2-Thiopheneacetyl chloride
- CAS No.
- 39098-97-0
- Chemical Name:
- 2-Thiopheneacetyl chloride
- Synonyms
- SKL1309;AKOS BBS-00003919;2-ThiopheneacetyL;TIMTEC-BB SBB006705;2-Thiopheneacetyl ch;Articaine Impurity 2;Articaine Impurity 11;2-THIENYLACETYL CHLORIDE;Articaine Impurities1823;Thien-2-ylacetyl chloride
- CBNumber:
- CB3152140
- Molecular Formula:
- C6H5ClOS
- Molecular Weight:
- 160.62
- MOL File:
- 39098-97-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/1/25 9:38:39
Boiling point | 105-106 °C/22 mmHg (lit.) 130-135 °C/90 mmHg (lit.) |
---|---|
Density | 1.303 g/mL at 25 °C (lit.) |
vapor pressure | 4 mm Hg ( 83 °C) |
refractive index |
n |
Flash point | 215 °F |
storage temp. | 2-8°C |
form | Liquid |
color | Clear brown |
Specific Gravity | 1.303 |
Water Solubility | Reacts with water. |
Sensitive | Moisture Sensitive |
BRN | 114547 |
InChIKey | AJYXPNIENRLELY-UHFFFAOYSA-N |
CAS DataBase Reference | 39098-97-0(CAS DataBase Reference) |
EPA Substance Registry System | 2-Thiopheneacetyl chloride (39098-97-0) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
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Signal word | Danger | |||||||||
Hazard statements | H314 | |||||||||
Precautionary statements | P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | |||||||||
Hazard Codes | C | |||||||||
Risk Statements | 14-34-37-29 | |||||||||
Safety Statements | 26-28-36/37/39-45-8-30-23 | |||||||||
RIDADR | UN 3265 8/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 8-10-21 | |||||||||
TSCA | T | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
2-Thiopheneacetyl chloride price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 195995 | 2-Thiopheneacetyl chloride 98% | 39098-97-0 | 25G | ₹5802.2 | 2022-06-14 | Buy |
TCI Chemicals (India) | T1751 | Thiophene-2-acetyl Chloride min. 98.0 % | 39098-97-0 | 25G | ₹5300 | 2022-05-26 | Buy |
TCI Chemicals (India) | T1751 | Thiophene-2-acetyl Chloride min. 98.0 % | 39098-97-0 | 250G | ₹29000 | 2022-05-26 | Buy |
2-Thiopheneacetyl chloride Chemical Properties,Uses,Production
Description
2-Thiopheneacetyl chloride is used as a reagent to synthesize diamide derivatives of (S)-BINOL. These derivatives display potential anti-inflammatory and anti-arthritis effects. 2-Thiopheneacetyl chloride is also used in the synthesis of Nitrocefin (N493815), a chromogenic substrate that changes colour in the presence of β-lactamases and penicillin-binding proteins.
Chemical Properties
CLEAR BROWN LIQUID
Uses
2-Thiopheneacetyl chloride was used in the synthesis of (S)-ethyl-1-(2-thiopheneacetyl)-3-piperidinecarboxylate, nipecotate-containing immunopotentiator, 5-fluorouracil-cephalosporin prodrug, series of new N,N?-di(thiopheneacetyl)diamines derivatives and 6-β-(thiophen-2?-yl)acetamidomorphine. Also used in the synthesis of Nitrocefin.
General Description
A clear yellow to dark brown liquid. Insoluble in water and denser than water. Corrosive to skin, and eyes. Vapors severely irritate respiratory tract.
Air & Water Reactions
Insoluble in water. Decomposes exothermically in water yielding fumes of toxic hydrogen chloride.
Reactivity Profile
THIOPHENE-2-ACETYL CHLORIDE is incompatible with water, bases (including amines), with strong oxidizing agents, and with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
2-Thiopheneacetyl chloride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
SGMR PHARMACEUTICALS PVT LTD | +91-9032001889 +91-9032001889 | Telangana, India | 83 | 58 | Inquiry |
Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
Arch Pharmalabs Limited | 09867010022 | Mumbai, India | 63 | 58 | Inquiry |
G.c.intl | 08048372245Ext 789 | Mumbai, India | 105 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
S.R.LABORATORIES | +914027177083 | New Delhi, India | 149 | 30 | Inquiry |
Supplier | Advantage |
---|---|
BTC pharm India | 58 |
SGMR PHARMACEUTICALS PVT LTD | 58 |
Sri Neelima Laboratories | 58 |
Arch Pharmalabs Limited | 58 |
G.c.intl | 58 |
CLEARSYNTH LABS LTD. | 58 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
S.R.LABORATORIES | 30 |
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