DESIPRAMINE HYDROCHLORIDE
![DESIPRAMINE HYDROCHLORIDE Structure](CAS/GIF/58-28-6.gif)
- CAS No.
- 58-28-6
- Chemical Name:
- DESIPRAMINE HYDROCHLORIDE
- Synonyms
- ex4355;g35020;jb8181;Petylyl;Nortimil;RMI-9384A;norpramin;pertofran;nsc-114901;pertofrane
- CBNumber:
- CB4723947
- Molecular Formula:
- C18H23ClN2
- Molecular Weight:
- 302.84
- MOL File:
- 58-28-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H302-H315-H317-H319-H334-H335 |
Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
Hazard Codes | Xn,T,F |
Risk Statements | 22-36/37/38-42/43-48/23/24/25-23/24/25-11-39/23/24/25 |
Safety Statements | 7-16-36/37-45-26-24-22 |
RIDADR | UN 1230 3/PG 2 |
WGK Germany | 3 |
RTECS | HO0525000 |
HS Code | 2933996100 |
Toxicity | LD50 in mice, rats (mg/kg): 500, 385 orally; 94, 48 i.p.; 420, 183 s.c. (Eriksoo, Rohte) |
DESIPRAMINE HYDROCHLORIDE price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D3900 | Desipramine hydrochloride ≥98% (TLC), powder | 58-28-6 | 1G | ₹5174.35 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1723 | Desipramine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 58-28-6 | 400MG | ₹13769.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D3900 | Desipramine hydrochloride ≥98% (TLC), powder | 58-28-6 | 5G | ₹18857.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D-906 | Desipramine hydrochloride solution 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant? | 58-28-6 | 1ML | ₹2407.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D3900 | Desipramine hydrochloride ≥98% (TLC), powder | 58-28-6 | 25G | ₹73296.08 | 2022-06-14 | Buy |
DESIPRAMINE HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White To Off-White Solid
Uses
Desipramine hydrochloride has been used:
- to prevent norepinephrine neuron degeneration and to maximize uptake into DA neurons
- to protect unselective damage to the?noradrenergic system
- as a norepinephrine re-uptake inhibitor to treat rats for lesioning
Definition
ChEBI: The hydrochloride salt of desipramine.
General Description
The structure and salient properties of desipramine hydrochloride,10,11-dihydro-N-methyl-5H-dibenz[b,f]azepine-5-propanamine monohydrochloride, 5-(3-methylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride(Norpramin, Pertofrane), are discussed under the heading,Imipramine. Among tricyclics, desipramine would be consideredwhen few anticholinergic effects or a low level of sedationare important. It is a SNERI.
Biological Activity
Tricyclic antidepressant that is a selective inhibitor of noradrenalin transporters (K i values are 4, 61 and 78720 nM for NET, SERT and DAT transporters respectively).
Safety Profile
Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by ingestion: decreased urine volume, sodium level changes, chlorine level changes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of NO, and HCI.
DESIPRAMINE HYDROCHLORIDE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
Chong Med Store | 08421368815 | Maharashtra, India | 1 | 58 | Inquiry |
Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
Euroasia Trans Continental | +91 22 56349035-36 | New Delhi, India | 519 | 47 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
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