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Sulprostone

Sulprostone Structure
CAS No.
60325-46-4
Chemical Name:
Sulprostone
Synonyms
sch286;SHB-286;Nalador;ZK-57671;CP-34089;CP-34086;SULPROSTONE;Sulprostone USP/EP/BP;Sulprostone >=95% (HPLC), oil;Sulprostone in 5mg/ml Methyl Acetate
CBNumber:
CB3224098
Molecular Formula:
C23H31NO7S
Molecular Weight:
465.56
MOL File:
60325-46-4.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

Sulprostone Properties

Melting point 79.25°C
Density 1.1918 (rough estimate)
refractive index 1.5650 (estimate)
storage temp. -20°C
solubility DMSO: >5 mg/mL
pka 4.63±0.40(Predicted)
form solid
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Danger
Hazard statements  H315-H319-H335-H360
Precautionary statements  P201-P302+P352-P305+P351+P338-P308+P313
Hazard Codes  T
Risk Statements  60-36/37/38
Safety Statements  53-22-36/37-45
WGK Germany  3
RTECS  MJ8810000
Toxicity LD50 intraperitoneal in mouse: 18mg/kg
NFPA 704
3
2 0

Sulprostone price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S8692 Sulprostone ≥95% (HPLC), oil 60325-46-4 1MG ₹17980.33 2022-06-14 Buy
Sigma-Aldrich(India) S8692 Sulprostone ≥95% (HPLC), oil 60325-46-4 5MG ₹71813.05 2022-06-14 Buy
Product number Packaging Price Buy
S8692 1MG ₹17980.33 Buy
S8692 5MG ₹71813.05 Buy

Sulprostone Chemical Properties,Uses,Production

Description

Sulprostone is a metabolism resistant synthetic analog of PGE2. It is a selective agonist for EP3 receptors with a Ki value of 0.35 nM at the human recombinant EP3-III receptor and an IC50 of 0.01 μM for the inhibition of PGE2 binding. Sulprostone is a potent stimulator of uterine smooth muscle contractions with high abortifacient activity.

Uses

Sulprostone is a selective agonist of the PGE2 receptor.

World Health Organization (WHO)

Sultopride, a neuroleptic indicated for the treatment of acute and chronic psychoses, was introduced on the market in 1976. In the early 1990s, its use was associated with cardiac arrhythmias, some of which were fatal. This led the regulatory authority in France to take restrictive action on the product. Sultopride continues to be marketed in several other countries.

Sulprostone Preparation Products And Raw materials

Raw materials

Preparation Products

Sulprostone Suppliers

Global( 61)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 9077 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 19947 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20366 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Shanghai Easy CDMO Co.,Ltd 021-61734564 China 10010 58 Inquiry
(1r-(1-alpha(z),2-beta(1e,3r*),3-alpha))--n-(methylsulfonyl) 16-phenoxy-17,18,19,20tetranorprostaglandine(sub2)methylsulfonylamide 16-phenoxy-omega-17,18,19,20-tetranorpge-2methylsulfonylamide 16-phenoxy-omega-17,18,19,20-tetranorprostaglandine2methylsulfonylamide N-(METHYLSULFONYL)-9-OXO-11ALPHA,15R-DIHYDROXY-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-AMIDE SHB-286 SULPROSTONE ZK-57671 5-heptenamide,7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl) sch286 (5Z,11ALPHA,13E,15R)-11,15-DIHYDROXY-9-OXO-16-PHENOXY-17,18,19,20-TETRANORPROSTA-5,13-DIENOIC ACID METHANE SULFONAMIDE CP-34089 (5Z,11alpha,13E,15R)-11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide CP-34089, SHB-286, ZK-57671, (5Z,11α,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide (5Z,11a,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide Nalador CP-34086 (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide (5z,11α,13e,15r)-11,15-dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3R)-3-hydroxy-4-(phenoxy)but-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide Sulprostone USP/EP/BP Sulprostone >=95% (HPLC), oil 5-Heptenamide, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-, (5Z)- Sulprostone in 5mg/ml Methyl Acetate 60325-46-4 C23H31NO7S Analytical Chromatography Product Catalog Analytical Standards Chromatography Drug Standards Forensic and Veterinary Standards