Hordenine
- CAS No.
- 539-15-1
- Chemical Name:
- Hordenine
- Synonyms
- Hordenin;Hordeine;Anhalin;Cactine;Anhaline;Hordetin;Ordenina;Ordenine;Eremursin;Hordenine
- CBNumber:
- CB4747471
- Molecular Formula:
- C10H15NO
- Molecular Weight:
- 165.23
- MOL File:
- 539-15-1.mol
- Modify Date:
- 2024/7/2 8:55:09
| Melting point | 117-118° |
|---|---|
| Boiling point | bp11 173° |
| Density | 1.0203 (rough estimate) |
| refractive index | 1.4820 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 10.05±0.26(Predicted) |
| color | Pale Yellow to Dark Beige |
| Merck | 14,4746 |
| BRN | 2207615 |
| LogP | 1.400 (est) |
| CAS DataBase Reference | 539-15-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Phenol, 4-[2-(dimethylamino)ethyl]-(539-15-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36-43 | |||||||||
| Safety Statements | 26-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29222990 | |||||||||
| NFPA 704 |
|
Hordenine price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 04476 | Hordenine ≥97.0% (HPLC) | 539-15-1 | 100MG | ₹6083.65 | 2022-06-14 | Buy |
| Sigma-Aldrich | 61207 | Hordenine analytical standard | 539-15-1 | 50MG | ₹8692.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 61207 | Hordenine analytical standard | 539-15-1 | 50MG | ₹8692.48 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 04476 | Hordenine ≥97.0% (HPLC) | 539-15-1 | 1G | ₹32377.58 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H1351 | Hordenine min. 98.0 % | 539-15-1 | 1G | ₹9400 | 2022-05-26 | Buy |
Hordenine Chemical Properties,Uses,Production
Description
Hordenine (Item No. 21626) is a naturally occurring alkaloid found in a variety of plants, most commonly germinated barley (Hordeum species) from which the name is derived, and is structurally classified as a phenethylamine. It is biosynthesized by the step-wise double methylation of tyramine . Hordenine binds to and activates the dopamine D2 receptor (Ki = 13 μM) but antagonizes D2 receptor β-arrestin recruitment. It inhibits tyrosinase activity and expression at concentrations ≥ 50 μM resulting in reduced melanin accumulation in human melanocytes. Hordenine is present in significant amounts in beer and can be measured in serum in the free form, for up to 2 hours, and the glucuronidated form, for up to 6 hours, after beer consumption. This product is intended for research and forensic applications.
Chemical Properties
Light yellow solid
Uses
Hordenine is suitable to study the effect of reed canary grass alkoloids on in vito digestibility. It is also suitable for use as a standard to identify endogenous hordenine in ungerminated and germinated barley by HPLC/diode array detection analysis. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids.
Purification Methods
Crystallise Hordenine from EtOH or H2O and sublime it at 105o/5mm. The 4,4’-dichlorodiphenyl disulfimide salt has m 145-146o (from Me2CO/H2O) [Runge et al. Chem Ber 88 50 1955]. [Beilstein 13 H 626, 13 I 236, 13 II 356, 13 III 1640, 13 IV 1790.]
Hordenine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12456 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5907 | 58 | Inquiry |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
| Hebei Shengyang Water Conservancy Engineering Co., Ltd. | +8615373025980 | China | 871 | 58 | Inquiry |
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