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Colestipol hydrochloride

Colestipol hydrochloride Structure
CAS No.
37296-80-3
Chemical Name:
Colestipol hydrochloride
Synonyms
lestid;colestid;cholestabyl;COLESTIPOL HCL;COLESTIPOL HYDROCHLORIDE;Colestipol Hydrochloride (200 mg);Colestipol Hydrochloride (1146505);n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride;N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE
CBNumber:
CB3182169
Molecular Formula:
C8H24ClN5
Molecular Weight:
225.76266
MOL File:
37296-80-3.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

Colestipol hydrochloride Properties

storage temp. Room Temperature, under inert atmosphere
form Solid
color Off-White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
WGK Germany  3
HS Code  3914006000
Toxicity LD50 in rats (mg/kg): >4000 i.p.; >1000 orally (Webster, Bollert)

Colestipol hydrochloride Chemical Properties,Uses,Production

Uses

Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726).

Definition

ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.

General Description

Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias.

Colestipol hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Colestipol Hydrochloride (200 mg) COLESTIPOL HCL COLESTIPOL HYDROCHLORIDE N-(2-AMINOETHYL)-N'-[2-[(2-AMINOETHYL)AMINO]ETHYL]-1,2-ETHANEDIAMINE POLYMER WITH (CHLOROMETHYL)OXIRANE HYDROCHLORIDE n'-(2-aminoethyl)-n-[2-(2-aminoethylamino)ethyl]ethane-1,2-diamine 2-(chloromethyl)oxirane hydrochloride cholestabyl colestid lestid Colestipol Hydrochloride (1146505) 37296-80-3 3729-80-3 C11H28ClN5OHCl