Atropic acid
- CAS No.
- 492-38-6
- Chemical Name:
- Atropic acid
- Synonyms
- NSC 20987;ATROPIC ACID;Atropic Acid >10029 ATROPIC ACID;2-PHENYLACRYLIC ACID;Cinacalcet ImpurityI;Α-PHENYLACRYLIC ACID;Atropic acid，492-38-6;2-Phenylpropenoic acid;Ipratropium Impurity D
- CBNumber:
- CB3224700
- Molecular Formula:
- C9H8O2
- Molecular Weight:
- 148.16
- MOL File:
- 492-38-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/16 18:25:32
| Melting point | 106-107° |
|---|---|
| Boiling point | bp ~267° with partial decompn |
| Density | 1.0061 (rough estimate) |
| refractive index | 1.5049 (estimate) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.86±0.11(Predicted) |
| color | White to Off-White |
| Water Solubility | 1.3g/L(20 ºC) |
| Merck | 14,874 |
| Stability | Light Sensitive |
| InChIKey | ONPJWQSDZCGSQM-UHFFFAOYSA-N |
| CAS DataBase Reference | 492-38-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzeneacetic acid, «alpha»-methylene-(492-38-6) |
| EPA Substance Registry System | Benzeneacetic acid, .alpha.-methylene- (492-38-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39 |
| HS Code | 29163990 |
Atropic acid price More Price(2)
Atropic acid Chemical Properties,Uses,Production
Chemical Properties
White to Off-White Solid.
Uses
Atropic acid is an Impurity of Ipratropium bromide and Atropine Sulfate. Atropic acid and β,β-dimethylatropic acid are plant growth regulators.
Preparation
The synthesis of atropic acid involves several steps. Firstly, tropic acid is oxidized with hot KMnO4 to form benzoic acid. Secondly, tropic acid reacted with HBr to produce C9H9O2Br. Thirdly, C9H9O2Br is reacted with alcoholic KOH to yield atropic acid, C9H8O2. Finally, atropic acid is catalytically hydrogenated to form hydratropic acid, C9H10O2.
Reactions
Atropic acid is formed by the dehydration of tropic acid. Hence addition of water to atropic acid gives tropic acid.
Atropic acid, on oxidation yields benzoic acid. The formation of benzoic acid reveals that atropic acid and tropic acid contain atleast one benzene nucleus with a side chain containing carboxylic acid in their structure.
As atropic acid is an unsaturated acid it mean atropic acid may be either structure (I) or (II) .
Hence, the structure (II) is atropic acid which is confirmed by oxidation with KMnO4 to form phenylglyoxal.
Atropic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Anant Pharmaceuticals Pvt Ltd | +91-8550986868 +91-9485998001 | Haryana, India | 461 | 58 | Inquiry |
| RANI LIFE SCIENCES PVT LTD | +91-8008797507 +91-8008797507 | Hyderabad, India | 37 | 58 | Inquiry |
| GLP Pharma Standards | +91 9866074638 | Hyderabad, India | 1644 | 58 | Inquiry |
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| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Seine Pharma Private Limited | 08069033811Ext 842 | Hyderabad, India | 78 | 58 | Inquiry |
| Taj Mahal Vision Chemicals Private Limited | 07942557933 | Mumbai, India | 206 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
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