NS1643

NS1643 Structure
CAS No.
448895-37-2
Chemical Name:
NS1643
Synonyms
NS1643, >98%;NS-1643;NS 1643;NS-1643;NS1643;NS 1643;1,3-bis(5-(trifluoromethyl)-2-hydroxyphenyl)urea;N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea;Urea, N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]-;KcsA,NS1643,NS 1643,Potassium Channel,Inhibitor,inhibit,NS-1643,Autophagy
CBNumber:
CB3972395
Molecular Formula:
C15H10F6N2O3
Molecular Weight:
380.24
MOL File:
448895-37-2.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

NS1643 Properties

Boiling point 342.3±42.0 °C(Predicted)
Density 1.626±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility DMSO: ≥20mg/mL
pka 6.84±0.13(Predicted)
form solid
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301-H319
Precautionary statements  P301+P310+P330-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22-36
Safety Statements  26
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
NFPA 704
0
2 0

NS1643 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) N0663 NS1643 ≥98% (HPLC), solid 448895-37-2 5MG ₹19809.75 2022-06-14 Buy
Product number Packaging Price Buy
N0663 5MG ₹19809.75 Buy

NS1643 Chemical Properties,Uses,Production

Uses

NS 1643 is a human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator.

Biological Activity

Human ether-a-go-go related gene (hERG) K + channel activator (EC 50 = 10.5 μ M). Exhibits different molecular mechanisms of action at hERG1 and hERG2 channels. Displays antiarrhythmic activity in vitro .

NS1643 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 78)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
SHANGHAI T&W PHARMACEUTICAL CO., LTD. +86-021-61551413 +8618813727289 China 5738 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
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Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea NS-1643;NS 1643 NS1643, >98% NS-1643;NS1643;NS 1643 Urea, N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]- 1,3-bis(5-(trifluoromethyl)-2-hydroxyphenyl)urea KcsA,NS1643,NS 1643,Potassium Channel,Inhibitor,inhibit,NS-1643,Autophagy 448895-37-2 C15H10F6N2O3