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Ranimustine

Ranimustine Structure
CAS No.
58994-96-0
Chemical Name:
Ranimustine
Synonyms
MCNU;Cymerin;CyMerine;Thymerin;NSC 270516;RANIMUSTINE;Ranomustine;NSC-0270516;RCL L16,919-6;Ranimustine USP/EP/BP
CBNumber:
CB4269380
Molecular Formula:
C10H18ClN3O7
Molecular Weight:
327.72
MOL File:
58994-96-0.mol
MSDS File:
SDS
Modify Date:
2023/5/15 10:43:54

Ranimustine Properties

Melting point 111-112°
alpha D20 +93.2° (c = 0.5 in methanol) (Kimura); D25 +73.2° (c = 0.3 in methanol) (Kimura, Sekine)
Density 1.69±0.1 g/cm3(Predicted)
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 10.59±0.46(Predicted)
color Off-White to Pale Yellow
CAS DataBase Reference 58994-96-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Toxicity LD50 in male rats (mg/kg): 42 i.p., 42 i.v., 50 orally (Kimura)

Ranimustine Chemical Properties,Uses,Production

Description

Ranimustine, a new nitrosourea derivative, is a water soluble antitumor agent with low hematological toxicity and diabetogenic effect. It is reportedly effective in the treatment of hematologic malignancies, especially the myeloproliferative disorders.

Uses

Glucocorticoid with low systemic absorption anti-inflammatory agent

Ranimustine Preparation Products And Raw materials

Global( 35)Suppliers
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CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25247 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49999 58 Inquiry
Watson Biotechnology Co.,Ltd +86-18186686046 +86-18186686046 China 5823 58 Inquiry
Facus Pharmaceutical Co.,Ltd. +86-(0)574-62378411 China 293 39 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24016 58 Inquiry
Beijing Qinling Pharmaceutical Co., Ltd. 010-61241352 18901327973 China 4173 58 Inquiry
Hangzhou Jinghao Biotechnology Co., LTD 17513242016 17513242016 China 2801 58 Inquiry
1-(2-chloroethyl)-1-nitroso-3-[[(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-methoxy-oxan-2-yl]methyl]urea Cymerin MCNU Methyl 6-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-6-deoxy-α-D-glucopyranoside NSC-0270516 Ranomustine Thymerin Methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-α-D-glucopyranoside CyMerine NSC 270516 RANIMUSTINE RCL L16,919-6 α-D-Glucopyranoside, methyl 6-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-6-deoxy- Ranimustine USP/EP/BP 58994-96-0 C10H18ClN3O7