Pyraclofos
![Pyraclofos Structure](CAS/GIF/77458-01-6.gif)
- CAS No.
- 77458-01-6
- Chemical Name:
- Pyraclofos
- Synonyms
- TIA 230;SC 1069;OMS3034;VOLTAGE;BOLTAGE;VOLTAGE(R);BOLTAGE(R);STARLEX(R);PYRACLOFOS;Pyraclofos Standard
- CBNumber:
- CB3681581
- Molecular Formula:
- C14H18ClN2O3PS
- Molecular Weight:
- 360.8
- MOL File:
- 77458-01-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/4 17:34:42
Melting point | 25°C |
---|---|
Boiling point | 164approximate 164℃(0.013hPa) |
Density | 1.27 |
vapor pressure | 1.6×10-6 Pa (20 °C) |
storage temp. | 0-6°C |
Water Solubility | 33 |
form | liquid |
Specific Gravity | 1.271 (28℃) |
CAS DataBase Reference | 77458-01-6(CAS DataBase Reference) |
EPA Substance Registry System | Phosphorothioic acid, O-[1-(4-chlorophenyl)-1H-pyrazol- 4-yl] O-ethyl S-propyl ester(77458-01-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS06 |
---|---|
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
Hazard Codes | Xi,Xn |
Risk Statements | 22 |
RIDADR | 3018 |
RTECS | TE8346000 |
HazardClass | 6.1(b) |
PackingGroup | III |
HS Code | 29331990 |
Pyraclofos Chemical Properties,Uses,Production
Uses
Pyraclofos is used to control Lepidoptera, Coleoptera, mites and nematodes in fruit, vegetables, ornamentals and forestry. It has also been used in a human health application to control filarial worms.
Metabolic pathway
Pyraclofos is apparently subjected in insects to a metabolic activation to yield a more active acetylcholinesterase inhibitor which is possibly a thiooxidized metabolite. The compound is very rapidly degraded in mammals to inactive metabolites via P-O-aryl, P-O-alkyl and P-S-alkyl cleavage which explains its favourable selective toxicity. In both mammals and plants the principal degradative route is via P-O-aryl cleavage to give 1-(4-chlorophenyl)-4-hydroxypyrazolwe hich is rapidly conjugated.
Metabolism
Pyraclofos is metabolized to an active AChE inhibitor, probably by the oxidation of the sulfur atom in the phosphorothiolate linkage. The half-life in soil is 3–38 d, depending on soil type.
Pyraclofos Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
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