabolism Substrates, Inducers, Inhibitors