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NS1643

NS1643 Structure
  • ₹19809.75
  • Product name: NS1643
  • CAS: 448895-37-2
  • MF: C15H10F6N2O3
  • MW: 380.24
  • EINECS:
  • MDL Number:MFCD08705418
  • Synonyms:N,N'-Bis[2-hydroxy-5-(trifluoromethyl)phenyl]urea;NS-1643;NS 1643;NS1643, >98%;NS-1643;NS1643;NS 1643;Urea, N,N'-bis[2-hydroxy-5-(trifluoromethyl)phenyl]-;1,3-bis(5-(trifluoromethyl)-2-hydroxyphenyl)urea;KcsA,NS1643,NS 1643,Potassium Channel,Inhibitor,inhibit,NS-1643,Autophagy
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Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberN0663
  • Product descriptionNS1643 ≥98% (HPLC), solid
  • Packaging5MG
  • Price₹19809.75
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) N0663 NS1643 ≥98% (HPLC), solid 5MG ₹19809.75 2022-06-14 Buy

Properties

Boiling point :342.3±42.0 °C(Predicted)
Density :1.626±0.06 g/cm3(Predicted)
storage temp. :Inert atmosphere,2-8°C
solubility :DMSO: ≥20mg/mL
pka :6.84±0.13(Predicted)
form :solid
color :white to off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

NS 1643 is a HERG(hERG K+ channel) activator, such as KCNH6. Displays different molecular mechanisms of action at hERG1 and hERG2 channels. Exhibits antiarrhythmic activity in vitro.

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