norfenefrine

CAS No.: 536-21-0

Chemical Name:: norfenefrine

Synonyms: Normetol;Normezaton;Metacardiol;Brn 1211018;norfenefrine;m-Octopamine;Metaoctopamine;DL-m-Octopamine;NORFENEFRINEBASE;Normetasympathol

CBNumber:: CB2902175

Molecular Formula:: C8H11NO2

Molecular Weight:: 153.18

MOL File:: 536-21-0.mol

MSDS File:: SDS

Modify Date:: 2023/5/4 17:34:39

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norfenefrine Properties

Melting point	75-77 °C
Boiling point	276.1°C (rough estimate)
Density	1.1577 (rough estimate)
refractive index	1.5010 (estimate)
pka	pKa 8.67(H2O,t undefined,I undefined) (Uncertain)

SAFETY

Risk and Safety Statements

Toxicity	LD50 oral in rat: 390mg/kg

norfenefrine Chemical Properties,Uses,Production

Originator

Zordel,Grelan,Japan,1970

Manufacturing Process

100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.

Therapeutic Function

Adrenergic

norfenefrine Preparation Products And Raw materials

Raw materials

Hexamethylenetetramine Hydrogen Sodium iodide 3'-Acetoxyacetophenone Benzenemethanol, 3-hydroxy-α-(nitromethyl)-

1-(2-aMino-3-hydroxyphenyl)ethanone Phenol, 3-(8-nonen-1-yl)- APLPHA-BROMO-M-BENZOYLOXYACETOPHENONE m-vinylphenol 2-Bromo-3′-hydroxyacetophenone

3-HYDROXYM AND ELONITRILE 3-Hydroxybenzaldehyde

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Preparation Products

norfenefrine Suppliers

Global( 11)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-29-87569266 15319487004	China	2016	58	Inquiry
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	China	34571	58	Inquiry
Lanospharma Laboratories Co.,Ltd	13440048448	China	6343	56	Inquiry
Leancare Ltd.	+33 962096793	United Kingdom	6460	42	Inquiry
Bejing Famous Pharmaceutical Technology Co., Ltd.	13331045123	China	14232	58	Inquiry
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	China	18018	56	Inquiry
Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd	02783850058 15377551550	China	2429	58	Inquiry
Shandong Wadesen Biotechnology Co. LTD	0531-88723173 18596073690	China	3856	58	Inquiry

Supplier	Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd	58
Shaanxi Dideu Medichem Co. Ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Lanospharma Laboratories Co.,Ltd	56
Leancare Ltd.	42
Bejing Famous Pharmaceutical Technology Co., Ltd.	58
ChemStrong Scientific Co.,Ltd	56
Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd	58
Shandong Wadesen Biotechnology Co. LTD	58

536-21-0(norfenefrine)Related Search:

DL-ADRENALINE HYDROCHLORIDE Levisoprenaline Norfenefrine hydrochloride DL-NORADRENALINE HYDROCHLORIDE (+)-Bicuculline

Phenylephrine hydrochloride Isoprenaline hydrochloride L-NORADRENALINE BITARTRATE L-ADRENALINE BITARTRATE (-)-BICUCULLINE METHOBROMIDE

Isoprenaline sulphate (2RS,3RS)-2-AMINO-3-(3,4-DIHYDROXY-PHENYL)-3-HYDROXY-PROPIONIC ACID Norepinephrine DL-Adrenalin Phenylephrine

(S)-(+)-ISOPROTERENOL L(+)-BITARTRATE Octopamine DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE

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norfenefrine NORFENEFRINEBASE (+-)-m-Octopamine (+-)-Norphenylephrine 1-(3-Hydroxyphenyl)-2-aminoethanol 1-(m-Hydroxyphenyl)-2-aminoethanol a-(Aminomethyl)-m-hydroxybenzyl alcohol Benzenemethanol, a-(aminomethyl)-3-hydroxy- (9CI) Benzyl alcohol, a-(aminomethyl)-m-hydroxy- (6CI, 8CI) DL-1-(3-Hydroxyphenyl)-2-aminoethanol dl-1-(m-Hydroxyphenyl)-2-aminoethanol DL-m-Octopamine DL-Norphenylephrine Metacardiol Metaoctopamine m-Hydroxyphenylethanolamine m-Octopamine Normetasympathol Normetasynephrine Normetol Normezaton p-Hydroxynoradrenaline rac-(R*)-2-Amino-1-(3-hydroxyphenyl)ethanol 1-(3-Hydroxyphenyl)-1-hydroxy-2-aminoethane 4779-94-6 (Hydrochloride) alpha-(Aminomethyl)-m-hydroxybenzyl alcohol Benzyl alcohol, alpha-(aminomethyl)-m-hydroxy- Brn 1211018 Einecs 208-626-8 alpha-(AMinoMethyl)-3-hydroxybenzeneMethanol Benzenemethanol, α-(aminomethyl)-3-hydroxy- Norfenefrine Impurity A Etilefrine hydrochloride EP Impurity C 536-21-0