(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol

CAS No.: 142217-78-5

Chemical Name:: (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol

Synonyms: Entecavir-5;Entecavir E5;N-oxide impurity1;Entecavir Impurity 1;Entecavir Impurity 53;Entecavir Impurity 13;Entecavir InterMediate V;Entecavir intermediate N5;ENTECAVIR INTERMEDIATE (5TH);Entecavir InterMediate (CAS # 142217-78-5)

CBNumber:: CB31450658

Molecular Formula:: C52H49N5O5

Molecular Weight:: 823.98

MOL File:: 142217-78-5.mol

MSDS File:: SDS

Modify Date:: 2024/7/15 16:45:23

Request For Quotation

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Properties

Melting point	>87°C (dec.)
Density	1.23
storage temp.	2-8°C
solubility	Acetonitrile (Slightly, Sonicated), DMSO (Slightly, Sonicated), Methanol (Slightly, Sonicated)
pka	13.87±0.70(Predicted)
form	Solid
color	White to Off-White
Stability	Hygroscopic
CAS DataBase Reference	142217-78-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Chemical Properties,Uses,Production

Uses

Entecavir-?5 is used in the preparation of the anti-?HBV drug Entecavir.

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Preparation Products And Raw materials

Raw materials

Preparation Products

2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine

(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol Suppliers

Global( 188)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Parth Antibiotics Pvt Ltd.	+91 (22) 2562-8329	New Delhi, India	173	50	Inquiry
Manus Aktteva	+91 (79) 6512-3395	New Delhi, India	581	34	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
SynZeal Research Pvt Ltd	+1 226-802-2078	Gujarat, India	6522	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	China	10991	58	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	18623	58	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21663	55	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9261	55	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry

Supplier	Advantage
Parth Antibiotics Pvt Ltd.	50
Manus Aktteva	34
Pharmaffiliates Analytics and Synthetics P. Ltd	58
SynZeal Research Pvt Ltd	58
CLEARSYNTH LABS LTD.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60

142217-78-5((2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol)Related Search:

4-Methoxybenzyl cyanide (Trifluoromethoxy)benzene Glycine 6-Aminocaproic acid 4-Methoxyphenol

p-Anisidine ALTRENOGEST p-Anisaldehyde Tris(hydroxymethyl)aminomethane 4-Methoxybenzyl alcohol

4-Methoxybenzoic acid Guaiacol Anisole 6-(Benzyloxy)-9-((1S,3S)-4-(benzyloxy)-3-((benzyloxy)methyl)-2-methylenecyclopentyl)-N-((4-methoxyphenyl)diphenylmethyl)-9H-purin-2-amine (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol

(1s-trans)-2-[(phenylmethoxy)methyl]-3-cyclopenten-1-ol 2-AMino-1,9-dihydro-9-[(1S,3R,4S)-4-(hydroxydiMethylsilyl)-3-(hydroxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one Entecavir

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(2R,3S,5S)-3-(Benzyloxy)-5-(6-benzyloxy)-2-(4-methyoxyphenyl)diphenylmethylamino)-9H-purin-9-yl)-2-benzyloxymethyl)cyclopentanol (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9- (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol ,99% [1S-(1α,2β,3α,5β)]-5-[2-[[(4-Methoxyphenyl)-diphenylMethyl]aMino]-6-(phenylMethoxy)-9H- purin-9-yl]-3-(phenylMethoxy)-2-[(phenyl-Methoxy)Methyl]cyclopentanol Entecavir InterMediate V (1S,2S,3S,5S)-5-(2-((4-Methoxyphenyl)diphenylMethylaMino)-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((benzyloxy)Methyl)cyclopentanol Entecavir-5 (1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-Methoxyphenyl)diphenylMethyl)aMino)-9H-purin-9-yl)-2-((benzyloxy)Methyl)cyclopentanol Entecavir Impurity 53 (1S,2S,3S,5S)-3-(benzyloxy)-5-[6-(benzyloxy)-2-{[(4-methoxyphenyl)diphenylmethyl]amino}-9H-purin-9-yl]-2-[(benzyloxy)methyl]cyclopentan-1-ol 5-[2-[[(4-methoxyphenyl)-diphenylmethyl]amino]-6-phenylmethoxy-9-purinyl]-3-phenylmethoxy-2-(phenylmethoxymethyl)-1-cyclopentanol The China supplier of Entecavir Intermediate Cas:142217-78-5 (1S,3R,4S)-3-(benzyloxy-5-[6-(benzyloxy)-2 -((4-Methoxyphenyl)diphenylMethylaMino) -9H- purin-9-yl]-2-(benzyloxyMethyl)cyclopentanol Entecavir InterMediate (CAS # 142217-78-5) (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-Methoxyphenyl)diphenylMethyl]aMino]-6-(phenylMethoxy)-9H-purin-9-yl]-2-(benzyloxyMethyl)cyclopentanol (interMediate step 4) (1S,2S,3S,5S)-3-BENZYLOXY)-5(6-BENZYLOXY)-2-((4-METHOXYPHENYL)DIPHENYLMETHYLAMINO)-9H-PURIN-9-YL)-2-(BENZYLOXYMETH (2R,3S,5S)-3-(Benzyloxy)-5-[6-(benzyloxy)-2-{[(4-Methoxyphenyl)(diphenyl)Methyl]aMino}-9H-purin-9-yl]-2-[(benzyloxy)Methyl]cyclopentanol (2R,3S,5S)-3-(benzyloxy)-5-[6-(benzyloxy)-2-{[(4-Methoxyphenyl)diphenylMethyl]aMino}-9H-purin-9-yl]-2-[(benzyloxy)Methyl]cyclopentan-1-ol (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethyl amino)-9H-purin- (1S,2S,3S,5S)-5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol Entecavir E5 (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol###142217-78-5 (1S,2S,3S,5S)-3-(Benzyloxy)-5-(6-(benzyloxy)-2-(((4-methoxyphenyl)diphenylmethylamino)-9H-puri (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-pu Entecavir intermediate N5 Entecavir Impurity 13 ENTECAVIR INTERMEDIATE (5TH) 2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-a(benzyloxymethyl)cyclopentanol Entecavir Impurity 1 N-oxide impurity1 Cyclopentanol, 5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S)- 5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmet... "(2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)" (1S,2S,3S,5S)-5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phen (2R,3S,5S)-3- (Benzyloxy)-5-[2-[[(4-methoxyphenyl)- diphenylmethyl]amino]-6- (phenylmethoxy)-9H-purin-9-yl]- 2- (benzyloxymethyl) cyclopentanol (Ent-V) (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylm 142217-78-5 42217-78-5 C52H49N5O5