2-Methyl-3-biphenylmethanol
- CAS No.
- 76350-90-8
- Chemical Name:
- 2-Methyl-3-biphenylmethanol
- Synonyms
- Bifenthrin alcohol;Biphenyl alcohol;biphenylmethyanol;2-METHYLBIPHENYL-3-METHANOL;2-methyl-3-biphenylmethyanol;3-HYDROXYMETHYL-2-METHYLBIPHENYL;2-Methyl-3-biphenylm;2-METHYL-3-BIPHENYLMETHANOL;2-Methyl-3-phenylbenzyl Alcohol;2-Methyl-3-hydroxymethyldiphenyl
- CBNumber:
- CB3339318
- Molecular Formula:
- C14H14O
- Molecular Weight:
- 198.26
- MOL File:
- 76350-90-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/11 13:42:12
| Melting point | 73-76 °C(lit.) |
|---|---|
| Boiling point | 330.9±11.0 °C(Predicted) |
| Density | 1.072±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 14.28±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C14H14O/c1-11-13(10-15)8-5-9-14(11)12-6-3-2-4-7-12/h2-9,15H,10H2,1H3 |
| InChIKey | BGTLHJPGBIVQLJ-UHFFFAOYSA-N |
| SMILES | C1(C2=CC=CC=C2)=CC=CC(CO)=C1C |
| CAS DataBase Reference | 76350-90-8(CAS DataBase Reference) |
| EPA Substance Registry System | [1,1'-Biphenyl]-3-methanol, 2-methyl- (76350-90-8) |
2-Methyl-3-biphenylmethanol Chemical Properties,Uses,Production
Description
2-Methyl-3-biphenylmethanol is a pharmaceutical intermediate and organic chemical synthesis reagent, which can be used in the preparation of drugs such as Bifenthrin and PD-L1 inhibitors, and also in the synthesis of other organic compounds such as 2-methyl-3-phenylphenethylboronic acid pinacol ester, biphenyl-1,2,3-triazole couplings and biphenyl alcohols.
Chemical Properties
white to light yellow crystal powde
Uses
Bifenthrin intermediate.
Synthesis
Carrying out a Suzuki coupling reaction between 3-bromo-2-methylbenzoic acid and phenyl substituted boric acid or phenyl substituted borate to obtain 3-phenyl-2-methylbenzoic acid, and then carrying out a reduction reaction to obtain 2-Methyl-3-biphenylmethanol, wherein the Suzuki coupling reaction is carried out at 10-150 DEG C for 1-12 hours under the action of an alkali. 3-phenyl-2-methylbenzoic acid can be directly reduced with a reducing agent such as borane and lithium aluminium hydride to obtain 2-Methyl-3-biphenylmethanol.
2-Methyl-3-biphenylmethanol Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Aether Industries Limited | +91-261-6603130 +91-2616603130 | Gujarat, India | 145 | 58 | Inquiry |
| VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2096 | 58 | Inquiry |
| Pacific Agencies | 08048372547Ext 801 | Mumbai, India | 135 | 58 | Inquiry |
| ChemOrbit International | 91-40-23712139 | Hyderabad, India | 264 | 58 | Inquiry |
| Aether Industries Limited | 91-261-3303000 | Gujarat, India | 27 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Akshaya Pure Chemicals | 08048372572Ext 130 | Mumbai, India | 36 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Aether Industries Limited | 58 |
| VASIN BIO LIFE SCIENCES PVT LTD | 58 |
| Pacific Agencies | 58 |
| ChemOrbit International | 58 |
| Aether Industries Limited | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| CHEMSWORTH | 30 |
| A.J Chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| Akshaya Pure Chemicals | 58 |
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