ChemicalBook > Product Catalog >Biochemical Engineering >Chinese Herbs >Protopanaxadiol

Protopanaxadiol

Protopanaxadiol Structure
CAS No.
7755-01-3
Chemical Name:
Protopanaxadiol
Synonyms
Protopanaxadiol;20R-Protopanaxadiol;(20R)-Protopanaxadiol;20R-Betulafolienetriol;Protopanaxadiol USP/EP/BP;PROTOVERATRINE A+B (RG)(CALL);(20R)-Dammar-24-ene-3β,12β,20-triol;(20R)-5α-Dammar-24-ene-3β,12β,20-triol;Dammar-24-ene-3,12,20-triol, (3β,12β,20R)-;Protopanaxadiol, 98%, from Panax ginseng C. A. Mey.
CBNumber:
CB51040709
Molecular Formula:
C30H52O3
Molecular Weight:
460.73
MOL File:
7755-01-3.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:10

Protopanaxadiol Properties

Boiling point 559.5±40.0 °C(Predicted)
Density 1.036±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
pka 14.96±0.70(Predicted)
color White
LogP 7.590 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
NFPA 704
0
2 0

Protopanaxadiol Chemical Properties,Uses,Production

Description

(20)R-Protopanaxadiol is a sapogenin that has been found in P. ginseng and has anticancer and antibacterial activities. It has a cytotoxic concentration (CC50) value of 6.1 μM in MT-4 human T cell leukemia cells and inhibits the growth of several additional cancer cell lines, including A549 human lung carcinoma, SKOV3 human ovarian adenocarcinoma, SK-Mel-2 human melanoma, P388 and L1210 murine leukemia, and K562 human chronic leukemia cells (ED50s = 11-26 μM). (20)R-protopanaxadiol also inhibits the growth of H. pylori in vitro (MICs = 50-100 μg/ml).

Uses

20(R)-Protopanaxdiol is a saponin ginsenoside which is a signature phytochemical of Ginseng, an herbaceous plant. Anti-cancer agent.

Definition

ChEBI: A diastereomer of protopanaxadiol in which the 20-hydroxy substituent has been introduced at the pro-R position.

Protopanaxadiol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 104)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3424 58 Inquiry
Shaanxi Pioneer Biotech Co., Ltd . +8613259417953 China 3000 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26216 58 Inquiry
LEAP CHEM CO., LTD. +86-852-30606658 China 24738 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ZHEJIANG JIUZHOU CHEM CO., LTD +86-0576225566889 +86-13454675544 China 19947 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
(20R)-5α-Dammar-24-ene-3β,12β,20-triol (20R)-Dammar-24-ene-3β,12β,20-triol (20R)-Protopanaxadiol 20R-Protopanaxadiol PROTOVERATRINE A+B (RG)(CALL) Protopanaxadiol 20R-Betulafolienetriol Dammar-24-ene-3,12,20-triol, (3β,12β,20R)- Protopanaxadiol USP/EP/BP Protopanaxadiol, 98%, from Panax ginseng C. A. Mey. (3S,5R,8R,9R,10R,12R,13R,14R,17S)-17-((R)-2-Hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,12-diol 7755-01-3 775-01-3 Ginseng series Miscellaneous Natural Products