Salicylhydroxamic acid
- CAS No.
- 89-73-6
- Chemical Name:
- Salicylhydroxamic acid
- Synonyms
- SHAM;N,2-DIHYDROXYBENZAMIDE;sha;nsc5088;NSC 193440;AKOS BC-3099;Salicylhydroxamic;Salicylamide oxime;IFLAB-BB F1918-0014;alicylhydroxami acid
- CBNumber:
- CB5357798
- Molecular Formula:
- C7H7NO3
- Molecular Weight:
- 153.14
- MOL File:
- 89-73-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/24 17:36:38
| Melting point | 177 °C (dec.) (lit.) |
|---|---|
| Boiling point | 276.03°C (rough estimate) |
| Density | 1.3585 (rough estimate) |
| refractive index | 1.5500 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | Fine Crystalline Powder |
| pka | pK (25°) 4.19 |
| color | Beige-pink |
| Water Solubility | It is soluble in water. |
| Merck | 14,8331 |
| BRN | 1210520 |
| Stability | Stable. Incompatible with strong bases, strong oxidizing agents. Combustible. |
| CAS DataBase Reference | 89-73-6(CAS DataBase Reference) |
| EPA Substance Registry System | N,2-Dihydroxybenzamide (89-73-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H312+H332-H315-H319-H335-H351 | |||||||||
| Precautionary statements | P202-P280-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-40 | |||||||||
| Safety Statements | 22-26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VO6870000 | |||||||||
| HS Code | 29242990 | |||||||||
| NFPA 704 |
|
Salicylhydroxamic acid price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | S607 | Salicylhydroxamic acid 99% | 89-73-6 | 5G | ₹1634.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | S607 | Salicylhydroxamic acid 99% | 89-73-6 | 25G | ₹5607.35 | 2022-06-14 | Buy |
| TCI Chemicals (India) | S0008 | Salicylhydroxamic Acid | 89-73-6 | 5G | ₹1800 | 2022-05-26 | Buy |
| TCI Chemicals (India) | S0008 | Salicylhydroxamic Acid | 89-73-6 | 25G | ₹4600 | 2022-05-26 | Buy |
Salicylhydroxamic acid Chemical Properties,Uses,Production
Chemical Properties
It is a white needle crystal or off-white powder with a slow-heating melting point of 168°C. It is soluble in alcohol and ether and can be sublimated. When exposed to air, it progressively turns red. It is synthesized by combining methyl salicylate and hydroxylamine hydrochloride with sodium hydroxide, followed by acidification.
Uses
Salicylhydroxamic acid is a collector with efficient chelating effect on rare metal oxide minerals. It is used in rare metal beneficiation and has the advantages of good selectivity and strong collecting power. Salicylhydroxamic acid is mainly used as a complexing agent or extractant for rare earth ore, copper oxide ore, lead-zinc oxide ore, gold ore, kaolin, etc., as well as organic synthesis intermediates.
Definition
ChEBI: Salicylhydroxamic acid is a hydroxamic acid that is N-hydroxybenzamide carrying a phenolic hydroxy group at position 2. It has a role as an antibacterial drug, a trypanocidal drug, an EC 3.5.1.5 (urease) inhibitor and an EC 1.11.2.2 (myeloperoxidase) inhibitor. It is a member of phenols and a hydroxamic acid.
Preparation
The synthesis of salicylhydroxamic acid involved a two-step process. In the first step, methyl salicylate was prepared by esterifying salicylic acid with methanol using 28g (0.2 mol) of salicylic acid, 81 ml of methanol, and 8 ml of concentrated sulfuric acid. In the second step, hydroxylamine was coupled with the methyl salicylate. 13.9 g (0.2mol) of hydroxylamine was mixed with 200 ml of 10% sodium hydroxide solution and cooled. To this, 152.3g (0.1mol) of methyl salicylate was added in small portions with vigorous shaking after each addition to ensure complete dissolution. The mixture was allowed to stand for 36 hours, then acidified with 2M sulphuric acid and cooled. The precipitate was filtered, recrystallized from hot water containing a drop of acetic acid, recooled, and filtered. The yield of white precipitate collected and weighed was 14g of salicylhydroxamic acid.
Preparation and Characterization of Salicylhydroxamic acid and its Complexes with Iron (III), Cobalt (II) and Manganese (II)
Purification Methods
Crystallise the hydroxamic acid from acetic acid. [Beilstein 10 H 98.]
Salicylhydroxamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Syn Finechem Laboratories Pvt Ltd. | +91-9848230784 +91-9848230784 | Telangana, India | 423 | 58 | Inquiry |
| BASR Fine Chemicals Pvt. Ltd. | +91-9848230391 +91-9848230391 | Telangana, India | 908 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | China | 2503 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | China | 2989 | 55 | Inquiry |
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