ChemicalBook > Product Catalog >Biochemical Engineering >Condensing agent >4,4'-Dimethoxytrityl chloride
4,4'-Dimethoxytrityl chloride
- CAS No.
- 40615-36-9
- Chemical Name:
- 4,4'-Dimethoxytrityl chloride
- Synonyms
- DMT;DMT-CL;4,4'-(Chloro(phenyl)Methylene)bis(Methoxybenzene);4,4-DIMETHOXYTRITYL CHLORIDE;Dimethoxy Trityl Chloride;EPB49;DMTrCl;DMT-Cl)D;DMTRT-CL;NSC 89782
- CBNumber:
- CB3442487
- Molecular Formula:
- C21H19ClO2
- Molecular Weight:
- 338.83
- MOL File:
- 40615-36-9.mol
- Modify Date:
- 2025/2/23 21:28:46
| Melting point | 123-125 °C |
|---|---|
| Boiling point | 455.07°C (rough estimate) |
| Density | 1.0887 (rough estimate) |
| vapor pressure | 0Pa at 20℃ |
| refractive index | 1.5330 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Powder |
| color | Pink |
| Water Solubility | Soluble in chloroform and methanol. Partially soluble in water |
| Sensitive | Moisture Sensitive |
| BRN | 2471942 |
| Stability | Hygroscopic, Moisture Sensitive |
| InChIKey | JBWYRBLDOOOJEU-UHFFFAOYSA-N |
| LogP | 5.74 at 20℃ |
| CAS DataBase Reference | 40615-36-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Methane, chlorobis(p-methoxyphenyl)phenyl-(40615-36-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H317-H335-H411 | |||||||||
| Precautionary statements | P260-P271-P273-P280-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-34 | |||||||||
| Safety Statements | 22-24/25-37/39-26-36-45-36/37/39 | |||||||||
| RIDADR | 3261 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| HS Code | 29093090 | |||||||||
| Toxicity | A hallucinogenic (psychedelic) agent that may catalyze the onset of emotional problems or psychosis in predisposed individuals. DMT is perhaps one of the least studied of the hallucinogens. It causes perceptual alterations and illusions, including changes in touch, taste, and odor. The thinking process is substantially altered; there are hallucinations and loss of contact with reality. There have been no overdose deaths attributed to the direct effects of DMT. The drug is very short-acting, with a duration of effect of about half an hour or less. | |||||||||
| NFPA 704 |
|
4,4'-Dimethoxytrityl chloride price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 38827 | 4,4′-Dimethoxytriphenylmethyl chloride ≥97.0% (HPLC) | 40615-36-9 | 10G | ₹6375.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 38827 | 4,4′-Dimethoxytriphenylmethyl chloride ≥97.0% (HPLC) | 40615-36-9 | 50G | ₹27625.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 100013 | 4,4′-Dimethoxytrityl chloride 95% | 40615-36-9 | 5G | ₹2370.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 100013 | 4,4′-Dimethoxytrityl chloride 95% | 40615-36-9 | 25G | ₹9147.13 | 2022-06-14 | Buy |
| ALFA India | ALF-A11626-22 | 4,4'-Dimethoxytrityl chloride, 97% | 40615-36-9 | 100g | ₹18992 | 2022-05-26 | Buy |
4,4'-Dimethoxytrityl chloride Chemical Properties,Uses,Production
Chemical Properties
4,4'-Dimethoxytrityl chloride is pink powder
Uses
4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.
Purification Methods
DMT crystallises from cyclohexane/acetyl chloride as the hydrochloride. Dry it over KOH pellets in a desiccator. When dissolved in *C6H6 and air is blown through, HCl is removed. It crystallises from Et2O. [Baeyer & Villiger Chem Ber 36 2788 1903, Smith et al. J Am Chem Soc 84 430 1962, Smith et al. J Am Chem Soc 85 3821 1963.] Ifit has hydrolysed considerably (see OH in IR), then repeat the crystallisation from cyclohexane/acetyl chloride — excess of AcCl is removed in a vacuum over KOH, then recrystallise it from Et2O. [Beilstein 6 IV 1042.]
4,4'-Dimethoxytrityl chloride Preparation Products And Raw materials
Raw materials
Preparation Products
5''-O-(4,4''-Dimethoxytrityl)-inosine
5'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE
DMT-DCYTIDINE (N6-BENZOYL) CYANOETHYL PHOSPHORAMIDITE)
5'-O-(4,4'-DIMETHOXYTRITYL)-N4-BENZOYL-5-METHYL-2'-DEOXYCYTIDINE
5'-O-(4,4'-DIMETHOXYTRITYL)-N4-ACETYL-2'-DEOXYCYTIDINE
DMT-dG(dmf) Phosphoramidite
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
5'-O-Dimethoxytrityl-N-benzoyl-desoxycytidine
Acetamide, N-[3-[bis(4-methoxyphenyl)phenylmethoxy]-2-hydroxypropyl]-2,2,2-trifluoro-
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (S)- (9CI)
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Global( 642)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
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| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| ADVENT CHEMBIO PRIVATE LIMITED | 58 |
| JUVENUS DRUGS | 58 |
| ChemGenes India Pvt Ltd | 58 |
| Otto Chemie Pvt Ltd | 58 |
| Innovassynth Technologies (I) Ltd. | 58 |
| RPN ORGANICS PVT LTD | 58 |
| JSK Chemicals | 58 |
| Chempure | 58 |
| Clearsynth Labs | 58 |
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-Dimethoxytrityl chloride
99% 44’Dimethoxytriphenylmethyl chlide 40615-36-9 CAS NO.40615-36-9
4,4'-Dimethoxytrityl chloride
4,4'-Dimethoxytrityl Chloride [Hydroxyl Protecting Agent
NSC 89782