Liothyronine sodium
- CAS No.
- 55-06-1
- Chemical Name:
- Liothyronine sodium
- Synonyms
- Triostat;Liothyronin sodiuM;Ibiot;Cyomel;T3, NA;Cytobin;Cynomel;Cytomine;Sodium T3;Tertroxin
- CBNumber:
- CB3195390
- Molecular Formula:
- C15H11I3NNaO4
- Molecular Weight:
- 672.96
- MOL File:
- 55-06-1.mol
- Modify Date:
- 2024/8/17 21:30:02
Melting point | 205 °C (dec.)(lit.) |
---|---|
alpha | 20 º (c=2,alcohol/1.2N HCl) |
RTECS | YP2836500 |
storage temp. | -20°C |
solubility | 4 M NH4OH in methanol: 125 g/5mL, clear, yellow-brown |
form | powder |
color | White to Pale Brown |
Water Solubility | Partly miscible in water. Soluble in dimethyl sulfoxide, methanol, sodium hydroxide and ethanol. Practically insoluble in most other organic solvents. |
Sensitive | Light Sensitive |
Merck | 5510 |
BRN | 8179867 |
InChI | InChI=1/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/s3 |
InChIKey | SBXXSUDPJJJJLC-ZLBVLXFENA-M |
SMILES | C1(C(I)=CC(C[C@H](N)C([O-])=O)=CC=1I)OC1=CC=C(O)C(I)=C1.[Na+] |&1:6,r| |
CAS DataBase Reference | 55-06-1(CAS DataBase Reference) |
EPA Substance Registry System | L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-, monosodium salt (55-06-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05 |
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Signal word | Danger | |||||||||
Hazard statements | H314-H290 | |||||||||
Precautionary statements | P501-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405 | |||||||||
Hazard Codes | Xn | |||||||||
Risk Statements | 20/21/22 | |||||||||
Safety Statements | 22-24/25-36 | |||||||||
WGK Germany | 3 | |||||||||
F | 3-8-10 | |||||||||
HS Code | 29379000 | |||||||||
NFPA 704 |
|
Liothyronine sodium price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | T6397 | 3,3′,5-Triiodo-L-thyronine sodium salt powder, BioReagent, suitable for cell culture | 55-06-1 | 100MG | ₹7653.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T6397 | 3,3′,5-Triiodo-L-thyronine sodium salt powder, BioReagent, suitable for cell culture | 55-06-1 | 250MG | ₹15436.45 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T6397 | 3,3′,5-Triiodo-L-thyronine sodium salt powder, BioReagent, suitable for cell culture | 55-06-1 | 1G | ₹38699.38 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | T5516 | 3,3′,5-Triiodo-L-thyronine sodium salt γ-irradiated, powder, suitable for, suitable for cell culture | 55-06-1 | 1MG | ₹9266.2 | 2022-06-14 | Buy |
Liothyronine sodium Chemical Properties,Uses,Production
Chemical Properties
white to beige powder
Uses
One of the hormones produced by the thyroid gland that is involved in the maintenance of metabolic homeostasis. Also produced in peripheral tissues as the active metabolite of Thyroxine.
Indications
Liothyronine sodium (Cytomel) is the sodium salt of the naturally occurring levorotatory isomer of T3. Liothyronine is generally not used for maintenance thyroid hormone replacement therapy because of its short plasma half-life and duration of action. The use of T3alone is recommended only in special situations, such as in the initial therapy of myxedema and myxedema coma and the short-term suppression of TSH in patients undergoing surgery for thyroid cancer. The use of T3 alone may also be useful in patients with the rare condition of 5'-deiodinase deficiency who cannot convert T4 to T3.
Definition
ChEBI: Liothyronine sodium is the sodium salt of liothyronine. Thought to be more active than levothyroxine and with a rapid (few hours) onset and short duration of action, liothyronine sodium is used in the treatment of hypothyroidism, particularly in cases of hypothyroid coma. It contains a 3,3',5-triiodo-L-thyroninate.
General Description
3,3′,5′-Triiodo-L-thyronine (T3) is an endocrine hormone produced by the thyroid gland and is regarded as an active thyroid hormone at cellular level. Thyroxine (T4) serves as a precursor for T3 and is generated in extrathyroidal tissues.
Liothyronine sodium Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Apotex Pharmachem India Pvt Ltd | +91-8022891034 +91-8022891000 | Karnataka, India | 109 | 58 | Inquiry |
Biophore India Pharmaceuticals Pvt Ltd | +91-9100031592 +91-9030907714 | Telangana, India | 134 | 58 | Inquiry |
Besil Chem LLP | +91-7760252666 +91-9880731835 | Bangalore, India | 163 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Allmpus Laboratories Pvt Ltd | +91-9518738415 +91-9167862134 | Maharashtra, India | 657 | 58 | Inquiry |
AZICO BIOPHORE INDIA PVT LTD | 0091-40-2381-2709 | New Delhi, India | 5 | 58 | Inquiry |
AZICO BIOPHORE INDIA PRIVATE LIMITED | 0091-40-2381-2709 | New Delhi, India | 3 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
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