ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Leucine derivatives >Fmoc-Leu-OH
Fmoc-Leu-OH
- CAS No.
- 35661-60-0
- Chemical Name:
- Fmoc-Leu-OH
- Synonyms
- FMOC-LEU-OH;FMOC-LEU;FMOC-L-LEU-OH;FMOC-LEUCINE;L-LEUCINE-N-FMOC;N-(fluorenyl-9-methoxycarbonyl)leucine;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid;F-L-LEU;NPC 15199;FMOC-L-LEU
- CBNumber:
- CB5477829
- Molecular Formula:
- C21H23NO4
- Molecular Weight:
- 353.41
- MOL File:
- 35661-60-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/12/11 16:06:43
| Melting point | 152-156 °C(lit.) |
|---|---|
| alpha | -26 º (c=1,DMF 24 ºC) |
| Boiling point | 486.83°C (rough estimate) |
| Density | 1.2107 (rough estimate) |
| refractive index | -25 ° (C=1, DMF) |
| storage temp. | Store below +30°C. |
| solubility | DMF (Slightly), DMSO (Slightly) |
| pka | 3.91±0.21(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]20/D 25±2°, c = 1% in DMF |
| BRN | 2178254 |
| Stability | Hygroscopic |
| InChIKey | CBPJQFCAFFNICX-IBGZPJMESA-N |
| CAS DataBase Reference | 35661-60-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36/37/39-27-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2924 29 70 | |||||||||
| NFPA 704 |
|
Fmoc-Leu-OH price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.52011 | Fmoc-Leu-OH Novabiochem? | 35661-60-0 | 25G | ₹2920 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52011 | Fmoc-Leu-OH Novabiochem? | 35661-60-0 | 100G | ₹4449.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52011 | Fmoc-Leu-OH Novabiochem? | 35661-60-0 | 250G | ₹10330 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52011 | Fmoc-Leu-OH Novabiochem? | 35661-60-0 | 8520110500 | ₹18590 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52011 | Fmoc-Leu-OH Novabiochem? | 35661-60-0 | 1KG | ₹31210.01 | 2022-06-14 | Buy |
Fmoc-Leu-OH Chemical Properties,Uses,Production
Description
Fmoc-Leu-OH is isomeric with Fmoc-Ile-OH. Like isoleucine, leucine has branching in the sidechain. The branching is at the gamma carbon instead of the beta carbon as in isoleucine. It is used in chemical and peptide syntheses.
Chemical Properties
white to light yellow crystal powde
Uses
Fmoc-L-Leu-OH, is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.
Application
Fmoc-Leu-OH can be used as a reactant to synthesize:
Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts.
A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus.
Streptocidin A?D, decapeptide antibiotics naturally found in Streptomyces?sp. Tü 6071.
Coumaroyl dipeptide amide that can be used for cosmetic applications.
Preparation
Fmoc-L-leucine is prepared by reacting L-leucine with 9-fluorenylmethoxycarbonyl chloride.
Biological Activity
Anti-inflammatory agent; increases intracellular Ca 2+ levels. PPARγ ligand that induces insulin sensitization, but not adipogenesis.
Fmoc-Leu-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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Global( 619)Suppliers
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|---|---|---|---|---|---|
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| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| TYNDAL LABS PVT LTD | 58 |
| TEADUS PHARMA PRIVATE LIMITED | 58 |
| SV CHEM INTERMEDITES PRIVATE LIMITED | 58 |
| JSK Chemicals | 58 |
| ALS INDIA LIFE SCIENCES | 58 |
| SIDDHI VINAYAKA SPECHEM PVT LTD | 58 |
| CJEX Biochem Pvt Ltd | 58 |
| Avra Synthesis Pvt Ltd | 30 |
| CHEMSWORTH | 30 |
35661-60-0(Fmoc-Leu-OH)Related Search:
L-Leucine
N-(9-Fluorenylmethoxycarbonyloxy)succinimide
N-CARBOBENZOXY-DL-LEUCINE
L-tert-Leucine
Glycine
Fmoc-Aib-OH
9-Fluorenylmethyl chloroformate
FMOC-Ala-OH
Fmoc-Lys(Boc)-OH
FMOC-N-METHYL-TRANEXAMIC ACID
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FMOC-L-LEU
FMOC-L-LEUCINE
F-L-LEU
Fmoc-L-leucine,98%
L-Leucine-1-13C-N-FMOC
Fmoc-N-(isobutyl)-glycine
FMOC-L-LEU-OH MONOHYDRATE
Fmoc-N-(isobutyl)-Gly-OH
FMOC-L-LEUCINE extrapure
N-(9-Fluorenylmethoxycarbonyl)-L-leucine, Fmoc-L-leucine
2-(9H-fFuoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-leucine ,98%
(2S)-4-Methyl-2-(9H-fluorene-9-ylmethoxycarbonylamino)valeric acid
(S)-2-[[(9H-Fluorene-9-yl)methoxycarbonyl]amino]-4-methylpentanoic acid
N-[(9H-Fluorene-9-yl)methoxycarbonyl]leucine
FMoc-L-leucine
FMoc-Leu-OH
2-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]AMINO]-4-METHYLPENTANOIC ACID
9-FLUORENYLMETHOXYCARBONYL-L-LEUCINE
Fmoc-Leucine-OH
FMoc-Nleu-OH
N-FMOC-LEU-OH
N-FMOC-L-LEU
N-FMOC-L-LEUCINE
NPC 15199
N-ALPHA-FMOC-L-LEUCINE
N-(9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE
N-9-FLUORENYLMETHYLOXYCARBONYL-L-LEUCINE
N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-LEUCINE
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-L-LEUCINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-LEUCINE
PPAR-GAMMA ACTIVATOR
N-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-L-leucine, (2S)-2-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanoic acid
N-Fmoc-L-leucine
Fmoc-Leu-OH
FMoc-Leu-OH >=97.0%
Fmoc-L-leucin
Fmoc-L-leucine≥ 99.7% (HPLC, Chiral purity)
(9H-Fluoren-9-yl)MethOxy]Carbonyl Leu-OH
(2R)-2-amino-3-[4-[4-[(2R)-2-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethyl]phenyl]phenyl]propanoic acid
FMOC-LEU-OH 250 G
FMOC-LEU-OH 100 G
L-Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoicaci
Fmoc-Leu-OH Fmoc-Leu-OH
FMOC-L-Leucine USP/EP/BP
Fmoc-L-leucine, puriss, 99%
FMOC-LEU-OH
FMOC-L-LEU-OH
N-(fluorenyl-9-methoxycarbonyl)leucine
FMOC-LEU
FMOC-LEUCINE
(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-4-Methylpentanoic acid
L-LEUCINE-N-FMOC
N-(9-Fluorenylmethoxycarbonyl)-L-leucine Fmoc-L-leucine 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid N-Fmoc-L-leucine
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine
35661-60-0
35661-60-6
C21H323NO4
CH32CHCH2CHNHFMOCCOOH