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APAMIN

APAMIN Structure
  • ₹33092.03
  • Product name: APAMIN
  • CAS: 24345-16-2
  • MF: C79H131N31O24S4
  • MW: 2027.34
  • EINECS:246-182-7
  • MDL Number:MFCD00167944
  • Synonyms:APAMIN, BEE VENOM;APAMIN (HONEY BEE, APIS MELIFERA);apamine ;APAMIN FROM BEE VENOM;APAMIN FROM HONEY BEE VENOM;M.W. 2027.34 C79H131N31O24S4;L-Cys-L-Asn-L-Cys-L-Lys-L-Ala-L-Pro-L-Glu-L-Thr-L-Ala-L-Leu-L-Cys-L-Ala-L-Arg-L-Arg-L-Cys-L-Gln-L-Gln-L-His-NH2;CYS-ASN-CYS-LYS-ALA-PRO-GLU-THR-ALA-LEU-CYS-ALA-ARG- ARG-CYS-GLN-GLN-HIS-NH2(DISULFIDE BRIDGE:CYS1-CYS11, CYS3-CYS15)
Price1 Properties Safety Information Description
1 prices
Selected condition：

Brand

  • Sigma-Aldrich(India)

Package

  • 0.5MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberA9459
  • Product descriptionApamin synthetic, ≥97% (HPLC)
  • Packaging0.5MG
  • Price₹33092.03
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) A9459 Apamin synthetic, ≥97% (HPLC) 0.5MG ₹33092.03 2022-06-14 Buy

Properties

Boiling point :847.17°C (rough estimate)
Density :1.63
refractive index :1.5530 (estimate)
storage temp. :-20°C
solubility :0.05 M acetic acid: 5 mg/mL, clear, colorless to faintly yellow
form :White solid with dark tan
color :White to off-white
Water Solubility :Soluble to 1 mg/ml in water
Merck :13,732

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P342+P311 IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

Description

Apamin is an 18 amino acid peptide toxin found in bee venom. It is a potent blocker of small conductance Ca2+-activated K+ (SK, KCa2) channels that is more effective at SK2 than SK1 and SK3 (IC50 values are 0.06-0.4, 1-12, and 1-13 nM, respectively). It is ineffective against SK4 at 1 μM. Apamin is used to elucidate the roles of these channels in cells and tissues expressing SK channels, including neurons, vascular endothelium, bladder smooth muscle, and certain types of cancer cells.

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Suppliers and manufacturers

career henan chemical co
Apamin
₹9.80 /1KG
Apamin CAS:24345-16-2
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