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Liothyronine sodium

Liothyronine sodium Structure
CAS No.
55-06-1
Chemical Name:
Liothyronine sodium
Synonyms
Triostat;Liothyronin sodiuM;Ibiot;Cyomel;T3, NA;Cytobin;Cynomel;Cytomine;Sodium T3;Tertroxin
CBNumber:
CB3195390
Molecular Formula:
C15H11I3NNaO4
Molecular Weight:
672.96
MOL File:
55-06-1.mol
Modify Date:
2024/8/17 21:30:02

Liothyronine sodium Properties

Melting point 205 °C (dec.)(lit.)
alpha 20 º (c=2,alcohol/1.2N HCl)
RTECS YP2836500
storage temp. -20°C
solubility 4 M NH4OH in methanol: 125 g/5mL, clear, yellow-brown
form powder
color White to Pale Brown
Water Solubility Partly miscible in water. Soluble in dimethyl sulfoxide, methanol, sodium hydroxide and ethanol. Practically insoluble in most other organic solvents.
Sensitive Light Sensitive
Merck 5510
BRN 8179867
InChI InChI=1/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/s3
InChIKey SBXXSUDPJJJJLC-ZLBVLXFENA-M
SMILES C1(C(I)=CC(C[C@H](N)C([O-])=O)=CC=1I)OC1=CC=C(O)C(I)=C1.[Na+] |&1:6,r|
CAS DataBase Reference 55-06-1(CAS DataBase Reference)
EPA Substance Registry System L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, monosodium salt (55-06-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05
Signal word  Danger
Hazard statements  H314-H290
Precautionary statements  P501-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405
Hazard Codes  Xn
Risk Statements  20/21/22
Safety Statements  22-24/25-36
WGK Germany  3
3-8-10
HS Code  29379000
NFPA 704
1
0 1

Liothyronine sodium price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T6397 3,3′,5-Triiodo-L-thyronine sodium salt powder, BioReagent, suitable for cell culture 55-06-1 100MG ₹7653.28 2022-06-14 Buy
Sigma-Aldrich(India) T6397 3,3′,5-Triiodo-L-thyronine sodium salt powder, BioReagent, suitable for cell culture 55-06-1 250MG ₹15436.45 2022-06-14 Buy
Sigma-Aldrich(India) T6397 3,3′,5-Triiodo-L-thyronine sodium salt powder, BioReagent, suitable for cell culture 55-06-1 1G ₹38699.38 2022-06-14 Buy
Sigma-Aldrich(India) T5516 3,3′,5-Triiodo-L-thyronine sodium salt γ-irradiated, powder, suitable for, suitable for cell culture 55-06-1 1MG ₹9266.2 2022-06-14 Buy
Product number Packaging Price Buy
T6397 100MG ₹7653.28 Buy
T6397 250MG ₹15436.45 Buy
T6397 1G ₹38699.38 Buy
T5516 1MG ₹9266.2 Buy

Liothyronine sodium Chemical Properties,Uses,Production

Chemical Properties

white to beige powder

Uses

One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.

Indications

Liothyronine sodium (Cytomel) is the sodium salt of the naturally occurring levorotatory isomer of T3. Liothyronine is generally not used for maintenance thyroid hormone replacement therapy because of its short plasma half-life and duration of action. The use of T3alone is recommended only in special situations, such as in the initial therapy of myxedema and myxedema coma and the short-term suppression of TSH in patients undergoing surgery for thyroid cancer. The use of T3 alone may also be useful in patients with the rare condition of 5'-deiodinase deficiency who cannot convert T4 to T3.

Definition

ChEBI: Liothyronine sodium is the sodium salt of liothyronine. Thought to be more active than levothyroxine and with a rapid (few hours) onset and short duration of action, liothyronine sodium is used in the treatment of hypothyroidism, particularly in cases of hypothyroid coma. It contains a 3,3',5-triiodo-L-thyroninate.

General Description

3,3′,5′-Triiodo-L-thyronine (T3) is an endocrine hormone produced by the thyroid gland and is regarded as an active thyroid hormone at cellular level. Thyroxine (T4) serves as a precursor for T3 and is generated in extrathyroidal tissues.

Liothyronine sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
LIOTHYRONINESODIUM,USP 3,3',5-Triiodothyronine sodium salt 3,5,3'-Triiodo-L-thyronine monosodium salt Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, monosodium salt, L- (8CI) Basoprocin Cynomel Cyomel Cytobin Cytomel sodium Cytomine Ibiothyron L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, monosodium salt (9CI) Sodium 3,3',5-triiodo-L-thyronine Sodium 3,5,3'-triiodothyronine Sodium L-3,3',5-triiodothyronine Sodium liothyronine Sodium L-triiodothyronine Sodium T3 Sodium triiodo-L-thyronine Sodium triiodothyronine Tertroxin Triiodothyronine sodium salt llothyronine sodium 3,3,5-TRIIODO-L-THYRONINE SODIUM SALT 98+% 3,3,5-TRIIODO-L -THYRONINE 95-98% SODIUM SALT CRYSTALLINE CELL CULTURE REAGENT 3,3′,5-Triiodo-L-thyronine sodium salt, >=99% 3,3',5-TRIIODO-L-THYRONINE SODIUM*GAMMA- IRRADIATED 3,3',5-TRIIODO-L-THYRONINE SODIUM Liothyronine Sodium USP28 L-Triiodothyronine, sodium salt Sodium L-liothyronine Sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate Liothyronine, T3, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine sodium salt L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, monosodium salt 3,3,5-TRIIODO-L -THYRONINE 95-98% SODIUM SALT CRYSTALLINE CELL CULTURE REAGENT GAMMA-IRRADIATED 3,3,5-TRIIODO-L -THYRONINE 95-98% SODIUM SALT CRYSTALLINE T3 Sodium Salt, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine Sodium Salt 3',5-Triiodo-L-thyronine sodium salt L-Triiodothyronine(T3) O-(4-hydroxy-3-iodophenyl)-3,5-diiodo- L-Tyrosine , sodium salt (1:1) (S)-2-AMINO-3-[4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONIC ACID SODIUM SALT SODIUM (S)-2-AMINO-3-[4-(4-HYDROXY-3-IODOPHENOXY)-3,5-DIIODOPHENYL]PROPIONATE T3 SODIUM SALT T3, NA O-[4-HYDROXY-3-IODOPHENYL]-3,5-DIIODO-L-TYROSINE SODIUM SALT 3,3',5-Triiodo-L-thyronine sodium salt≥ 98% (HPLC) LIOTHYRONINE SODIUM LIOTHYRONINE SODIUM SALT H-THY(3,3',5-I3)-ONA L-3,3',5-TRIIODOTHYRONINE, SODIUM SALT 3,3',5-TRIIODO-L-THYRONINE NA 3,3',5-TRIIODO-L-THYRONINE SODIUM SALT 3,3',5-TRIIODO-L-THYRONINE SODIUM SALT HYDRATE 3,3',5-TRIIODO-L-THYRONINE SODIUM*CELL C ULTURE TEST 3,3',5-Triiodo-L-thyronine, sodium salt,95% T3(3,3',5-Triiodo-L-thyronine) 3,3′,5-Triiodo-L-thyronine sodium salt,Liothyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine sodium salt, T3 Triiodothyronine-[13C6] hydrochloride (L-Liothyronine