Fmoc-Gly-OH
- CAS No.
- 29022-11-5
- Chemical Name:
- Fmoc-Gly-OH
- Synonyms
- FMOC-GLY-OH;FMOC-GLY;FMOC-L-GLY;Fmoc-g;Fmoc-GL;FMOC-L-GLY-OH;FMOC-L-GLYCINE;FMoc-DL-Glycine;N-(fluoren-9-ylmethoxycarbonyl)glycine;npc14692
- CBNumber:
- CB4288480
- Molecular Formula:
- C17H15NO4
- Molecular Weight:
- 297.31
- MOL File:
- 29022-11-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/15 18:41:30
| Melting point | 174-175 °C(lit.) |
|---|---|
| Boiling point | 438.82°C (rough estimate) |
| Density | 1.1671 (rough estimate) |
| refractive index | 1.4500 (estimate) |
| storage temp. | 2-8°C |
| solubility | almost transparency in Methanol |
| pka | 3.89±0.10(Predicted) |
| form | Powder |
| color | White |
| BRN | 2163967 |
| InChI | InChI=1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20) |
| InChIKey | NDKDFTQNXLHCGO-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| CAS DataBase Reference | 29022-11-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29242995 | |||||||||
| NFPA 704 |
|
Fmoc-Gly-OH price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.52001 | Fmoc-Gly-OH Novabiochem? | 29022-11-5 | 25G | ₹2920 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52001 | Fmoc-Gly-OH Novabiochem? | 29022-11-5 | 100G | ₹4449.99 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.52001 | Fmoc-Gly-OH Novabiochem? | 29022-11-5 | 250G | ₹10330 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 47627 | Fmoc-Gly-OH ≥98.0% (T) | 29022-11-5 | 5G | ₹3193.38 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 47627 | Fmoc-Gly-OH ≥98.0% (T) | 29022-11-5 | 50G | ₹7003.78 | 2022-06-14 | Buy |
Fmoc-Gly-OH Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.
Preparation
Glycine (Gly) (0.5 g, 6.66 mmol) was dissolved in 10% NaCO3 (14 ml) under stirring in a 50-ml flask. To the resulting solution, which had been put into an ice bath, 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) (1.72 g, 6.66 mmol) in dioxane (12 ml) was gradually added. The reaction mixture was stirred at room temperature for 4 hours. Then added water (150 ml) to the mixture. The aqueous phase layer was separated from the reaction mixture and stripped with ether three times (75 ml×3). The stripped aqueous layer was acidified with 2N HCl aqueous solution to a pH=2, followed by extraction with ethyl acetate three times (75 ml×3). The organic phase layer was recovered and concentrated to obtain crude product of 1.70 g. The crude product was recrystallized in a mixed solvent of ethyl acetate hexane=1:2 (30 ml), and white solid denoted as Fmoc-Gly-OH was obtained after filtration at a reduced pressure.
General Description
The product number for this product was previously 04-12-1001.
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Fmoc-Gly-OH Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Advantage |
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| GLR Innovations | 58 |
| TEADUS PHARMA PRIVATE LIMITED | 58 |
| SV CHEM INTERMEDITES PRIVATE LIMITED | 58 |
| JSK Chemicals | 58 |
| ALS INDIA LIFE SCIENCES | 58 |
| SIDDHI VINAYAKA SPECHEM PVT LTD | 58 |
| CJEX Biochem Pvt Ltd | 58 |
| S.V. Chem Intermediates (P) Ltd. | 58 |
| Souvenier Chemicals | 58 |
| Globe Chemie | 50 |
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